PDK0411Compound PDK0411Compound PDK0411

价 格：￥电议型 号：PDK0411产 地：中国大陆

T8806FluzoparibSHR 3162,homologous recombination repair,Inhibitor,poly ADP ribose polymerase,Fluzoparib,i

fluzoparib is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.

价 格：￥电议型 号：T8806产 地：中国大陆

TQ0097AGN 193109AGN193109,Autophagy,Inhibitor,Retinoic acid receptors,Retinoid X receptors,RAR/RXR,AGN 193

AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).

价 格：￥电议型 号：TQ0097产 地：中国大陆

T8842IMT1BInhibitor,inhibit,POLRMT,oxidative,IMT-1B,LDC-203974,human,LDC 203974,anti-tumour,mtDNA,phospho

IMT1B is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression. It has anti-tumour effects.

价 格：￥电议型 号：T8842产 地：中国大陆

T7304DNQXinhibit,nucleus,selective,thalamic,Ionotropic glutamate receptors,Inhibitor,quinoxaline,DNQX,FG-

DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)

价 格：￥电议型 号：T7304产 地：中国大陆

T6866AUZ 454AUZ454,ACHN,Caki-1,cells,K 03861,K-03861,Cyclin dependent kinase,AUZ-454,AUZ 454,Inhibitor,in

K03861 is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.

价 格：￥电议型 号：T6866产 地：中国大陆

T60205(2S)-4-biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide(2S)4biphenyl4ylNhydroxy2methyl2

(2S)-4-biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide is a LpxC inhibitor with IC50 >95.2 nM.

价 格：￥电议型 号：T60205产 地：中国大陆

T6793BRD7552promoter,BRD-7552,islets,human,inhibit,epigenetic,ductal,changes,insulin,BRD 7552,BRD7552,pri

BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells.

价 格：￥电议型 号：T6793产 地：中国大陆

T7695PNU-282987 S enantiomer free baseInhibitor,Nicotinic acetylcholine receptors,PNU 282987 S enantiomer

PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR).

价 格：￥电议型 号：T7695产 地：中国大陆

TN1140Onjisaponin BAutophagy,Onjisaponin B,Inhibitor,inhibit

Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parkinson disease, Alzheimer disease and Huntington disease.

价 格：￥电议型 号：TN1140产 地：中国大陆

T7827Glycyrrhizinic acid, potassium saltGlycyrrhizinic acid, potassium salt

Glycyrrhizinic acid, potassium salt can reduce ventricular arrhythmias caused by veratrol

价 格：￥电议型 号：T7827产 地：中国大陆

T79912-Hydroxycinnamic acidSARS coronavirus,Human immunodeficiency virus,inhibit,2Hydroxycinnamic acid,In

2-Hydroxycinnamic acid is a natural product isolated from Angraecum fragrans, has photooxidant activity.

价 格：￥电议型 号：T7991产 地：中国大陆

T7336ICA-121431Nav,Na channels,inhibitor,ICA-121431,ICA 121431,TTX-resistant,Sodium Channel,channel,Na+ c

ICA-121431 is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, with little or no activity against human Nav1.5 or Nav1.7 channels.

价 格：￥电议型 号：T7336产 地：中国大陆

T7200TAK-960Polo-like Kinase (PLK),cell,cancer,proliferation,Inhibitor,mitosis,TAK960,TAK 960,leukemia,in

TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.

价 格：￥电议型 号：T7200产 地：中国大陆

TN2330Phenethyl ferulatePhenethyl ferulate,Lipoxygenase,5-LOX,Cyclooxygenase,Inhibitor,5-lipoxygenase,inhi

Caffeic Acid 3-Methyl Phenethyl Ester has chemopreventive properties against chemically induced colon carcinogenesis. It enhances apoptosis in azoxymethane induced colon tumors. It shows inhibitory activity against cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) with IC50 values of 4.35 μM and 5.75 μM, respectively.

价 格：￥电议型 号：TN2330产 地：中国大陆

TN2264Terpinen-4-olInhibitor,oil,Endogenous Metabolite,Terpinen 4 ol,Terpinen4ol,tea-tree,chemotherapeutic

Terpinine-4-ol is a natural product from Pimpinella yunnanensis.

价 格：￥电议型 号：TN2264产 地：中国大陆

TQ0155Miglustat hydrochlorideN-Butyldeoxynojirimycin,OGT-918,type I gaucher disease,Miglustat,Miglustat hy

Miglustat hydrochloride is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher disease.

价 格：￥电议型 号：TQ0155产 地：中国大陆

T9000PyrimorphPhytophthora capsici,Fungal,Cell wall,Cystospore germination,Pyrimorph,inhibit,Inhibitor,My

Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici. Pyrimorph inhibited different stages in the life cycle of P. capsici including mycelial growth, sporangium production, zoospore release, and cystospore germination with EC(50) values of 1.84, 0.17, 4.92, and 0.09 microg mL(-1), respectively.

价 格：￥电议型 号：T9000产 地：中国大陆

Fr13634Compound Fr13634Compound Fr13634

价 格：￥电议型 号：Fr13634产 地：中国大陆

T8799(E/Z)-IT-603GVHD,Inhibitor,Nuclear factor-kappaB,(E/Z)IT603,immunomodulatory,(E/Z) IT 603,disease,in

IT-603 is a cell-permeable c-Rel inhibitor (IC50: 3μM). IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding and transcriptional activity.

价 格：￥电议型 号：T8799产 地：中国大陆