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T11438GNE-1858;化合物GNE-1858GNE-1858
GNE-1858 is an ATP-competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor (IC50s of 1.9 nM, 1.9 nM, and 4.5 nM for wild-type and the active mimetic mutants HPK1-TSEE and HPK1-SA).
价 格:¥电议型 号:T11438产 地:中国大陆
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T11437GNE-0439;化合物 T11437GNE-0439
GNE-0439 is a novel Nav1.7-selective inhibitor (IC50: 0.34 uM) and inhibits Nav1.5 (IC50: 38.3 μM). GNE-0439 inhibits mutant N1742K channels (IC50: 0.37 uM) in membrane potential assays.
价 格:¥电议型 号:T11437产 地:中国大陆
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T11431Glycosidase-IN-2;化合物 T11431Glycosidase-IN-2
Glycosidase-IN-2 is a glycosidase inhibitor with hypoglycemic activity.
价 格:¥电议型 号:T11431产 地:中国大陆
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T11430Glycosidase-IN-1;化合物 T11430Glycosidase-IN-1
Glycosidase-IN-1 is a glycosidase inhibitor synthesized from D-mannose with hypoglycemic activity. It can be used to synthesize some immunosuppressive agents and β-glucosidase inhibitors.
价 格:¥电议型 号:T11430产 地:中国大陆
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T11421Glutaminase-IN-1;谷氨酰胺酶抑制剂1CB839 derivative;CB839 derivative
Glutaminase-IN-1 (CB839 derivative), a novel 1,3,4-selenodiazepine renal-type glutaminase (KGA) variant inhibitor, showed antitumor activity in an aggressive H22 hepatocellular carcinoma xenograft model.
价 格:¥电议型 号:T11421产 地:中国大陆
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T11419O6BTG-octylglucoside化合物 T11419Glucose-conjugated MGMT inhibitor
O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).
价 格:¥电议型 号:T11419产 地:中国大陆
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T11337Fumarate hydratase-IN-1;Fumarate hydratase 抑制剂1Fumarate hydratase-IN-1
Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor with antiproliferative activity and can be used to study cellular activity.
价 格:¥电议型 号:T11337产 地:中国大陆
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T11336Fumarate hydratase-IN-2 sodium salt化合物 T11336Fumarate hydrataseIN2 sodium salt|||Fumarate hydratase
Fumarate hydratase-IN-2 sodium salt (compound 3) is a cell-permeable and competitive fumarate hydratase inhibitor ( K i =4.5 μM). Fumarate hydratase-IN-2 sodium salt has nutrient-dependent cytotoxicity [1].
价 格:¥电议型 号:T11336产 地:中国大陆
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T11333Fulvene-5;化合物 T11333Fulvene-5
Fulvene-5 is a chemical compound that exhibits antitumor activity. It functions as a potent inhibitor of NADPH oxidase 4 (NOX4) and possesses antioxidant properties. Additionally, Fulvene-5 acts as a reactive oxygen species (ROS) modifying agent and a powerful radioprotector.
价 格:¥电议型 号:T11333产 地:中国大陆
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T11276Fexofenadine-d6;非索非那定 d6MDL-16455-d6|||Terfenadine carboxylate-d6;MDL-16455-d6|||Terfenadine carboxy
Fexofenadine-d6 (MDL-16455-d6) is the deuterium substituent of Fexofenadine and can be used as an internal standard for the determination of non-sofenadine concentrations in human plasma.
价 格:¥电议型 号:T11276产 地:中国大陆
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T11252Ezetimibe phenoxy glucuronide-D4;化合物 T11252Ezetimibe β-D-glucuronide-D4|||Ezetimibe glucuronide-D4;E
Ezetimibe phenoxy glucuronide-D4 (Ezetimibe glucuronide-D4) is the deuterium labeled Ezetimibe phenoxy glucuronide.
价 格:¥电议型 号:T11252产 地:中国大陆
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T11250Ezetimibe-d4;化合物 T11250SCH 58235 D4;SCH 58235 D4
Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activation of Nrf2.
价 格:¥电议型 号:T11250产 地:中国大陆
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T11200Endoxifen (E-isomer);N-去甲-4-羟基-三苯氧胺E-Endoxifen|||Endoxifen E-isomer;N-去甲-4-羟基-三苯氧胺|||E-Endoxifen|||E
Endoxifen E-isomer (E-Endoxifen) is the E-isomer of (Z)-Endoxifen. Endoxifen E-isomer has antiestrogenic effects.
价 格:¥电议型 号:T11200产 地:中国大陆
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T11152Edaravone-d5;化合物 T11152MCI-186 D5;MCI-186 D5
Edaravone, a novel and potent free radical scavenger, effectively prevents MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Its deuterium-labeled variant, Edaravone D5, retains the original compound´s attributes while offering isotopic labeling benefits.
价 格:¥电议型 号:T11152产 地:中国大陆
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T11136E-7386;化合物E-7386E7386;E7386
E-7386 is an oral active CBP/ -catenin modulator.
价 格:¥电议型 号:T11136产 地:中国大陆
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T11092DPBQ;化合物DPBQZINC1620467|||2,3-Diphenylbenzo[g]quinoxaline-5,10-dione;ZINC1620467|||2,3-Diphenylbenzo
DPBQ (ZINC1620467) is a p53 activator. DPBQ could activate p53 and trigger apoptosis in a polyploid-specific manner, without inhibition of topoisomerase or bind DNA.
价 格:¥电议型 号:T11092产 地:中国大陆
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T11074Dolutegravir intermediate-1;化合物Dolutegravir intermediate-11-(2,2-dimethoxyethyl)-5-methoxy-6-methoxy
Dolutegravir intermediate-1 (1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid) is a new synthetic Dolutegravir intermediate. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-1 infection.
价 格:¥电议型 号:T11074产 地:中国大陆
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T11049Diprotin A TFA化合物 T11049Ile-Pro-Pro (TFA)
Diprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV).
价 格:¥电议型 号:T11049产 地:中国大陆
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T10953Dafadine-A;化合物Dafadine-ADafadine-A
Dafadine-A is an analog of dafadine and a novel inhibitor of DAF-9 cytochrome P450 in the nematode Caenorhabditis elegans. Mammalian orthologs that also inhibit DAF-9 (CYP27A1).
价 格:¥电议型 号:T10953产 地:中国大陆
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T10948MMAE-d8;化合物 T10948D8-MMAE|||D8-Monomethyl auristatin E;D8-MMAE|||D8-Monomethyl auristatin E
D8-MMAE (D8-Monomethyl auristatin E) is an effective mitotic inhibitor and tubulin inhibitor, deuterated MMAE.
价 格:¥电议型 号:T10948产 地:中国大陆