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T10436AZD4573;化合物AZD4573AZD4573
AZD4573 is an effective and selective CDK9 inhibitor (IC50: <4 nM). It enables transient target engagement for the treatment of hematologic malignancies.
价 格:¥电议型 号:T10436产 地:中国大陆
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T10435Linaprazan;利那拉生AZD0865;利那拉生|||AZD0865
Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.
价 格:¥电议型 号:T10435产 地:中国大陆
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T10434AZD-5991;化合物 T10434AZD-5991
AZD-5991 is a potent and selective Mcl-1 inhibitor (IC50: 0.7 nM in FRET assay; Kd: 0.17 nM in SPR assay).
价 格:¥电议型 号:T10434产 地:中国大陆
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T10433Osimertinib dimesylate奥希替尼二甲磺酸盐奥希替尼二甲磺酸盐|||Mereletinib (dimesylate)|||AZD-9291 (dimesylate)
Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).
价 格:¥电议型 号:T10433产 地:中国大陆
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T10432LAZD-8529 mesylate;化合物AZD-8529 mesylateAZD-8529 mesylate
AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.
价 格:¥电议型 号:T10432L产 地:中国大陆
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T10432AZD-8529;化合物 T10432AZD-8529
AZD-8529 is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.
价 格:¥电议型 号:T10432产 地:中国大陆
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T10431Golidocitinib;化合物AZD4205AZD4205;AZD4205
Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).
价 格:¥电议型 号:T10431产 地:中国大陆
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T10430AZD 2066;化合物 T10430AZD 2066
AZD 2066 is a selective, orally active, and brain-penetrant mGluR5 antagonist with analgesic activity.
价 格:¥电议型 号:T10430产 地:中国大陆
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T1043Multifungin;溴柳氯苯胺Bromochlorosalicylanilide|||Salifungin;Bromochlorosalicylanilide|||溴柳氯苯胺|||Salifung
Multifungin (Bromochlorosalicylanilide) is an antifungal that studies oral candidiasis. It reduces the number of fungal populations in corn during storage and prevents the formation and accumulation of zearalenone.
价 格:¥电议型 号:T1043产 地:中国大陆
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T10377Artefenomel;化合物 T10377OZ439;OZ439
Artefenomel (OZ439) is a synthetic antimalarial agent with the artemisinin pharmacophore.
价 格:¥电议型 号:T10377产 地:中国大陆
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T10343AOH1160;化合物AOH1160N-(2-Oxo-2-(2-phenoxyphenylamino)ethyl)-1-naphthamide;N-(2-Oxo-2-(2-phenoxyphenyla
AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA). AOH1160 induces apoptosis and causes cell-cycle arrest by interfering with DNA replication.
价 格:¥电议型 号:T10343产 地:中国大陆
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T10319LAnamorelin Fumarate;富马酸阿拉莫林ONO-7643 Fumarate|||RC1291 Fumarate;ONO-7643 Fumarate|||RC1291 Fumarate||
Anamorelin Fumarate is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay).
价 格:¥电议型 号:T10319L产 地:中国大陆
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T10243Ibezapolstat;化合物 T10243ACX-362E;ACX-362E
ACX-362E is an orally available DNA polymerase IIIC (pol IIIC) inhibitor, acts as an antimicrobial agent to treat Gram-positive infections (MIC50: 2 μg/mL for C. difficile).
价 格:¥电议型 号:T10243产 地:中国大陆
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T10213A-437203;化合物A-437203ABT-925|||A37203|||Lu201640;ABT-925|||A37203|||Lu201640
A-437203 (Lu201640) is A kind of based on 1 h - pyrimidin - 2 - one sca ? old, selective, new powerful d3 receptor antagonist, on D2, d3, and D4 receptor, Ki value 71, respectively 1.6 and 6220 nM.
价 格:¥电议型 号:T10213产 地:中国大陆
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T10207A 438079;化合物A 438079A 438079
A 438079 is a potent, and selective antagonist of P2X7 receptor (pIC50: 6.9).
价 格:¥电议型 号:T10207产 地:中国大陆
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T1004311-Oxomogroside IIe;11-氧罗汉果苷11-Oxomogroside IIe
11-Oxomogroside IIe is a triterpene glycoside isolated from Siraitia grosvenori[1].
价 格:¥电议型 号:T10043产 地:中国大陆
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T0991Desipramine hydrochloride盐酸去甲咪嗪NSC-114901|||Desmethylimipramine|||盐酸去甲咪嗪|||JB-8181|||EX-4355|||Norim
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-uptake of neurotransmitters, including norepinephrine and serotonin. This leads to an increase in the amount of these neurotransmitters in the synaptic cleft and prolongs their activities postsynaptically.
价 格:¥电议型 号:T0991产 地:中国大陆
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T0947LDexamethasone Phosphate disodium;地塞米松磷酸二钠EGP-437|||EGP437. Dex-Phos|||EGP 437;地塞米松磷酸二钠|||EGP-437|||E
Dexamethasone Phosphate disodium (EGP437. Dex-Phos) is a water-soluble form of the synthetic glucocorticoid dexamethasone.
价 格:¥电议型 号:T0947L产 地:中国大陆
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T0943Carbamazepine;卡马西平NSC 169864;卡马西平|||NSC 169864
Carbamazepine (NSC-169864) is a tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysynaptic responses and blocking post-tetanic potentiation. Its analgesic activity is not understood; however, carbamazepine is commonly used to treat pain associated with trigeminal neuralgia.
价 格:¥电议型 号:T0943产 地:中国大陆
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T0768LOxolamine hydrochloride;化合物 T0768LOxolamine HCl|||683 M hydrochloride|||AF 438 hydrochloride;Oxolami
Oxolamine hydrochloride is a cough suppressant which may be useful in the treatment of pediatric asthma.
价 格:¥电议型 号:T0768L产 地:中国大陆