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T18339Methyltetrazine-PEG13-acid；化合物 T18339Methyltetrazine-PEG13-acid
Methyltetrazine-PEG13-acid is a PEGylated linker derived from PEG that serves as a valuable component in the production of PROTACs, a class of compounds known for their targeted protein degradation properties[1].
价 格：￥电议型 号：T18339产 地：中国大陆
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T18338Methyltetrazine-amido-PEG7-azide；化合物 T18338Methyltetrazine-amido-PEG7-azide
Methyltetrazine-amido-PEG7-azide is a PEG-based PROTAC linker, employed for the synthesis of PROTACs[1].
价 格：￥电议型 号：T18338产 地：中国大陆
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T18337Methyltetrazine-amido-PEG5-alkyne；化合物 T18337Methyltetrazine-amido-PEG5-alkyne
Methyltetrazine-amido-PEG5-alkyne is a polyethylene glycol (PEG) derivative commonly employed as a linker for proteolysis targeting chimeras (PROTACs) synthesis [1].
价 格：￥电议型 号：T18337产 地：中国大陆
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T18336Methylcyclopropene-PEG4-NHS；化合物 T18336Methylcyclopropene-PEG4-NHS
Methylcyclopropene-PEG4-NHS is a four-unit PEG ADC linker, which can be cleaved. It is utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T18336产 地：中国大陆
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T18335Methylcyclopropene-PEG3-amine；化合物 T18335Methylcyclopropene-PEG3-amine
Methylcyclopropene-PEG3-amine is a cleavable three-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T18335产 地：中国大陆
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T18334Methoxy-Tr-NH-PEG7；化合物 T18334Methoxy-Tr-NH-PEG7
Methoxy-Tr-NH-PEG7 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18334产 地：中国大陆
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T18333mDPR(Boc)-Val-Cit-PAB；化合物 T18333mDPR(Boc)-Val-Cit-PAB
mDPR(Boc)-Val-Cit-PAB is a cleavable linker employed in antibody-drug conjugates (ADCs) [1]. This chemical compound serves as a reliable linker in the formation of ADCs, which are biopharmaceuticals that combine the specificity of monoclonal antibodies with the potency of cytotoxic drugs for targeted cancer therapy [1].
价 格：￥电议型 号：T18333产 地：中国大陆
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T18332MC-VC-PABC-Aur0101；化合物 T18332MCVCPABCAur0101|||MC-VC-PABC-Aur-0101|||MC VC PABC Aur0101|||MC-VC-PABC
MC-VC-PABC-Aur0101 is a potent anticancer drug-linker conjugate designed for Antibody-Drug Conjugates (ADCs), comprising Aur0101, an auristatin microtubule inhibitor, connected through the MC-VC-PABC linker to enhance antitumor efficacy.
价 格：￥电议型 号：T18332产 地：中国大陆
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T18331MC-VC-PABC-DNA31；化合物 T18331MC-VC-PABC-DNA31
MC-VC-PABC-DNA31 is a drug-linker conjugate designed for Antibody-Drug Conjugates (ADC) that demonstrates potent antitumor activity. It employs DNA31, an effective inhibitor of RNA polymerase, connected through the MC-VC-PABC ADC linker.
价 格：￥电议型 号：T18331产 地：中国大陆
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T18330MC-Val-Cit-PAB-vinblastine；化合物 T18330MC-Val-Cit-PAB-vinblastine
MC-Val-Cit-PAB-vinblastine is a potent antitumor drug-linker conjugate for Antibody-Drug Conjugates (ADC), featuring vinblastine (a microtubule protein inhibitor) connected through the MC-Val-Cit-PAB ADC linker.
价 格：￥电议型 号：T18330产 地：中国大陆
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T1833NSI189化合物NSI-189NSI-189|||NSI 189
NSI189 (NSI-189) is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.
价 格：￥电议型 号：T1833产 地：中国大陆
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T18329MC-VC(S)-PABQ-Tubulysin M；化合物 T18329MC-Val-Cit-PAB-tubulysin5a；MC-Val-Cit-PAB-tubulysin5a
MC-Val-Cit-PAB-tubulysin5a is a drug-linker conjugate for ADC with potent antitumor activity by using tubulysin5a (a tubulin inhibitor), linked via the ADC linker MC-Val-Cit-PAB.
价 格：￥电议型 号：T18329产 地：中国大陆
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T18328MC-Val-Cit-PAB-rifabutin；化合物 T18328MC-Val-Cit-PAB-rifabutin
MC-Val-Cit-PAB-rifabutin is a drug-linker conjugate designed for antibody-drug conjugates (ADC), featuring the potent antitumor agent rifabutin (a DNA-dependent RNA polymerase inhibitor) connected through the MC-Val-Cit-PAB ADC linker. This configuration endows it with significant antitumor activity.
价 格：￥电议型 号：T18328产 地：中国大陆
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T18327MC-Val-Cit-PAB-Retapamulin；化合物 T18327MC-Val-Cit-PAB-Retapamulin
MC-Val-Cit-PAB-Retapamulin is a drug-linker conjugate for antibody-drug conjugates (ADC) that exhibits potent antitumor activity. This compound utilizes Retapamulin, a ribosome inhibitor, connected through the ADC linker MC-Val-Cit-PAB.
价 格：￥电议型 号：T18327产 地：中国大陆
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T18326MC-Val-Cit-PAB-MMAF；化合物 T18326MC-Val-Cit-PAB-MMAF
MC-Val-Cit-PAB-MMAF is an antibody-drug conjugate (ADC) component that exhibits antitumor properties through the action of the tubulin inhibitor, monomethyl auristatin F (MMAF), which is connected by a cathepsin-cleavable linker, MC-Val-Cit-PAB.
价 格：￥电议型 号：T18326产 地：中国大陆
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T18324MC-Val-Cit-PAB-duocarmycin chloride；化合物 T18324MC-Val-Cit-PAB-duocarmycin；MC-Val-Cit-PAB-duocarmycin
MC-Val-Cit-PAB-duocarmycin is an antibody-drug conjugate (ADC) linker that combines duocarmycin, a potent DNA minor groove-binding alkylating agent, with an antitumor drug through the MC-Val-Cit-PAB linker, exhibiting significant antitumor activity.
价 格：￥电议型 号：T18324产 地：中国大陆
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T18323MC-Val-Cit-PAB-dimethylDNA31；化合物 T18323MC-Val-Cit-PAB-dimethylDNA31
MC-Val-Cit-PAB-dimethylDNA31 is a drug-linker conjugate employed in antibody-drug conjugates (ADCs) that exhibits robust antitumor efficacy. This conjugate utilizes the ADC linker, MC-Val-Cit-PAB, to link to the potent antitumor agent dimethylDNA31. Notably, dimethylDNA31 also demonstrates significant bactericidal activity against both persister and stationary-phase Staphylococcus aureus.
价 格：￥电议型 号：T18323产 地：中国大陆
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T18322MC-Val-Cit-PAB-clindamycin；化合物 T18322MC-Val-Cit-PAB-clindamycin
MC-Val-Cit-PAB-clindamycin is an antibody-drug conjugate (ADC) linker that combines the potent antitumor properties of clindamycin, a protein synthesis inhibitor, with the ADC linker MC-Val-Cit-PAB, to enhance its ability to target and kill cancer cells effectively.
价 格：￥电议型 号：T18322产 地：中国大陆
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T18321Mc-Val-Cit-PAB-Cl；化合物Mc-Val-Cit-PAB-ClMc-Val-Cit-PAB-Cl
Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC50s of 3.3 and 0.95 nM against BJAB and WSU cell lines, respectively.
价 格：￥电议型 号：T18321产 地：中国大陆
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T18320MC-Val-Cit-PAB-carfilzomib iodide；化合物 T18320MC-Val-Cit-PAB-carfilzomib；MC-Val-Cit-PAB-carfilzomib
MC-Val-Cit-PAB-carfilzomib is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADC), comprising the irreversible proteasome inhibitor carfilzomib, connected through the ADC linker MC-Val-Cit-PAB.
价 格：￥电议型 号：T18320产 地：中国大陆
