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  • T11908LY2365109 hydrochlorideLY2365109盐酸盐LY2365109盐酸盐

    LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.

    价 格：￥电议型 号：T11908产 地：中国大陆

  • T11851Lin28-let-7a antagonist 1；化合物Lin28-let-7a antagonist 1Lin28-let-7a antagonist 1

    Lin28-let-7a antagonist 1, with an IC50 of 4.03 μM for Lin28A-let-7a-1 interaction，and shows a clear antagonistic effect against the Lin28-let-7a interaction.

    价 格：￥电议型 号：T11851产 地：中国大陆

  • T11847LLiarozole；利阿唑R75251 dihydrochloride；R75251 dihydrochloride|||利阿唑

    Liarozole (R75251 dihydrochloride) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase).Liarozole dihydrochloride is an imidazole derivative; it is being investigated as a non-hormonal agent in prostate cancer and in the treatment of various other cancers and skin disorders.

    价 格：￥电议型 号：T11847L产 地：中国大陆

  • T11847Liarozole dihydrochloride；化合物 T11847R75251 dihydrochloride；R75251 dihydrochloride

    Liarozole dihydrochloride is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase).Liarozole dihydrochloride is an imidazole derivative; it is being investigated as a non-hormonal agent in prostate cancer and in the treatment of various other cancers and skin disorders.

    价 格：￥电议型 号：T11847产 地：中国大陆

  • T11798L-692429；化合物L-692429MK-0751；MK-0751

    L-692429 (MK-0751) is a potent nonpeptidyl growth hormone secretagogue (GHS) agonist, a benzolactam derivative, which reverses the inhibition of GH secretion by glucocorticoids.L-692429 has a high affinity for the G protein-coupled receptor and can be used in the study of acromegaly and obesity. L-692429 has a high affinity for G protein-coupled receptor and can be used to study acromegaly and obesity.

    价 格：￥电议型 号：T11798产 地：中国大陆

  • T11751KDOAM-25；化合物 T11751KDOAM-25

    KDOAM-25, a potent and highly selective inhibitor of histone lysine demethylases 5 (KDM5) with IC50 values of 71 nM for KDM5A, 19 nM for KDM5B, 69 nM for KDM5C, and 69 nM for KDM5D, enhances global H3K4 methylation at transcriptional start sites and reduces proliferation in multiple myeloma MM1S cells.

    价 格：￥电议型 号：T11751产 地：中国大陆

  • T11732JTV-519 hemifumarate；化合物 T11732K201 hemifumarate；K201 hemifumarate

    JTV-519 hemifumarate,Antiarrhythmic and cardioprotective properties. is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle.

    价 格：￥电议型 号：T11732产 地：中国大陆

  • T11731LJTV-519 Formate；化合物JTV-519 FormateJTV-519 Formate (145903-06-6 Free base)；JTV-519 Formate (145903-06

    JTV-519 Formate is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA). JTV-519 Formate is also a partial agonist of ryanodine receptors in striated muscle. JTV-519 Formate exhibits antiarrhythmic and cardioprotective properties.

    价 格：￥电议型 号：T11731L产 地：中国大陆

  • T11731JTV-519 free base；化合物 T11731K201 free base；K201 free base

    JTV-519 free base (K201 free base), recognized for its antiarrhythmic and cardioprotective properties, functions as a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and serves as a partial agonist of ryanodine receptors in striated muscle.

    价 格：￥电议型 号：T11731产 地：中国大陆

  • T11730JTT 551；化合物 T11730JTT551|||JTT 551|||JTT-551|||JTT 551；JTT551|||JTT 551|||JTT-551|||JTT 551

    JTT 551 can be used in the research of type 2 diabetes mellitus. JTT 551 is selective a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with Kis of 0.22 μM and 9.3 μM for PTP1B and TCPTP (T-cell protein tyrosine phosphatase), respectively.

    价 格：￥电议型 号：T11730产 地：中国大陆

  • T11718JI051；化合物JI051JI-051；JI-051

    JI051 is an antitumor agent that interacts with the cancer-associated protein chaperone prohibitin 2 (PHB2) to induce cell cycle arrest by inhibiting the transcription of the Notch downstream effector gene, Hes1, and inhibits the proliferation of HEK293 cells and pancreatic cancer cells.

    价 格：￥电议型 号：T11718产 地：中国大陆

  • T11651Indanidine；吲达尼定Indanidine

    Indanidine is a highly selective and potent α-adrenergic agonist with antihypertensive activity.Indanidine is an α-adrenergic antagonist that can be used in the study of neurological disorders.

    价 格：￥电议型 号：T11651产 地：中国大陆

  • T11607ICI 118,551 hydrochloride；化合物ICI 118,551 hydrochlorideICI 118551 hydrochloride；ICI 118551 hydrochlor

    ICI 118,551 hydrochloride (ICI 118551 hydrochloride) is a highly selective β2 adrenergic receptor antagonist (Kis: 0.7, 49.5, and 611 nM for β2, β1, and β3 receptors).

    价 格：￥电议型 号：T11607产 地：中国大陆

  • T11606ICA-105665；化合物 T11606PF-04895162；PF-04895162

    ICA-105665 (PF-04895162) is a potent and orally active neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels opener. ICA-105665 had low cytotoxic potential in human hepatocytes but inhibited liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the central nervous system (CNS) and has antiseizure effects[1][2][3][4].

    价 格：￥电议型 号：T11606产 地：中国大陆

  • T11551Helvolic acid；化合物 T11551Fumigacin；Fumigacin

    Helvolic acid, an antibiotic derived from Xylaria sp., exhibits effectiveness against Gram-positive bacteria.

    价 格：￥电议型 号：T11551产 地：中国大陆

  • T11519GW768505A free base；化合物 T11519GW768505A free base

    GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2 (pIC50: 7.81 for VEGFR2) with anti-angiogenic activity.

    价 格：￥电议型 号：T11519产 地：中国大陆

  • T11518LGW274150；化合物GW274150GW274150

    GW274150 is an orally active, selective and potent dual inhibitor of NADPH-dependent human nitric oxide synthase (iNOS) (Kd=40 nM) and rat inducible nitric oxide synthase (iNOS).GW274150 has a low activity against endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) in humans and rats. GW274150 showed protective effects in an inflammatory model of acute lung injury.

    价 格：￥电议型 号：T11518L产 地：中国大陆

  • T11518GW274150 phosphate；化合物 T11518GW274150 phosphate

    GW274150 phosphate is a selective, orally active, and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50: 2.19 μM; Kd: 40 nM) and rat iNOS (ED50: 1.15 μM).

    价 格：￥电议型 号：T11518产 地：中国大陆

  • T11517GV-58；化合物GV-58GV-58

    GV-58 is a selective N- and P/Q-type Ca2+ channels agonist (EC50: 7.21/8.81 uM for N-type/P-Q-type Ca2+ channel). The inhibitory of GV-58 is 20-fold fewer for CDK kinases activity.

    价 格：￥电议型 号：T11517产 地：中国大陆

  • T11516GV-196771A；化合物GV-196771AGV-196771A

    GV-196771A A novel NMDA receptor glycine site antagonist with potent antinociceptive activity.

    价 格：￥电议型 号：T11516产 地：中国大陆

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