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T11477GSK1059865;化合物 T11477GSK1059865
GSK1059865 is a potent antagonist of the orexin 1 receptor.
价 格:¥电议型 号:T11477产 地:中国大陆
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T11447GNF4877;化合物GNF4877GNF4877
GNF4877 is a potent DYRK1A and GSK3β inhibitor (IC50s: 6 nM and 16 nM). It leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation cells.
价 格:¥电议型 号:T11447产 地:中国大陆
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T11377GDC-0276;化合物 T11377GDC-0276
GDC-0276, a potent, selective, reversible, and orally active NaV1.7 inhibitor with an IC50 value of 0.4 nM, offers potential for pain treatment while overcoming limitations associated with current pain medications, including addiction and off-target side effects. It is well tolerated and demonstrates a favorable pharmacokinetic profile.
价 格:¥电议型 号:T11377产 地:中国大陆
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T11313Forodesine hydrochloride化合物 T11313BCX-1777 hydrochloride|||Immucillin-H hydrochloride
Forodesine hydrochloride (BCX-1777 hydrochloride), a potent inhibitor of human lymphocyte proliferation, effectively induces apoptosis in leukemic cells by elevating dGTP levels. This compound is an orally active, highly potent purine nucleoside phosphorylase (PNP) inhibitor, demonstrating IC50 values between 0.48 to 1.57 nM across human, mouse, rat, monkey, and dog PNP.
价 格:¥电议型 号:T11313产 地:中国大陆
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T11277FG 7142;化合物FG 7142ZK 39106|||LSU-65;ZK 39106|||LSU-65
FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM).
价 格:¥电议型 号:T11277产 地:中国大陆
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T1124Flumethasone氟米松氟米松|||Flumetasone|||RS-2177|||NSC-54702
Flumethasone (RS-2177) is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
价 格:¥电议型 号:T1124产 地:中国大陆
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T11229Erlotinib-d6;化合物 T11229OSI-774 D6|||NSC 718781 D6|||CP-358774 D6;OSI-774 D6|||NSC 718781 D6|||CP-358
Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .
价 格:¥电议型 号:T11229产 地:中国大陆
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T11220LUK 227786;化合物T11220Lhydrochloride(150452-18-9 Free base)|||1-[4-(1,3-Benzodioxol-5a-ylmethylamino)-6
UK 227786 is an inhibitor of phosphodiesterase 5 (PDE5), used for treatment of prostatic diseases.
价 格:¥电议型 号:T11220L产 地:中国大陆
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T11177Elinogrel;化合物ElinogrelPRT060128;PRT060128
Elinogrel (PRT060128) is a competitive and reversible antagonist of platelet P2Y12 with IC50 of 20 nM and exhibits potent antiplatelet effects.
价 格:¥电议型 号:T11177产 地:中国大陆
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T11154LEG01377 2HCl;EG01377二盐酸盐EG01377 2HCl(2227996-00-9 Free base);EG01377 2HCl(2227996-00-9 Free base)
EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377 2HCl against NRP1-a1 and NRP1-b1.EG01377 exhibits anti-angiogenic, antimigratory and antitumor activities.
价 格:¥电议型 号:T11154L产 地:中国大陆
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T11154EG01377;化合物 T11154EG01377
EG01377 has antiangiogenic, antimigratory, and antitumor effects.EG01377 is a neuropilin-1 (NRP1) antagonist, with a Kd of 1.32 μM for NRP1-b1, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1, but shows no effect on NRP2.
价 格:¥电议型 号:T11154产 地:中国大陆
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T11150Ecteinascidin 770;化合物 T11150Ecteinascidine 770|||Et-770;Ecteinascidine 770|||Et-770
Ecteinascidin 770 (ET-770) inhibits U373MG cells and is a 1,2,3, 4-tetrahydroisoquinoline alkaloid with strong anticancer activity.IC50 is 4.83 nM.
价 格:¥电议型 号:T11150产 地:中国大陆
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T11077Dopamine D2 receptor antagonist-1;多巴胺D2受体拮抗剂-1Dopamine D2 receptor antagonist-1
Dopamine D2 Receptor Antagonist-1 functions as a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R), demonstrating sub-millimolar affinity.
价 格:¥电议型 号:T11077产 地:中国大陆
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T11007LLevofloxacin Hydrochloride Impurity A;左氧氟沙星杂质A(盐酸盐)Levofloxacin Hydrochloride Impurity A(117707-40-1
Levofloxacin Hydrochloride Impurity A I, one of the quinolones, has a broad spectrum of antibacterial action.
价 格:¥电议型 号:T11007L产 地:中国大陆
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T10977DCEBIO;化合物DCEBIODCEBIO
DCEBIO stimulates the secretion of Cl- through the activation of the hIK1 K + channel and the activation of the apical Cl- conductance. DCEBIO is a derivative of 1-EBIO and a very strong activator of Cl- secretion by T84 colon cells.
价 格:¥电议型 号:T10977产 地:中国大陆
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T10877CPDA;化合物CPDACPDA
CPDA is a new potent inhibitor of SH2 domain-containing inositol phosphatase 2 (SHIP2).
价 格:¥电议型 号:T10877产 地:中国大陆
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T10820LCiraparantag TFA;化合物 T10820LPER977 TFA;PER977 TFA
Ciraparantag TFA is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoagulants.
价 格:¥电议型 号:T10820L产 地:中国大陆
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T10820Ciraparantag化合物 T10820PER977
Ciraparantag is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoagulants.
价 格:¥电议型 号:T10820产 地:中国大陆
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T1077LFluvoxamine;化合物 T1077LFluvoxamine
Fluvoxamine (DU-23000) is an antidepressant that acts pharmacologically as a selective serotonin reuptake inhibitor.
价 格:¥电议型 号:T1077L产 地:中国大陆
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T10779CGP 25454A;化合物 T10779CGP 25454A
CGP 25454A is a novel and selective antagonist of the presynaptic dopamine autoreceptor.
价 格:¥电议型 号:T10779产 地:中国大陆