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T18301Mal-Phe-C4-Val-Cit-PAB;化合物 T18301Mal-Phe-C4-Val-Cit-PAB
Mal-Phe-C4-Val-Cit-PAB is a cleavable antibody-drug conjugate (ADC) linker featuring a Maleimide functional group. It is employed in the synthesis of ADCs.
价 格:¥电议型 号:T18301产 地:中国大陆
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T18300Mal-Phe-C4-Val-Cit-PAB-DMEA;化合物 T18300Mal-Phe-C4-Val-Cit-PAB-DMEA|||Mal-Phe-C-4-Val-Cit-PAB-DMEA|||M
The chemical compound Mal-Phe-C4-Val-Cit-PAB-DMEA is a cleavable antibody-drug conjugate (ADC) linker that incorporates a Maleimide group. It is commonly employed in the synthesis of ADCs.
价 格:¥电议型 号:T18300产 地:中国大陆
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T1830BX795;化合物BX795BX795
BX795 is an effective and selective PDK1 inhibitor (IC50: 6 nM), and its selectivity is 140- and 1600-fold for PDK1 over PKA and PKC in cell-free assays, respectively. Meanwhile, the selectivity for PDK1 is 100-fold than GSK3β.
价 格:¥电议型 号:T1830产 地:中国大陆
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T18283Mal-PEG4-bis-PEG3-methyltetrazine;化合物 T18283Mal-PEG4-bis-PEG3-methyltetrazine
Mal-PEG4-bis-PEG3-methyltetrazine, a cleavable 7-unit PEG ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T18283产 地:中国大陆
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T18183m-PEG3-S-PEG4-propargyl;化合物 T18183m-PEG3-S-PEG4-propargyl
m-PEG3-S-PEG4-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18183产 地:中国大陆
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T18083m-PEG-azide (MW 2000);化合物 T18083m-PEG-azide (MW 2000)
m-PEG-azide (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18083产 地:中国大陆
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T1800GW788388;化合物GW 788388GW 788388;GW 788388
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.
价 格:¥电议型 号:T1800产 地:中国大陆
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T17983Fmoc-Val-Cit-PAB-MMAE;化合物Fmoc-Val-Cit-PAB-MMAEFmoc-Val-Cit-PAB-MMAE
Fmoc-Val-Cit-PAB-MMAE is consisted of the ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC.
价 格:¥电议型 号:T17983产 地:中国大陆
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T17883Pomalidomide-PEG3-C2-NH2;化合物Pomalidomide-PEG3-C2-NH2Cereblon Ligand-Linker Conjugates 5|||E3 ligase
Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide based cereblon ligand and 3-unit PEG linker.
价 格:¥电议型 号:T17883产 地:中国大陆
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T17839DNP-PEG4-DBCO;化合物 T17839DNP-PEG4-DBCO
DNP-PEG4-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17839产 地:中国大陆
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T17838DNP-PEG12-NHS ester;化合物 T17838DNP-PEG12-NHS ester
DNP-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17838产 地:中国大陆
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T17837DNP-PEG12-acid;化合物 T17837DNP-PEG12-acid
DNP-PEG12-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17837产 地:中国大陆
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T17836DMAC-SPP;化合物 T17836DMAC-SPP
DMAC-SPP is a cleavable linker vital in ADC synthesis. DMAC-SPP joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格:¥电议型 号:T17836产 地:中国大陆
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T17835DMAC-PDB;化合物 T17835DMAC-PDB
DMAC-PDB is a cleavable linker vital in ADC synthesis. DMAC-PDB joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格:¥电议型 号:T17835产 地:中国大陆
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T17834DM4-SPDP;化合物 T17834DM4-SPDP
DM4-SPDP, a drug-linker conjugate, integrates the antitubulin agent DM4 with the linker SMCC, facilitating the creation of antibody drug conjugates[1]. Additionally, SPDP serves as a short-chain crosslinker enabling amine-to-sulfhydryl conjugation, leveraging NHS-ester and pyridyldithiol groups to establish cleavable (reducible) disulfide bonds with cysteine sulfhydryls[2][3].
价 格:¥电议型 号:T17834产 地:中国大陆
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T17833DM4-SMCC;化合物 T17833DM4-SMCC
DM4-SMCC, a non-cleavable drug-linker conjugate for antibody-drug conjugates (ADC), leverages the antitumor efficacy of DM4 (an antitubulin agent) through attachment with the SMCC linker, exhibiting antitumor activity[1].
价 格:¥电议型 号:T17833产 地:中国大陆
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T17832DM1-PEG4-DBCO;化合物 T17832DM1-PEG4-DBCO
DM1-(PEG)4-DBCO is a drug-linker conjugate that combines the potent microtubulin inhibitor mertansine (DM1) with the DBCO-PEG4-Ahx linker for the development of antibody-drug conjugates (ADCs). This conjugation aims to mitigate the systemic toxicity associated with maytansine while improving tumor-specific delivery, leveraging DM1’s capabilities as an antibody-conjugatable maytansinoid.
价 格:¥电议型 号:T17832产 地:中国大陆
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T17831Dioxoisoindolin-O-PEG-OMe (MW 2000);化合物 T17831(1,3-dioxoisoindolin-2-yl)-O-PEG-OMe (MW 2000);(1,3-di
Dioxoisoindolin-O-PEG-OMe (MW 2000) is a polyethylene glycol (PEG) based PROTAC linker, which finds application in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17831产 地:中国大陆
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T17830Dioxoisoindolin-O-PEG-OH (MW 2000);化合物 T17830(1,3-dioxoisoindolin-2-yl)-O-PEG-OH (MW 2000);(1,3-diox
Dioxoisoindolin-O-PEG-OH (MW 2000) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of PROTACs (proteolysis targeting chimeras)[1].
价 格:¥电议型 号:T17830产 地:中国大陆
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T1783LXR-623;化合物LXR623LXR623|||WAY 252623;LXR623|||WAY 252623
LXR-623 (WAY 252623) is an orally bioavailable and highly specifical synthetic modulator of LXR.
价 格:¥电议型 号:T1783产 地:中国大陆