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T28897T-1095A;化合物 T28897T 1095A|||J1.265.331J;T 1095A|||J1.265.331J
T-1095A is an active metabolite of T-1095, a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs). Chronic administration of T-1095 (0.1% w w(-1) pellet chow, for 12 weeks) decreased blood glucose and haemoglobin A(1C) levels, and improved glucose intolerance in db/db mice. Long-term treatment with T-1095 causes sustained improvement in hyperglycemia and prevents diabetic neuropathy in Goto-Kakizaki Rats.
价 格:¥电议型 号:T28897产 地:中国大陆
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T28821SMR000071098;化合物 T28821SMR-000071098|||SMR 000071098;SMR-000071098|||SMR 000071098
SMR000071098 is an inhibitor of Fe-S cluster-dependent aconitase. SMR000071098 interacts with Suf proteins to inhibit iron-sulfur (Fe-S) cluster assembly.
价 格:¥电议型 号:T28821产 地:中国大陆
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T28431PNU109291;化合物 T28431PNU-109291|||PNU 109291;PNU-109291|||PNU 109291
PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.
价 格:¥电议型 号:T28431产 地:中国大陆
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T28267L(+)-ORM-10921;异构体ORM-10921(+)-ORM-10921
(+)-ORM-10921 is a conformation of ORM-10921 and can be used in chemical synthesis studies.
价 格:¥电议型 号:T28267L产 地:中国大陆
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T28267ORM-10921;化合物ORM-10921ORM10921|||ORM 10921;ORM10921|||ORM 10921
ORM-10921 is an α2C-adrenoceptor antagonist that has shown antipsychotic and antidepressant activity in animal studies.
价 格:¥电议型 号:T28267产 地:中国大陆
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T28109Contezolid;化合物 T28109MRX-I|||MRX I|||MRXI;MRX-I|||MRX I|||MRXI
MRX-I, a monoamine oxidase-A (MAO-A) Inhibitor, is used potentially for the treatment of acute bacterial skin.
价 格:¥电议型 号:T28109产 地:中国大陆
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T28098MRS1097;化合物 T28098MRS-1097|||MRS 1097;MRS-1097|||MRS 1097
MRS1097 is a selective antagonist A3 adenosine receptor.
价 格:¥电议型 号:T28098产 地:中国大陆
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T27964Voxvoganan;化合物 T27964LTX109|||Lytixar|||LTX-109|||LTX 109;LTX109|||Lytixar|||LTX-109|||LTX 109
Lytixar is a Synthetic Antimicrobial Peptide, it shows activity against Daptomycin-Nonsusceptible, Methicillin-Resistant, Vancomycin-Intermediate, Vancomycin-Resistant, and Linezolid-Nonsusceptible Staphylococcus aureus. LTX-109 demonstrated a MIC range of 2 to 4 μg/ml and dose-dependent rapid bactericidal activity against S. aureus. This activity was not influenced by resistance to other antistaphylococcal agents.
价 格:¥电议型 号:T27964产 地:中国大陆
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T27960LY-510929;化合物 T27960LY 510929|||LY-929|||LY 929|||LY929|||LY510929;LY 510929|||LY-929|||LY 929|||LY9
LY-510929, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of hyperlipidaemia, metabolic disorders and type 2 diabetes.
价 格:¥电议型 号:T27960产 地:中国大陆
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T27752KT109化合物 T27752KT-109|||KT 109
KT109 is a selective inhibitor of DAGLβ (IC50 = 42 nM). KT109-treated wild-type mice displayed reductions in LPS-induced allodyni as well as in DAGL-β (-/-) micea. Repeated KT109 administration prevented the expression of LPS-induced allodynia, without evidence of tolerance. Intraplantar injection of KT109 into the LPS-treated paw, but not the contralateral paw, reversed the allodynic responses. KT109 also reversed allodynia in the CCI and CINP models and lacked discernible side effects (e.g. an
价 格:¥电议型 号:T27752产 地:中国大陆
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T27747KRP-109;化合物 T27747KRP 109|||KRP109;KRP 109|||KRP109
KRP-109, a neutrophil elastase (NE) inhibitor, acts by decreasing expression of TGF-? Signal Related Genes.
价 格:¥电议型 号:T27747产 地:中国大陆
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T27696JTK-109;化合物JTK-109JTK109;JTK109
JTK-109 is an inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor and inhibits G1b and G3a subgenomic replicons and recombinant enzymes.
价 格:¥电议型 号:T27696产 地:中国大陆
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T27669JNJ-26070109;化合物 T27669JNJ26070109;JNJ26070109
JNJ-26070109, an antagonist of cholecystokinin CCK2 receptor, inhibits gastric acid secretion and prevents omeprazole-induced acid rebound in the rat.
价 格:¥电议型 号:T27669产 地:中国大陆
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T27217Duazomycin;化合物 T27217Duazomycin A|||Acetyl-don|||Diazomycin A|||NSC 51097;Duazomycin A|||Acetyl-don|
Duazomycin, an antitumor substance and glutamine antagonist, is used as a chemotherapeutic agent.
价 格:¥电议型 号:T27217产 地:中国大陆
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T27118DAA-1097;化合物 T27118DAA-1097
DAA-1097 is a novel ligand of peripheral benzodiazepine receptor.
价 格:¥电议型 号:T27118产 地:中国大陆
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T27109CYP1A1 inhibitor 8a;化合物 T27109CYP1A1 inhibitor 8a
CYP1A1 inhibitor 8a is a potent and selective CYP1A1 inhibitor. It antagonizes B[a]P mediated activation of aromatic hydrocarbon receptor (AhR) in yeast cells, thereby protects human cells from CYP1A1-mediated B[a]P toxicity.
价 格:¥电议型 号:T27109产 地:中国大陆
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T26826Bisindolylmaleimide I HCl化合物 T26826GF-109203X HCl|||BIS-I HCl|||GO-6860 HCl
Bisindolylmaleimide I HCl is a specific ATP-competitive PKC inhibitor.
价 格:¥电议型 号:T26826产 地:中国大陆
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T26604Alvameline Tartrate;化合物 T26604LU-25-109T|||LU 25 109T|||LU-25109T|||LU 25109T;LU-25-109T|||LU 25 109
Alvameline Tartrate, a muscarinic M1 receptor agonist and M2/M3 receptor antagonist, is used potentially for treatment of urinary incontinence.
价 格:¥电议型 号:T26604产 地:中国大陆
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T26109Robenacoxib;罗贝考昔Onsior;Onsior
Robenacoxib (Onsior) is a non-steroidal compound with strong selectivity for cyclooxygenase-2 and anti-inflammatory activity.
价 格:¥电议型 号:T26109产 地:中国大陆
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T26033RAC 109;化合物 T26033RAC-109|||RAC109;RAC-109|||RAC109
RAC 109 is a chiral antiarrhythmic agent.
价 格:¥电议型 号:T26033产 地:中国大陆