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T39972EB-42486
EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.
价 格:¥电议型 号:T39972产 地:中国大陆
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T3979Emedastine依美斯汀;Emadine;LY188695
Emedastine is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its downstream activity. As a result this agent i
价 格:¥电议型 号:T3979产 地:中国大陆
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T39789BMS-986235LAR-1219;BMS-986235
BMS-986235 (LAR-1219) is a selective, orally active formyl peptide receptor 2 (FPR2) agonist, with EC 50 s of 0.41 nM and 3.4 nM for hFPR2 and mFPR2, respectively. BMS-986235 has potential for the prevention of heart failure.
价 格:¥电议型 号:T39789产 地:中国大陆
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T3978LinerixibatIinerixibat;GSK2330672
GSK2330672 is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties.
价 格:¥电议型 号:T3978产 地:中国大陆
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T3977Lifitegrast立他司特;利非司特;SAR 1118;SHP-606
Lifitegrast is a lymphocyte, function-associated antigen-1 antagonist.
价 格:¥电议型 号:T3977产 地:中国大陆
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T3976Cytosporone BCsn-B;Dothiorelone G
Cytosporone B is a naturally occurring agonist for the nuclear receptor Nur77 (IC50 = 0.278 nM). Activation of Nur77 with cytosporone B induces the expression of Nur77-dependent genes, including the gene for Nur77 itself. Signaling through Nur77 induces a
价 格:¥电议型 号:T3976产 地:中国大陆
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T3975AZD9496
AZD9496 is an orally available selective estrogen receptor(ERα) antagonist, with potential antineoplastic activity.
价 格:¥电议型 号:T3975产 地:中国大陆
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T39738ASP2453ASP2453
ASP2453 is a potent, selective and covalent KRAS G12C inhibitor. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC 50 value of 40 nM.
价 格:¥电议型 号:T39738产 地:中国大陆
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T3973PF-CBP1
PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP). It inhibits CREBBP (IC50: 125 nM) and p300 bromodomains (IC50: 363 nM).
价 格:¥电议型 号:T3973产 地:中国大陆
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T3972SR-3029SR3029;SR 3029
SR 3029 is a potent and highly specific CK1δ/CK1ε inhibitor.
价 格:¥电议型 号:T3972产 地:中国大陆
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T39710ARV-471
ARV-471 is a best-in-class, orally active Cereblon -based estrogen receptor ( ER ) PROTAC degrader. ARV-471 is developed for the research of breast cancer [1] .
价 格:¥电议型 号:T39710产 地:中国大陆
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T3971CASINPirl1-related Compound 2
CASIN is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).
价 格:¥电议型 号:T3971产 地:中国大陆
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T39233SIRT7 inhibitor 97491
SIRT7 inhibitor 97491 is an HDAC inhibitor with high specificity for SIRT7 (IC50 = 325 nM). SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.
价 格:¥电议型 号:T39233产 地:中国大陆
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T3897Isoschaftoside
Isoschaftoside is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Isoschaftoside has anti-tumor, antioxidant, and antimicrobial activities, it also
价 格:¥电议型 号:T3897产 地:中国大陆
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T38423CL097CL097
CL097, a potent TLR7/8 agonist, induces pro-inflammatory cytokines in macrophages. CL097 induces NADPH oxidase priming, resulting in an increase of the fMLF-stimulated ROS production.
价 格:¥电议型 号:T38423产 地:中国大陆
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T38050CP-609754
CP-609754 shows selective inhibition of farnesyltransferase.
价 格:¥电议型 号:T38050产 地:中国大陆
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T3797IsosilybinIsosilibinin;Silybin B;Silymarin;Isosilybinin;Q-100795;异水飞蓟宾
Isosilybin and Silybin might be suitable candidates to design potent PXR antagonists to prevent drug-drug interactions via CYP3A4 in cancer patients.
价 格:¥电议型 号:T3797产 地:中国大陆
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T37504LCathepsin D and E FRET Substrate acetate(839730-93-7 Free base)Cathepsin D and E FRET Substrate acet
Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E but not for B, H, or L. Cathepsin D and E FRET Substrate acetate can be used in mechanistic studies on cathepsins D and E studies.
价 格:¥电议型 号:T37504L产 地:中国大陆
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T3716RolapitantSCH619734;罗拉吡坦;罗拉匹坦
Rolapitant Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitiv
价 格:¥电议型 号:T3716产 地:中国大陆