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T77117Toripalimab;化合物 ToripalimabToripalimab
Toripalimab, the first domestic anti-tumor PD-1 antibody in China, is a selective, recombinant, humanized monoclonal antibody that targets PD-1. By binding to PD-1, it inhibits interactions with its ligands, demonstrating primary anti-tumor efficacy in various tumors, including melanoma, lung cancer, digestive tract tumors, hepatobiliary and pancreatic tumors, neuroendocrine neoplasms, nasopharyngeal carcinoma, and urothelial carcinoma [1].
价 格:¥电议型 号:T77117产 地:中国大陆
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T77116Plonmarlimab;化合物 PlonmarlimabPlonmarlimab
Plonmarlimab (TJ003234), an anti-GM-CSF monoclonal antibody, is utilized in researching rheumatoid arthritis and COVID-19 [1] [2].
价 格:¥电议型 号:T77116产 地:中国大陆
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T77115Plamotamab;化合物 PlamotamabPlamotamab
Plamotamab (XmAb-13676), a human bispecific antibody (bsAb) targeting CD3 and CD20, recruits cytotoxic T cells to eliminate CD20-expressing tumor cells. It demonstrates mild hematologic reaction (MR) and effectively induces tumor regression in vivo [1] [2].
价 格:¥电议型 号:T77115产 地:中国大陆
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T77114Placulumab;化合物 PlaculumabPlaculumab
Placulumab (ART621), an anti-TNF α monoclonal antibody, possesses anti-inflammatory properties with potential applications in treating inflammatory diseases, such as arthritis [1].
价 格:¥电议型 号:T77114产 地:中国大陆
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T77113Ongericimab;化合物 OngericimabOngericimab
Ongericimab (JS002) is a humanized monoclonal antibody targeting PCSK9 with demonstrated lipid-lowering efficacy. It is utilized in the research of hypercholesterolemia and hyperlipidemia [1].
价 格:¥电议型 号:T77113产 地:中国大陆
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T77111Omodenbamab;化合物 OmodenbamabOmodenbamab
Omodenbamab, a humanized monoclonal antibody targeting Staphylococcal protein A (SpA), exhibits a dissociation constant (K D) of 0.0467 nM, effectively countering a crucial S. aureus evasion strategy by focusing on the cell wall component Protein A (SpA). It is applicable in the study of S. aureus bloodstream infections [1].
价 格:¥电议型 号:T77111产 地:中国大陆
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T77110Amivantamab;化合物 AmivantamabAmivantamab
Amivantamab (JNJ-61186372) is a bispecific antibody targeting EGFR-MET with immune anticancer properties. It prevents ligand binding, enhances receptor-antibody complex endocytosis and degradation, and triggers Fc-mediated macrophage cytokinesis and natural killer cell antibody-dependent cytotoxicity [1].
价 格:¥电议型 号:T77110产 地:中国大陆
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T77108Olinvacimab;化合物 OlinvacimabOlinvacimab
Olinvacimab (TTAC-0001), a fully human anti-VEGFR2 monoclonal antibody, demonstrates antiangiogenic activity by inhibiting VEGF binding to KDR, with a dissociation constant (K d) of 0.23 nM. It is utilized in research for treating recurrent glioblastoma and breast cancer [1].
价 格:¥电议型 号:T77108产 地:中国大陆
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T77107Olendalizumab;化合物 OlendalizumabOlendalizumab
Olendalizumab (ALXN1007), a humanized IgG2-G4-κ antibody derived from mice, specifically targets Complement protein C5a with a binding affinity (K i) of 60 pM. This compound is designed to inhibit the complement inflammatory pathway. Additionally, olendalizumab is utilized in the research of complement-mediated disorders triggered by the coronavirus [1] [2].
价 格:¥电议型 号:T77107产 地:中国大陆
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T77106Odulimomab;化合物 OdulimomabOdulimomab
Odulimomab (anti-LFA1), an anti-LFA-1 monoclonal antibody, inhibits T lymphocyte proliferation and provides protection against ischemia and reperfusion injury. It is utilized in researching transplant rejection and immunological diseases [1] [2].
价 格:¥电议型 号:T77106产 地:中国大陆
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T77105Odesivimab;化合物 OdesivimabOdesivimab
Odesivimab, a humanized monoclonal antibody, targets the Ebola virus glycoprotein, exhibiting a binding affinity (K D value) of 7.74 nM for the recombinant histidine-tagged ectodomain of the Makona strain Ebola virus glycoprotein. It is applicable in the research of Ebola virus infection [1].
价 格:¥电议型 号:T77105产 地:中国大陆
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T77104Obrindatamab;化合物 ObrindatamabObrindatamab
Obrindatamab, a humanized anti-B7-H3/CD3 bispecific antibody, targets B7-H3 and CD3, facilitating redirected cytotoxic T-lymphocyte (CTL) activity towards B7-H3-expressing cancer cells. It is utilized in cancer research [1].
价 格:¥电议型 号:T77104产 地:中国大陆
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T77103Nurulimab;化合物 NurulimabNurulimab
Nurulimab (BCD-145) is a humanized monoclonal antibody targeting cytotoxic T lymphocyte antigen-4 (anti-CTLA-4). It has potential applications in melanoma research [1].
价 格:¥电议型 号:T77103产 地:中国大陆
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T77102Nofazinlimab;化合物 NofazinlimabNofazinlimab
Nofazinlimab (CS1003), a humanized IgG4 anti-PD-1 monoclonal antibody, is employed in research for unresectable hepatocellular carcinoma (uHCC) [1].
价 格:¥电议型 号:T77102产 地:中国大陆
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T77101Nivatrotamab;化合物 NivatrotamabNivatrotamab
Nivatrotamab (Hu3F8-BsAb), a humanized anti-GD2/CD3 bispecific antibody and T-cell engager specific to CD3 and GD2, is employed in the study of neuroblastoma [1].
价 格:¥电议型 号:T77101产 地:中国大陆
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T77100Nirsevimab尼塞韦单抗MEDI8897
Nirsevimab (MEDI8897) is a recombinant human respiratory syncytial virus (RSV) monoclonal antibody with a modified Fc region. Nirsevimab efficiently targets RSV-B with a Kd value of 1.5 nM. Nirsevimab can be used to prevent RSV infection.
价 格:¥电议型 号:T77100产 地:中国大陆
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T77099Nimacimab;尼迈西单抗JNJ 2463|||RYI-018;JNJ 2463|||RYI-018
Nimacimab is a recombinant humanized monoclonal antibody. It can improve diabetes and non-alcoholic steatohepatitis.
价 格:¥电议型 号:T77099产 地:中国大陆
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T77098Netakimab;化合物 NetakimabNetakimab
Netakimab, an anti-IL-17 monoclonal antibody, is utilized in the research of ankylosing spondylitis, psoriatic arthritis, and moderate-to-severe plaque psoriasis [1] [2].
价 格:¥电议型 号:T77098产 地:中国大陆
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T77097Nerelimomab;化合物 NerelimomabNerelimomab
Nerelimomab (BAYX1351), an anti-TNF-α antibody, is utilized in sepsis research [1] [2].
价 格:¥电议型 号:T77097产 地:中国大陆
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T77095Nebacumab;化合物 NebacumabNebacumab
Nebacumab (HA-1A), a monoclonal antibody, targets the lipid A component of endotoxin and has potential applications in sepsis research [1] [2].
价 格:¥电议型 号:T77095产 地:中国大陆