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T10778CGP 20712 A；化合物 CGP 20712 ACGP 20712 mesylate；CGP 20712 mesylate
CGP 20712 A (CGP 20712 mesylate) is a selective and potent β1-adrenergic receptor antagonist (IC50: 0.7 nM) with antihypertensive activity that reverses RKT-induced gastric relaxation.
价 格：￥电议型 号：T10778产 地：中国大陆
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T10776CFTR corrector 4；CFTR 校正剂 4CFTR corrector 4
CFTR corrector 4 is a potent and orally available transmembrane conductance regulator (CFTR) for cystic fibrosis and is a potent (R,R) type active enantiomer. CFTR corrector 4 increases CFTR levels on the cell surface and is a potential compound for the study of cystic fibrosis.
价 格：￥电议型 号：T10776产 地：中国大陆
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T10775c-Fms-IN-2；化合物c-Fms-IN-2c-Fms-IN-2
c-Fms-IN-2 is an inhibitor of c-FMS kinase (IC50 = 24 nM).
价 格：￥电议型 号：T10775产 地：中国大陆
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T10774CFM-2；化合物CFM-2CFM-2
CFM-2, a potent and selective non-competitive antagonist of AMPAR (AMPAR), exhibits anticonvulsant activity across various seizure models.
价 格：￥电议型 号：T10774产 地：中国大陆
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T10773CF53；化合物CF53CF53
CF53 is a highly potent, selective and orally active inhibitor of BET protein, with a Ki of <1 nM, Kd of 2.2 nM and an IC50 of 2 nM for BRD4 BD1. CF53 binds to both the BD1 and BD2 domains of BRD2, BRD3, BRD4, and BRDT BET proteins with high affinities, very selective over non-BET bromodomain-containing proteins. CF53 shows potent anti-tumor activity both in vitro and in vivo.
价 格：￥电议型 号：T10773产 地：中国大陆
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T10772LCevipabulin fumarate化合物 T10772LTTI-237 fumarate
Cevipabulin (TTI-237) fumarate is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell line).
价 格：￥电议型 号：T10772L产 地：中国大陆
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T10772Cevipabulin；西维布林TTI-237；TTI-237
Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell line).
价 格：￥电议型 号：T10772产 地：中国大陆
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T10771CETP-IN-3；化合物 T10771CETP-IN-3
CETP-IN-3 is an inhibitor of the plasma glycoprotein cholesterol ester transfer protein (CETP), elevating HDL-C through inhibition of CETP.
价 格：￥电议型 号：T10771产 地：中国大陆
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T10770Cetirizine D8；化合物 T10770Cetirizine D8
Cetirizine D8 is a deuterium-labeled Cetirizine. Cetirizine is a second-generation antihistamine and a long-acting histamine H1-receptor antagonist.
价 格：￥电议型 号：T10770产 地：中国大陆
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T1077Fluvoxamine maleate；氟伏沙明马来酸盐MK-264|||DU-23000 (maleate)；氟伏沙明马来酸盐|||马来酸氟伏沙明|||MK-264|||DU-23000 (male
Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders.
价 格：￥电议型 号：T1077产 地：中国大陆
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T10677Carbodine；化合物 T10677Carbodine
Carbodine (Carbocyclic cytidine) is a broad-spectrum antiviral agent and targets CTP synthetase that converts UTP to CTP. It possesses significant antiviral activity against influenza virus types A0/PR-8/34 and A2/Aichi/2/68 in vitro.
价 格：￥电议型 号：T10677产 地：中国大陆
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T10590Zatolmilast；化合物BPN14770BPN14770；BPN14770
Zatolmilast (BPN14770) is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).
价 格：￥电议型 号：T10590产 地：中国大陆
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T10577BM 957；化合物 T10577BM 957
BM 957 is an effective Bcl-2 and Bcl-xL inhibitor (Kis: 1.2 and <1 nM; IC50s: 5.4 and 6.0 nM).
价 格：￥电议型 号：T10577产 地：中国大陆
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T10477BAY-985；化合物BAY-985BAY-985
BAY-985 is a potent, selective, and orally active ATP-competitive dual inhibitor of TBK1 and IKKε (IC50s: 2/30 and 2 nM for TBK1 (low/high ATP) and IKKε) with antitumor efficacy.
价 格：￥电议型 号：T10477产 地：中国大陆
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T10473LBAY-677；化合物 T10473LBAY-677
BAY-677, serving as an inactive control for BAY-678, is distinguished by BAY-678´s capabilities as an orally bioavailable, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE), showcasing a high potency with an IC50 of 20 nM[1]. Furthermore, BAY-678 has been publicly nominated as a chemical probe by the Structural Genomics Consortium (SGC)[2].
价 格：￥电议型 号：T10473L产 地：中国大陆
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T10471BAY 60-2770；化合物 T10471BAY 60-2770
BAY 60-2770 is a selective and orally active soluble guanylyl cyclase (sGC) activator with antifibrotic effect. It increases the activity of sGC in a nitric oxide-independent manner.
价 格：￥电议型 号：T10471产 地：中国大陆
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T10406Tuvusertib；化合物TuvusertibM1774|||ATR inhibitor 1；M1774|||ATR inhibitor 1
Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 ?Μ) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks downstream phosphorylation of serine/threonine protein kinase checkpoint kinase 1 (CHK1), thereby inhibits DNA damage checkpoint activation, disrupting DNA damage repair and inducing apoptosis in tumor cells.
价 格：￥电议型 号：T10406产 地：中国大陆
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T10377Artefenomel；化合物 T10377OZ439；OZ439
Artefenomel (OZ439) is a synthetic antimalarial agent with the artemisinin pharmacophore.
价 格：￥电议型 号：T10377产 地：中国大陆
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T10370ARN 077化合物 T10370URB913
ARN 077 is a selective N-acylethanolamine acid amidase (NAAA) inhibitor (IC50: 7 nM for human NAAA). ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS.
价 格：￥电议型 号：T10370产 地：中国大陆
