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T16878SHP836;化合物 T16878SHP836
SHP836 is an inhibitor of SHP2 allosteric (IC50: 12 μM for the full-length SHP2).
价 格:¥电议型 号:T16878产 地:中国大陆
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T16856SB228357;化合物SB228357SB228357
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.
价 格:¥电议型 号:T16856产 地:中国大陆
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T16838Saikogenin A;柴胡皂苷元ASaikogenin A
Saikogenin A is a dipeptidyl peptidase-4 inhibitor.
价 格:¥电议型 号:T16838产 地:中国大陆
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T16837SAICAR;化合物 T16837SAICAR
SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner (EC50: 0.3 mM).
价 格:¥电议型 号:T16837产 地:中国大陆
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T16836SAFit2;化合物SAFit2SAFit2
SAFit2 is a highly effective and selective fk506 binding protein 51(FKBP51) inhibitor (Ki: 6 nM). SAFit2 can enhance AKT2-AS160 binding and participate in the downstream response of glucocorticoid release in vivo, and is a candidate compound for the treatment of obesity, chronic pain, depression and anxiety.
价 格:¥电议型 号:T16836产 地:中国大陆
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T16835SAFit1;化合物 T16835SAFit1
SAFit1 is an inhibitor of FK506 binding protein 51 (FKBP51)-specific (Ki: 4±0.3 nM).
价 格:¥电议型 号:T16835产 地:中国大陆
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T16834S26131;化合物S26131N-[2-[7-[3-[8-(2-acetamidoethyl)naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]ace
S26131 (N-[2-[7-[3-[8-(2-acetamidoethyl)naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]acetamide) behaves as an antagonist on MT1 and MT2 receptors with Ki of 0.5 and 112 nM respectively.
价 格:¥电议型 号:T16834产 地:中国大陆
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T16833S1P1 Agonist III;化合物 T16833S1P1 Agonist III
S1P1 Agonist III is an effective and orally active S1P1 agonist (EC50: 18 nM).
价 格:¥电议型 号:T16833产 地:中国大陆
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T16832S18-000003;化合物S18-000003S18-000003
S18-000003 is an effective orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t inhibitor (IC50: 29 nM). S18-000003 inhibits IL-17 production.
价 格:¥电议型 号:T16832产 地:中国大陆
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T16831(S)-SNAP5114;化合物(S)-SNAP5114(S)-SNAP5114
(S)-SNAP5114 is a selective inhibitor of GABA transport with IC50s of 5 μM for hGAT-3 and 21 μM for rGAT-2. (S)-SNAP5114 has anticonvulsant properties.
价 格:¥电议型 号:T16831产 地:中国大陆
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T16830S-MTC;化合物 T16830S-MTC
S-MTC is a selective inhibitor of type I nitric oxide synthase.
价 格:¥电议型 号:T16830产 地:中国大陆
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T1683Actriol;异雌三醇Epiestriol;异雌三醇|||Epiestriol
Actriol (Epiestriol) is always used as Glucocorticoid Receptor agonist.
价 格:¥电议型 号:T1683产 地:中国大陆
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T16803RS 8359;化合物RS 8359RS 8359
RS 8359 is a reversible inhibitor of monoamine oxidase A (MAO-A) with a selectivity ratio of about 2200 for the A:B enzyme types. RS 8359 has antidepressant activity.
价 格:¥电议型 号:T16803产 地:中国大陆
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T16783Rolziracetam;罗拉西坦CI-911;罗拉西坦|||CI-911
Rolziracetam (CI-911) is a nootropic drug of the racetam family. It can improve short-term memory in rats and monkeys.
价 格:¥电议型 号:T16783产 地:中国大陆
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T16696Pyriproxyfen;吡丙醚S-31183;S-31183|||吡丙醚
Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.
价 格:¥电议型 号:T16696产 地:中国大陆
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T16683Pumosetrag Hydrochloride化合物 T16683MKC-733|||DDP-733
Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.
价 格:¥电议型 号:T16683产 地:中国大陆
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T16583Propargyl-PEG1-acid;化合物 T16583Propargyl-PEG1-acid
Propargyl-PEG1-acid, a PEG-based PROTAC linker, enables the synthesis of BTK-CRBN PROTACs, specifically Ibrutinib-based PROTAC 4 and PROTAC 5. At a concentration of 10 μM, PROTAC 5 facilitates the degradation of BTK and induces the degradation of CSK, LYN, and LAT2[1].
价 格:¥电议型 号:T16583产 地:中国大陆
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T16523LPhiKan 083;化合物PhiKan 083PhiKan 083
PhiKan 083 is a carbazole derivative
价 格:¥电议型 号:T16523L产 地:中国大陆
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T16523PhiKan 083 hydrochloride化合物 T16523PhiKan 083 hydrochloride
PhiKan 083 hydrochloride is a carbazole derivative. Which binds to the surface cavity and stabilizes Y220C (Kd: 167 μM). It also a relative binding affinity (Kd) of 150 μM in Ln229 cells.
价 格:¥电议型 号:T16523产 地:中国大陆