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T16514PF 04531083；化合物PF 04531083PF 04531083
PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.
价 格：￥电议型 号：T16514产 地：中国大陆
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T16503PF-4191834；化合物PF-4191834PF-04191834；PF-04191834
PF-4191834 is a noniron chelating and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) with an IC50 of 229 nM. PF-4191834 shows ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX and displays no activity toward the cyclooxygenase enzymes. PF-4191834
价 格：￥电议型 号：T16503产 地：中国大陆
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T16483PF-05105679；化合物PF-05105679PF-05105679
PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.
价 格：￥电议型 号：T16483产 地：中国大陆
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T16383Olinciguat；化合物OlinciguatIW-1701；IW-1701
Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole-cell assay.
价 格：￥电议型 号：T16383产 地：中国大陆
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T16283Neocarzinostatin；化合物 T16283Neocarzinostatin
Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic. It recognizes double-stranded DNA bulge and induces DNA double strand breaks (DSBs). Neocarzinostatin leads to apoptosis. Neocarzinostatin has potential for EpCAM-positive cancer treatment.
价 格：￥电议型 号：T16283产 地：中国大陆
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T16275NB001；化合物NB001HTS 09836；HTS 09836
NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.
价 格：￥电议型 号：T16275产 地：中国大陆
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T1619Trazodone hydrochloride；盐酸曲唑酮KB-831|||Trazodone HCl|||AF-1161；KB-831|||盐酸曲唑酮|||Trazodone HCl|||AF-11
Trazodone hydrochloride (Trazodone HCl) is a serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety.
价 格：￥电议型 号：T1619产 地：中国大陆
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T16183N-(Azido-PEG2)-N-Fluorescein-PEG3-acid；化合物 T16183N-(Azido-PEG2)-N-Fluorescein-PEG3-acid
N-(Azido-PEG2)-N-Fluorescein-PEG3-acid is a polyethylene glycol (PEG)-derived PROTAC linker specifically designed for the synthesis of PROTACs[1].
价 格：￥电议型 号：T16183产 地：中国大陆
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T16100Balamapimod；化合物 T16100MKI 833；MKI 833
Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.
价 格：￥电议型 号：T16100产 地：中国大陆
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T16097MK-8318；化合物 T16097MK-8318
MK-8318 is an effective and selective antagonist of the CRTh2 receptor (Ki: 5.0 nM).
价 格：￥电议型 号：T16097产 地：中国大陆
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T16083Mizagliflozin；化合物MizagliflozinGSK-1614235 free base|||KGA-3235 free base|||DSP-3235 free base；GSK-16
Mizagliflozin (GSK-1614235 free base) is a sodium-glucose transporter inhibitor( Ki of 27 nM for human SGLT1). Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation.
价 格：￥电议型 号：T16083产 地：中国大陆
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T15983Mal-PEG2-PFP ester；化合物 T15983Mal-PEG2-PFP ester
Mal-PEG2-PFP ester, an alkyl/ether-based PROTAC linker, facilitates the synthesis of PROTACs.
价 格：￥电议型 号：T15983产 地：中国大陆
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T15839m-PEG12-amine；化合物m-PEG12-aminem-PEG12-amine
m-PEG12-amine is a PEG-based PROTAC linker and a non-cleavable 12 unit PEG ADC linker employed in the synthesis of PROTACs[1] and antibody-drug conjugates (ADCs)[2].
价 格：￥电议型 号：T15839产 地：中国大陆
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T15838m-PEG11-Amine；化合物 T15838m-PEG11-Amine
m-PEG11-Amino is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T15838产 地：中国大陆
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T15837m-PEG10-Tos；化合物 T15837m-PEG10-Tos
m-PEG10-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T15837产 地：中国大陆
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T15836m-PEG10-azide；化合物 T15836m-PEG10-azide
m-PEG10-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T15836产 地：中国大陆
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T15835m-PEG10-amine；化合物 T15835m-PEG10-amine
m-PEG10-amine is a 10-unit polyethylene glycol (PEG) linker that is non-cleavable. It serves as an essential component in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, m-PEG10-amine functions as a PEG-based linker in the synthesis of PROTACs[1], effectively facilitating their formation.
价 格：￥电议型 号：T15835产 地：中国大陆
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T15834m-PEG10-alcohol；化合物 T15834Decaethylene glycol monomethyl ether；Decaethylene glycol monomethyl ether
m-PEG10-alcohol, also known as Decaethylene glycol monomethyl ether, is a non-cleavable 10 unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, m-PEG10-alcohol serves as a PEG-based PROTAC linker, enabling its application in the synthesis of PROTACs[1].
价 格：￥电议型 号：T15834产 地：中国大陆
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T15833m-PEG1-NHS ester；化合物 T15833m-PEG1-NHS ester
m-PEG1-NHS ester, a polyethylene glycol (PEG)/alkyl/ether-based PROTAC linker, is utilized for the synthesis of PROTACs.
价 格：￥电议型 号：T15833产 地：中国大陆
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T15831M-525；化合物 T15831M-525
M-525 binds to menin (IC50: 3 nM) and achieves low nanomolar potencies in cell growth inhibition and in the suppression of MLL regulated gene expression in MLL leukemia cells. M-525 is a first-in-class, highly potent, irreversible, and covalent menin-MLL protein-protein interaction inhibitor. It has an Anti-leukemia activity.
价 格：￥电议型 号：T15831产 地：中国大陆
