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T15830M-110;化合物M-110M-110
M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC50=47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 μM. M-110 inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 μM.
价 格:¥电议型 号:T15830产 地:中国大陆
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T1583Vorinostat伏立诺他MK0683|||伏立诺他|||suberoylanilide hydroxamic acid|||SAHA
Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11. Vorinostat has antitumor activity, induces cell differentiation, blocks the cell cycle and induces apoptosis.
价 格:¥电议型 号:T1583产 地:中国大陆
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T15793Lurbinectedin;卢比克替定PM01183;卢比克替定|||PM01183
Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.
价 格:¥电议型 号:T15793产 地:中国大陆
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T15783LP117;化合物 T15783LP117
LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).
价 格:¥电议型 号:T15783产 地:中国大陆
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T15767LLY-283;化合物LLY-283LLY-283
LLY-283 is a potent, selective and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 22 nM and a Kd of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity.
价 格:¥电议型 号:T15767产 地:中国大陆
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T15754Lidanserin;化合物 T15754ZK-33839;ZK-33839
Lidanserin is an antagonist of the 5-HT2A and α1-adrenergic receptor.
价 格:¥电议型 号:T15754产 地:中国大陆
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T15747Lexithromycin;来红霉素Erythromycin A 9-methoxime|||Wy 48314;Erythromycin A 9-methoxime|||Wy 48314|||来红霉素
Lexithromycin is an erythromycin A derivative. It has antibacterial activity.
价 格:¥电议型 号:T15747产 地:中国大陆
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T15688L-771688;化合物L-771688SNAP 6383;SNAP 6383
L-771688 (SNAP 6383) is a novel potent and selective α1A-adrenoceptor antagonist with a Ki value of 0.43±0.02 nM.L-771688 KE is used for the treatment of benign prostatic hyperplasia.
价 格:¥电议型 号:T15688产 地:中国大陆
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T15683L-689502;化合物 T15683L-689502
L-689502 is a potent HIV-l protease inhibitor (IC50: 1 nM).
价 格:¥电议型 号:T15683产 地:中国大陆
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T15654Ketohexokinase inhibitor 1;化合物Ketohexokinase inhibitor 1PF-06835919;PF-06835919
Ketohexokinase inhibitor 1 is a ketohexokinase inhibitor (IC50s: 8.4 nM and 66 nM for KHK-C and KHK-A, respectively).
价 格:¥电议型 号:T15654产 地:中国大陆
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T15613JHU-083;化合物 T15613JHU-083
JHU-083 is a selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b+ cells. JHU-083 also experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals.
价 格:¥电议型 号:T15613产 地:中国大陆
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T15583GSK 3008348 hydrochloride;化合物 T15583GSK 3008348 hydrochloride
GSK 3008348 hydrochloride is an integrin αvβ6 antagonist. The affinity (pIC50) for the human - a 6 protein in the Fluorescence Polarisation Assay for GSK 3008348 is 8.1, whereas its affinity in the cell Adhesion Assays was for ανβ6 (pIC50: 8.4); ανβ3 (pIC50: 6); ανβ5 (pIC50: 6.9); ανβ8 (pIC50: 7.7).
价 格:¥电议型 号:T15583产 地:中国大陆
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T15565Imetit dihydrobromide化合物 T15565VUF 8325 dihydrobromide|||SKF 91105 dihydrobromide
Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).
价 格:¥电议型 号:T15565产 地:中国大陆
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T15483LEDGIN6;化合物 T15483HIV-1 integrase inhibitor 2;HIV-1 integrase inhibitor 2
HIV-1 integrase inhibitor 2 is used for the treatment of human immunodeficiency virus (HIV) infection.
价 格:¥电议型 号:T15483产 地:中国大陆
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T15436GSK2838232;化合物GSK2838232GSK2838232
GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,GSK2838232 is novel human immune virus (HIV) maturation inhibitor.
价 格:¥电议型 号:T15436产 地:中国大陆
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T15435GSK2837808A;化合物GSK2837808AGSK2837808A
GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).
价 格:¥电议型 号:T15435产 地:中国大陆
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T15418GS-6201;化合物GS-6201CVT-6883;CVT-6883
GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors with a Ki of 22 nM.
价 格:¥电议型 号:T15418产 地:中国大陆
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T15383Glesatinib hydrochloride;化合物 T15383MGCD265 hydrochloride;MGCD265 hydrochloride
Glesatinib hydrochloride is an orally active and potent dual inhibitor of MET/SMO. Glesatinib hydrochloride is also a tyrosine kinase inhibitor. It antagonizes P-glycoprotein mediated multidrug resistance (MDR) in NSCLC.
价 格:¥电议型 号:T15383产 地:中国大陆
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T15367Gadoxetate Disodium;钆塞酸二钠Gd-EOB-DTPA Disodium|||ZK 139834;Gd-EOB-DTPA Disodium|||钆塞酸二钠|||ZK 139834
Gadoxetate Disodium is used to evaluate focal liver lesions, such as hepatocellular carcinoma or liver metastasis on T1-weighted imaging. It is a contrast agent in magnetic resonance imaging (MRI) of the hepatobiliary system. It accumulates in normal, functioning hepatocytes.
价 格:¥电议型 号:T15367产 地:中国大陆
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T15283Firuglipel;化合物 T15283Firuglipel
Firuglipel is an orally available and selective agonist of GPR119.
价 格:¥电议型 号:T15283产 地:中国大陆