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T15273Fedovapagon；非多伐贡VA483|||A106483；VA483|||A106483
Fedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish. Fedovapagon can be used to study overactive bladder, nocturia, and painful bladder syndromes.
价 格：￥电议型 号：T15273产 地：中国大陆
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T15201MAK683；化合物MAK683MAK683
MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).
价 格：￥电议型 号：T15201产 地：中国大陆
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T15183Dynarrestin；化合物DynarrestinDynarrestin
Dynarrestin is a cytoplasmic dynein 1 and 2 aminothiazole inhibitor that reversibly inhibits dynein 1-driven microtubule sliding in vitro and intracellular dynein 1 and 2-dependent processes without affecting ATP hydrolysis and interfering with ciliogenesis .
价 格：￥电议型 号：T15183产 地：中国大陆
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T15136LDiZPK Hydrochloride (1337883-32-5 free base)；化合物 T15136LDiZPK Hydrochloride；DiZPK Hydrochloride
DiZPK Hydrochloride is a structural analog of pyrrolysine (Pyl), acting as a photocrosslinker for identifying direct protein-protein interactions in living prokaryotic and eukaryotic cells.
价 格：￥电议型 号：T15136L产 地：中国大陆
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T15083Dde Biotin-PEG4-alkyne；化合物 T15083Dde Biotin-PEG4-alkyne
Dde Biotin-PEG4-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T15083产 地：中国大陆
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T15015CTS-1027；化合物 T15015RS 130830|||Ro 1130830；RS 130830|||Ro 1130830
CTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has > 1,000 fold selectivity over MMP1.
价 格：￥电议型 号：T15015产 地：中国大陆
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T14977CL-275838；化合物 T14977CL-275838
CL-275838 is a compound of memory-enhancing with potent antidepressant activities.
价 格：￥电议型 号：T14977产 地：中国大陆
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T14942CGP48369；化合物CGP48369CGP48369
CGP48369 is a potent angiotensin II receptor antagonist with antihypertensive effects that enhances endothelium-dependent relaxation of coronary arteries in spontaneously hypertensive rats.
价 格：￥电议型 号：T14942产 地：中国大陆
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T14883Idoxifene；化合物 T14883CB7432；CB7432
Idoxifene is a tissue-specific selective estrogen receptor modulator.
价 格：￥电议型 号：T14883产 地：中国大陆
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T14839Butyrolactone 3化合物 T14839Butyrolactone 3
Butyrolactone 3 is a specifical inhibitor of the histone acetyltransferase Gcn5 (IC50: 100 μM) with a high affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 shows weak inhibitory on CBP (IC50: 0.5 mM).
价 格：￥电议型 号：T14839产 地：中国大陆
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T14838Butoxycarbonyl-PEG5-sulfonic acid；化合物 T14838Butoxycarbonyl-PEG5-sulfonic acid
Butoxycarbonyl-PEG5-sulfonic acid is a PEG-based PROTAC linker utilized for synthesizing PROTACs[1].
价 格：￥电议型 号：T14838产 地：中国大陆
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T14836Bucloxic acid；布氯酸804CB|||Bucloxonic acid|||Esfar；804CB|||Bucloxonic acid|||布氯酸|||Esfar
Bucloxic acid is an anti-inflammatory pyrazole derivative used in the treatment of chronic glomerular nephropathies.
价 格：￥电议型 号：T14836产 地：中国大陆
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T14835BTRX-335140；化合物BTRX-335140CYM-53093；CYM-53093
BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. BTRX-335140 can distribute well into the CNS. ADMET (absorption, distribution, metabolism, excretion, and toxicity) . BTRX-335140 endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats.
价 格：￥电议型 号：T14835产 地：中国大陆
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T14834BT23,6-二氯-2-苯并噻吩羧酸3,6-二氯-2-苯并噻吩羧酸
BT2, a BCKDC kinase (BDK) inhibitor, exhibits an IC50 of 3.19 μM and functions as a potent, selective Mcl-1 inhibitor with a Ki value of 59 μM. Its interaction with BDK induces helix movements in the N-terminal domain, leading to BDK´s dissociation from the branched-chain α-ketoacid dehydrogenase complex (BCKDC).
价 格：￥电议型 号：T14834产 地：中国大陆
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T14833LBS3 Crosslinker disodium双琥珀酰亚胺辛二酸酯钠盐双琥珀酰亚胺辛二酸酯钠盐
BS3 Crosslinker disodium is a non-cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis.
价 格：￥电议型 号：T14833L产 地：中国大陆
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T14833BS3 Crosslinker；化合物 T14833BS3 Crosslinker
BS3 Crosslinker is a non-cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1]. It is utilized specifically for its proficiency in connecting antibodies with drugs, enhancing the overall efficiency and effectiveness of the resulting ADC.
价 格：￥电议型 号：T14833产 地：中国大陆
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T14832BS2G Crosslinker disodium；化合物 T14832BS2G Crosslinker disodium
BS2G Crosslinker (disodium) is a non-cleavable linker employed for synthesizing antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T14832产 地：中国大陆
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T14831Bryostatin 1；苔藓抑素1Bryostatin 1
Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a CNS)permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein (Kis: 8.07 nM and 0.45 nM).
价 格：￥电议型 号：T14831产 地：中国大陆
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T14830Bromperidol溴哌利多溴哌利多|||R-11333
Bromperidol (R-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic. Which is used as an antipsychotic in the treatment of schizophrenia.
价 格：￥电议型 号：T14830产 地：中国大陆
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T1483Citalopram hydrobromide；氢溴酸西酞普兰Lu 10-171|||Nitalapram HBr|||Bonitrile HBr|||XU-62-320|||Lu 10-171 HB
Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system (CNS). Citalopram hydrobromide is the orally bioavailable hydrobromide salt of the racemic bicyclic phthalene derivative citalopram with antidepressant activity. This agent has minimal effects on the CNS neuronal reuptake of norepinephrine (NE) and dopamine (DA).
价 格：￥电议型 号：T1483产 地：中国大陆
