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T13667LDusquetide;化合物 T13667LSGX942;SGX942
Dusquetide is a first-in-class innate defense regulator. Dusquetide displays activity in both reducing inflammation and increasing the clearance of bacterial infection.
价 格:¥电议型 号:T13667L产 地:中国大陆
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T13667Dusquetide TFA (931395-42-5 free base);化合物 T13667SGX942 TFA|||Dusquetide TFA;SGX942 TFA|||Dusquetide
Dusquetide TFA is a kind of innate defense regulator (IDR).Dusquetide TFA has been shown to be active in reducing inflammation and increasing clearance of bacterial infections.Dusquetide TFA regulates innate immune responses to PAMPs and DAMPs in combination with P62.
价 格:¥电议型 号:T13667产 地:中国大陆
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T13666Dupilumab;达必妥REGN-668|||SAR-231893;REGN-668|||SAR-231893
Dupilumab (REGN-668) is a systemic immunomodulator for AD. Dupilumab is a fully human monoclonal antibody against the alpha subunit of the interleukin-4 receptor, which inhibits downstream signaling of IL-4 and IL-13 and has been shown to improve atopic dermatitis.
价 格:¥电议型 号:T13666产 地:中国大陆
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T13665DT2216;化合物DT2216DT2216
DT2216 inhibits various Bcl-XL-dependent leukemias and cancer cells, but is significantly less toxic to platelets.DT2216 is a selective B-cell lymphoma, extremely large (BCL-XL), proteolytic targeting chimera (PROTAC).DT2216 targets bcl-XL to the Von Hippel-Lindau (VHL) E3 ligase for degradation.
价 格:¥电议型 号:T13665产 地:中国大陆
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T13664DSP-4 hydrochloride;化合物DSP-4 hydrochlorideNeurotoxin DSP 4 (hydrochloride);Neurotoxin DSP 4 (hydroch
DSP-4 hydrochloride (Neurotoxin DSP 4 (hydrochloride)) (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC). is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats,
价 格:¥电议型 号:T13664产 地:中国大陆
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T13663Ds-HAPP;化合物 T13663Ds-HAPP
Ds-HAPP is an anthrancenyl and dansyl fluorophore ligand.
价 格:¥电议型 号:T13663产 地:中国大陆
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T13662Diarylalkane derivative 1;化合物 T13662Diarylalkane derivative 1
Diarylalkane derivative 1 is used for the research of pancreatitis.
价 格:¥电议型 号:T13662产 地:中国大陆
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T13661Docosatrienoic Acid;化合物 T13661cis-13,16,19-docosatrienoic acid|||(13Z,16Z,19Z)-13,16,19-Docosatrieno
Docosatrienoic acid is a rare omega-3 fatty acid; Ki value is 5×M, which inhibits the binding of LTB4 to porcine neutrophil membrane.
价 格:¥电议型 号:T13661产 地:中国大陆
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T13663-Pyridylacetic acid hydrochloride;吡啶-3-乙酸盐酸盐3-Pyridylacetic acid hydrochloride
3-Pyridylacetic acid hydrochloride (3-PAA-HCl) is a high homologue of niacin. It is a decomposition product of nicotine (and other tobacco alkaloids). It can also react with amines, alcohols and carboxylic acids, and can also act as an acid in the reaction. catalyst.
价 格:¥电议型 号:T1366产 地:中国大陆
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T13566Bamirastine;巴麦斯汀TAK-427;TAK-427
Bamirastine inhibits ligand binding to recombinant human histamine H1 receptor (rhH1R) with an IC50 value of 17.3 nM.Bamirastine has an inhibitory effect on allergic skin inflammation.
价 格:¥电议型 号:T13566产 地:中国大陆
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T13552ARD-266;化合物 T13552ARD-266
ARD-266 is a highly potent and VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. ARD-266 effectively induces the degradation of AR protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines (DC50s: 0.2-1 nM).
价 格:¥电议型 号:T13552产 地:中国大陆
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T13459(+)-Apogossypol;化合物 T13459Apogossypol|||NSC736630;Apogossypol|||NSC736630
(+)-Apogossypol is an antagonist of pan-BCL-2. (+)-Apogossypol binds to Mcl-1(Bcl-2 and Bcl-xL with EC50s of 2.6, 2.8 and 3.69 μM, respectively).
价 格:¥电议型 号:T13459产 地:中国大陆
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T13398ZINC13466751;化合物ZINC13466751ZINC13466751
ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 ?M).
价 格:¥电议型 号:T13398产 地:中国大陆
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T13385Zamifenacin fumarate;扎非那星富马酸盐UK-76654 fumarate;扎非那星富马酸盐|||UK-76654 fumarate
Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.
价 格:¥电议型 号:T13385产 地:中国大陆
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T13368YLF-466D;化合物YLF-466DC24;C24
YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation.
价 格:¥电议型 号:T13368产 地:中国大陆
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T13366YHO-13351;化合物 T13366YHO-13351
YHO-13351 is the water-soluble prodrug of YHO-13177, which is a potent and specific BCRP inhibitor.
价 格:¥电议型 号:T13366产 地:中国大陆
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T13315VU 6008667化合物 T13315VU 6008667
VU 6008667 is a selective negative allosteric M5 NAM modulator (IC50s: 1.2 μM and 1.6 μM for human M5 and rat M5, respectively).
价 格:¥电议型 号:T13315产 地:中国大陆
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T13285Vatinoxan hydrochloride;化合物 T13285MK-467 hydrochloride|||L-659066 hydrochloride;MK-467 hydrochloride
Vatinoxan hydrochloride is an antagonist of the peripheral α2 adrenergic receptors.
价 格:¥电议型 号:T13285产 地:中国大陆
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T13237LRopsacitinib;化合物RopsacitinibTyk2-IN-8|||PF-06826647;Tyk2-IN-8|||PF-06826647
Ropsacitinib (PF-06826647) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain (IC50: 17 nM).
价 格:¥电议型 号:T13237L产 地:中国大陆