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T11212EPAC 5376753;化合物EPAC 53767535-{[5-(2,4-dichlorophenyl)furan-2-yl]methylidene}-2-thioxodihydropyrimid
EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 ?M in Swiss 3T3 cells.
价 格:¥电议型 号:T11212产 地:中国大陆
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T11122-(Hydroxymethyl)pyridine吡啶甲醇吡啶甲醇|||Piconol
2-(Hydroxymethyl)pyridine (Piconol) is used as an organic synthesis and medicinal chemistry intermediate for the synthesis of the stimulant laxative bisacodyl, and as a pyridinol with hypoglycemic activity.
价 格:¥电议型 号:T1112产 地:中国大陆
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T11086DOTAP chloride;(2,3-二油氧基丙基)三甲基氯化铵1,2-Dioleoyl-3-trimethylammonium-propane chloride;(2,3-二油氧基丙基)三甲基氯化
DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) is a useful and effective cationic lipid transfection DNA(plasmids, BacMIDs) and modified nucleic acids (antisense oligonucleotides) without the use of auxiliary lipids.
价 格:¥电议型 号:T11086产 地:中国大陆
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T11060DMAPT;化合物DMAPTDimethylamino Parthenolide;Dimethylamino Parthenolide
DMAPT (Dimethylamino Parthenolide) is a water-soluble analogue of Parthenolide (PTL). It is an orally active NF-κB inhibitor with an LD50 of 1.7 μM on primary acute myeloid leukemia cells.
价 格:¥电议型 号:T11060产 地:中国大陆
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T11046Dimethyl-SGD-1882;化合物 T11046Dimethyl-PBD dimer;Dimethyl-PBD dimer
Dimethyl-SGD-1882 (Dimethyl-PBD dimer) is a highly efficient DNA alkylating agent used as antibody-drug conjugate (ADC) cytotoxin. PBD Dimer is a DNA alkylating agent that inhibits DNA replication.
价 格:¥电议型 号:T11046产 地:中国大陆
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T11034Di-O-methyldemethoxycurcumin;D-O-甲基脱甲氧基姜黄素Di-O-methyldemethoxycurcumin
Di-O-methyldemethoxycurcumin is a Curcumin analog isolated from medicinal plant turmeric di-orthomethyldemethoxycurcumin, anti-inflammatory and antioxidant properties Inhibition of IL-6 production, EC50 is 16.20μg/mL.
价 格:¥电议型 号:T11034产 地:中国大陆
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T11008Desmethylnortriptyline;化合物 T11008Desmethylnortriptyline
Desmethylnortriptyline is a metabolite of nortriptyline. Nortriptyline is a tricyclic antidepressant. It is the main active metabolite of amitriptyline and is used to relieve depressive symptoms.
价 格:¥电议型 号:T11008产 地:中国大陆
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T11007Desmethyl Levofloxacin;化合物 T11007Desmethyl Levofloxacin
Desmethyl Levofloxacin is a metabolite of levofloxacin. Levofloxacin is a synthetic fluoroquinolone drug, an antibacterial agent that can inhibit the super-coiling activity of bacterial DNA gyrase and prevent DNA replication.
价 格:¥电议型 号:T11007产 地:中国大陆
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T11005Desmethyl Celecoxib;塞来昔布杂质3Desmethyl Celecoxib
Demethyl celecoxib is a selective inhibitor of COX-2 with anti-inflammatory activity (IC50 of 32 nM). with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%.
价 格:¥电议型 号:T11005产 地:中国大陆
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T10990Dehydrocorydaline chloride盐酸脱氢紫堇碱盐酸脱氢紫堇碱|||13-Methylpalmatine chloride
Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.
价 格:¥电议型 号:T10990产 地:中国大陆
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T10980DCPLA-ME;化合物DCPLA-MEMethyl 8-[2-[(2-pentylcyclopropyl)methyl]cyclopropyl]octanoate|||2-[(2-Pentylcyc
DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerative diseases. It is an effective PKCε activator.
价 格:¥电议型 号:T10980产 地:中国大陆
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T10949D8-MMAF;化合物 T10949Monomethylauristatin F D8;Monomethylauristatin F D8
D8-MMAF is a microtubule destroyer, deuterated form of MMAF.
价 格:¥电议型 号:T10949产 地:中国大陆
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T10948MMAE-d8;化合物 T10948D8-MMAE|||D8-Monomethyl auristatin E;D8-MMAE|||D8-Monomethyl auristatin E
D8-MMAE (D8-Monomethyl auristatin E) is an effective mitotic inhibitor and tubulin inhibitor, deuterated MMAE.
价 格:¥电议型 号:T10948产 地:中国大陆
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T10947D8-MMAD;化合物 T10947Monomethylauristatin D D8|||Demethyldolastatin 10 D8|||Monomethyl Dolastatin 10 D8
D8-MMAD is a deuterated form of MMAD, which is a microtubule destroyer.
价 格:¥电议型 号:T10947产 地:中国大陆
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T10886Crocetine dimethyl ester;化合物 Crocetine dimethyl esterDimethylcrocetin;Dimethylcrocetin
Crocetine dimethyl ester (Dimethylcrocetin) is a saffronin derivative with antioxidant activity, inhibition of AChE activity, and inhibition of cell growth and differentiation.
价 格:¥电议型 号:T10886产 地:中国大陆
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T10859COH34;化合物COH341-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol;1-[(E)-(4-methylphenyl)sulf
COH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM. COH34 prolongs PARylation at DNA lesions and traps DNA repair factors.
价 格:¥电议型 号:T10859产 地:中国大陆
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T1083Theophylline;茶碱Theo-24|||1,3-Dimethylxanthine;Theo-24|||1,3-Dimethylxanthine|||茶碱
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3´, 5´-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
价 格:¥电议型 号:T1083产 地:中国大陆
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T1062Capsaicin;辣椒素Qutenza|||8-Methyl-N-vanillyl-trans-6-nonenamide|||Vanilloid|||(E)-Capsaicin|||Zostrix;
Capsaicin ((E)-Capsaicin) is a natural product extracted from Capsicum annuum, and is a TRPV1 agonist (EC50=0.29 μM). Capsaicin has antitumor, anti-inflammatory, antioxidant and neuroprotective activities.
价 格:¥电议型 号:T1062产 地:中国大陆
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T10310Amphotericin B methyl ester;化合物 T10310Amphotericin B methyl ester
Amphotericin B methyl ester is the derivative of the antibiotic Amphotericin B. Amphotericin B methyl ester is the cholesterol-binding compound that possesses significant antifungal activity. It disrupts HIV-1 particle production and potently inhibits HIV-1 replication.
价 格:¥电议型 号:T10310产 地:中国大陆
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T10260Aglafoline;化合物 T10260Rocaglamide U|||Aglafolin|||(-)-Methyl rocaglate;Rocaglamide U|||Aglafolin|||(-
Aglafoline inhibits in a concentration-dependent manner the aggregation and ATP release reaction induced in washed rabbit platelets by PAF (platelet-activating factor). The IC50 values of Aglafoline on PAF (3.6 nM)-induced platelet aggregation were about 50 μM.
价 格:¥电议型 号:T10260产 地:中国大陆