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T21834YM-155 hydrochloride；化合物 T21834YM-155 hydrochloride
Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].
价 格：￥电议型 号：T21834产 地：中国大陆
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T21790BMS 182874 hydrochloride；化合物BMS 182874 hydrochlorideBMS 182874 hydrochloride
BMS 182874 hydrochloride is a nonpeptide endothelin (El) receptor antagonist.
价 格：￥电议型 号：T21790产 地：中国大陆
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T21787LAzepexole hydrochloride；化合物T21787L4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydr
Azepexole hydrochloride (4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydrochloride (1:1)) is a potent α2-Adrenoceptor agonist with anaesthetic effects.
价 格：￥电议型 号：T21787L产 地：中国大陆
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T21787B-HT 933 dihydrochloride；化合物 T21787B-HT 933 dihydrochloride
Azepexole dihydrochloride (B-HT 933), a potent and selective alpha 2-adrenoceptor agonist, exhibits affinity for α2A-, α2B-, and α2C-adrenoceptor subtypes with pKis of 8.3, 7.6, and 7.5, respectively [1]. It elicits a concentration-dependent inhibition of peristaltic contractions, evidenced by an IC50 of 78.72 nM.
价 格：￥电议型 号：T21787产 地：中国大陆
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T21782A 77636 hydrochloride；盐酸A77636A77636 hydrochloride；盐酸A77636|||A77636 hydrochloride
A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM). A 77636 hydrochloride shows antiparkinsonian activity. A 77636 hydrochloride is functionally inactive at dopamine D2 receptor.
价 格：￥电议型 号：T21782产 地：中国大陆
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T2177810-DEBC hydrochloride；化合物 T2177810-DEBC hydrochloride
10-DEBC hydrochloride, a selective Akt inhibitor demonstrating an IC50 value of 1.28 μM, is identified as a novel anti-tuberculosis compound [1] [2].
价 格：￥电议型 号：T21778产 地：中国大陆
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T21772Reserpine hydrochloride化合物 T21772Reserpine hydrochloride|||Reserpine Hydrochloride
Reserpine hydrochloride is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
价 格：￥电议型 号：T21772产 地：中国大陆
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T21768PF-562271 hydrochloride化合物PF-562271 HClPF-562271 HCl
PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
价 格：￥电议型 号：T21768产 地：中国大陆
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T21763Lenalidomide hydrochloride；化合物 T21763Lenalidomide hydrochloride
Lenalidomide hydrochloride (CC-5013 hydrochloride), a Thalidomide derivative, functions as molecular glue and serves as an orally active immunomodulator. As a ligand for the ubiquitin E3 ligase cereblon (CRBN), it facilitates the selective ubiquitination and degradation of the lymphoid transcription factors IKZF1 and IKZF3 through the CRBN-CRL4 ubiquitin ligase. Specifically, Lenalidomide hydrochloride inhibits the growth of mature B-cell lymphomas, including multiple myeloma, and promotes IL-2
价 格：￥电议型 号：T21763产 地：中国大陆
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T21758Calindol (hydrochloride)；化合物 T21758Calindol (hydrochloride)
Calindol (hydrochloride) is a positive allosteric modulator (PAM) of calcimimetic calcium-sensing receptor (CaSR) with an EC50 of 132 nM.
价 格：￥电议型 号：T21758产 地：中国大陆
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T21757BRL 52537 hydrochloride；2-(3,4-二氯苯基)-1-(2-(吡咯烷-1-甲基)哌啶-1-基)乙酮盐酸盐BRL 52537 hydrochloride
BRL 52537 hydrochloride is a selective and specific KOR agonist which has been implicated in neuroprotection from ischemic neuronal injury[1]. It is used for research into potential treatments for stroke and heart attack as well as more general brain research.
价 格：￥电议型 号：T21757产 地：中国大陆
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T217034-Chlorophenylguanidine hydrochloride；洗必泰二乙酸杂质4-Chlorophenylguanidine hydrochloride
4-Chlorophenylguanidine hydrochloride is a potent inhibitor of urokinase selectivity. ?
价 格：￥电议型 号：T21703产 地：中国大陆
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T2170SKF-96365 hydrochloride；化合物SKF-96365 hydrochlorideSKF96365；1-[2-(4-甲氧基)-2-[3-(4-甲氧基苯基)丙氧基]乙基]咪唑|||SK
SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autophagy to delay apoptosis by preventing the release of cytochrome c (cyt c) from the mitochondria into the cytoplasm. Mechanistically, SKF-96365 hydrochloride treatment inhibited the calcium/calmodulin-dependent protein kinase IIγ (CaMKIIγ)/AKT signaling cascade in vitro and in vivo.
价 格：￥电议型 号：T2170产 地：中国大陆
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T21691NVP DPP 728 dihydrochloride；化合物 T21691NVP DPP 728 dihydrochloride
NVP-DPP728 is a potent, reversible, nitrile-dependent inhibitor of dipeptidyl peptidase IV (DPP-IV), demonstrating an inhibition constant (K i) of 11 nM for human DPP-IV amidolytic activity. By inhibiting the degradation of glucagon-like peptide-1 (GLP-1), NVP-DPP728 enhances insulin release following glucose intake, making it useful for diabetes research [1].
价 格：￥电议型 号：T21691产 地：中国大陆
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T21684Bufuralol (hydrochloride)；化合物 T21684Bufuralol (hydrochloride)
Bufuralol hydrochloride (Ro 3-4787 hydrochloride) is a potent non-selective, orally active β-adrenoreceptor antagonist with partial agonist activity, which is also a CYP2D6 probe substrate [1] [2].
价 格：￥电议型 号：T21684产 地：中国大陆
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T21680A 68930 hydrochloride；化合物 T21680A 68930 hydrochloride
A68930 hydrochloride is a dopamine D1 receptor agonist which can be used for the research of bronchiectasis [1].
价 格：￥电议型 号：T21680产 地：中国大陆
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T21677Temafloxacin (hydrochloride)；化合物 T21677Temafloxacin (hydrochloride)
Temafloxacin (hydrochloride) is an antibiotic and antimycobacterial agent. It used to treat lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.
价 格：￥电议型 号：T21677产 地：中国大陆
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T21675SB 203580 hydrochloride；化合物 T21675SB 203580 hydrochloride
Adezmapimod (SB 203580) hydrochloride is a selective ATP-competitive inhibitor of p38 MAPK, displaying IC50 values of 50 nM for SAPK2a/p38 and 500 nM for SAPK2b/p38β2. This compound also inhibits LCK, GSK3β, and PKBα, albeit with IC50 values 100-500 times higher than those for SAPK2a/p38. Additionally, Adezmapimod hydrochloride acts as an activator of autophagy and mitophagy [1].
价 格：￥电议型 号：T21675产 地：中国大陆
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T21669Haloperidol hydrochloride；化合物 T21669Haloperidol hydrochloride
Haloperidol hydrochloride is a potent dopamine D2 receptor antagonist which is a potent antipsychotic agent.
价 格：￥电议型 号：T21669产 地：中国大陆
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T21666Donitriptan hydrochloride；盐酸多尼普曲坦Donitriptan HCl|||Donitriptan monohydrochloride；盐酸多尼普曲坦|||Donitript
Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively
价 格：￥电议型 号：T21666产 地：中国大陆
