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产品数:86101
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T6885MarimastatTA-2516,Marimastat,inhibit,Inhibitor,BB 2516,BB-2516,TA 2516,Matrix metalloproteinases,MMP
Marimastat (BB-2516) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor. MMP-9 (IC50=3 nM), MMP-1 (IC50=5 nM), MMP-2 (IC50=6 nM), MMP-14 (IC50=9 nM)and MMP-7 (IC50=13 nM).
价 格:¥电议型 号:T6885产 地:中国大陆
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T8556Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base)Z Gly Gly Arg AMC TFA (66216 78 2 free base),ZGlyGlyArgA
Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).
价 格:¥电议型 号:T8556产 地:中国大陆
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T9789Cevidoplenib dimesylate hydrochlorideCevidoplenib dimesylate hydrochloride
Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties.
价 格:¥电议型 号:T9789产 地:中国大陆
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T6S1579MonotropeinMonotropein,Inhibitor,inhibit
1. Monotropein has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inflammatory mediators via NF-κB inactivation, and support its possible therapeutic role in colitis. 4. Monotrope ininhibit the expressions of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β) mRNA in LPS-induced RAW 264.7
价 格:¥电议型 号:T6S1579产 地:中国大陆
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T9808Tetradecylthioacetic acidPeroxisome proliferator-activated receptors,β-Oxidation,inhibit,fatty acid
Tetradecylthioacetic acid is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxidation and increases its biological activity, including activation of peroxisome proliferator activated receptors (PPARs) with preference for PPARα.
价 格:¥电议型 号:T9808产 地:中国大陆
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TP1045LOrexin B, rat, mouse AcetateOrexin B, rat, mouse Acetate
Orexin B, rat, mouse Acetate is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.
价 格:¥电议型 号:TP1045L产 地:中国大陆
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T8776FEMA 4774Inhibitor,positive allosteric modulator,sucrose,weetness enhancer,FEMA-4774,T1R3,inhibit,FE
FEMA 4774 is a positive allosteric modulator of T1R2/T1R3. FEMA4774 shows obvious enhancement of the sweetness of sucrose in sensory evaluation tests
价 格:¥电议型 号:T8776产 地:中国大陆
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T40023Pomalidomide-PEG3-CO2H
Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-NH-PEG3-propionic acid incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T40023产 地:中国大陆
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TN1544D-MentholD-Menthol,Microcystis aeruginosa,Inhibitor,Anaesthetic,D Menthol,inhibit,DMenthol
D-Menthol is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes, it attenuates α±7 mediated Ca 2+ transients in the cell body and neurite, suggests that menthol inhibits α±7-nACh receptors in a noncompetitive manner.
价 格:¥电议型 号:TN1544产 地:中国大陆
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T8012Scyllo-InositolScyllo Inositol,Inhibitor,Abeta,ScylloInositol,Scyllo-Inositol,Amyloid-β,β-amyloid pe
Scyllo-Inositol is one of the inositol stereoisomers, rare in the nature, and expected as a promising disease-modifying therapeutic agent for Alzheimer´s disease.
价 格:¥电议型 号:T8012产 地:中国大陆
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T60202MMRi62
MMRi62, a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-independent pro-apoptotic activity against pancreatic ductal adenocarcinoma (PDAC) cells and induce autophagy. MMRi62 inducesferroptosis, resulting in a increase of reactive oxygen and lysosomal degradation of ferritin heavy chain (FTH1). MMRi62 also leads to proteasomal degradation of mutant p53, also inhibits orthotopic xenograft PDAC mouse model in vivo with high frequency mutat
价 格:¥电议型 号:T60202产 地:中国大陆
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T9986(E/Z)-ZINC09659342(E/Z)-ZINC09659342,Inhibitor,Lbc-RhoA interaction,Ras,(E/Z)ZINC09659342,Ras superf
(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.
价 格:¥电议型 号:T9986产 地:中国大陆
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T61972Pomaglumetad methionil hydrochloride
Pomaglumetad methionine hydrochloride (LY2140023 hydrochloride) is a methionine prodrug of LY404039 with oral activity. LY404039 is a selective mGlu2/3 receptor agonist. Pomaglumetad methionil hydrochloride has research value in schizophrenia.
价 格:¥电议型 号:T61972产 地:中国大陆
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T8104Glycyl-L-valineEndogenous Metabolite,GlycylLvaline,Inhibitor,inhibit,Glycyl L valine
Glycyl-L-valine is a dipeptide composed of glycine and valine. It is an incomplete breakdown product of protein digestion or protein catabolism.
价 格:¥电议型 号:T8104产 地:中国大陆
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T9255Zolpidem tartrateZolpidem tartrate
Zolpidem is a prescription medication used for the treatment of insomnia, as well as some brain disorders. It is a short-acting nonbenzodiazepine hypnotic of the imidazopyridine class that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to GABAA receptors at the same location as benzodiazepines.
价 格:¥电议型 号:T9255产 地:中国大陆
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TP1563Gap19myocardial,Gap19,cytoplasmic,Cx40/pannexin-1,inhibit,Gap Junction Protein,C-terminus,Gap 19,hem
Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.
价 格:¥电议型 号:TP1563产 地:中国大陆
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T9826GDC-0214GDC0214,GDC 0214
GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).
价 格:¥电议型 号:T9826产 地:中国大陆
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TN71894,6-Dibromoindole
4,6-Dibromoindole is a marine derived natural products found in Glossobalanus sp.
价 格:¥电议型 号:TN7189产 地:中国大陆
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TN7068Sinomenine N-oxideSinomenine N oxide,Sinomenine Noxide
Sinomenine N-oxide is one of the major metabolites of the cyclic metabolic mechanism of Sinomenine.
价 格:¥电议型 号:TN7068产 地:中国大陆
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T8143Bevantolol hydrochlorideBevantolol hydrochloride,Beta Receptor,Ca2+ channels,cerebral,Inhibitor,inhi
Bevantolol hydrochloride is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.
价 格:¥电议型 号:T8143产 地:中国大陆