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T29140VU0652925;化合物 T29140VU 0652925|||BMS-3|||VU-0652925|||BMS3|||BMS 3;VU 0652925|||BMS-3|||VU-0652925||
VU0652925 is a PAR4 antagonist. VU0652925 has a P-sel IC50 of 39.2 pM (-pIC50±SEM: 10.41±0.04) and a PAC1 IC50 of 43.0 pM (-pIC50±SEM: 10.4±0.04).
价 格:¥电议型 号:T29140产 地:中国大陆
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T28354Peliglitazar;化合物 T28354BMS-426707-1|||BMS 42670701|||BMS 426707-01;BMS-426707-1|||BMS 42670701|||BMS
Peliglitazar is a activator of α/γ peroxisome proliferator-activated receptor.
价 格:¥电议型 号:T28354产 地:中国大陆
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T27616BMS-986094;化合物 T27616INX 08189|||INX-189|||INX189|||INX08189|||INX-08189;INX 08189|||INX-189|||INX18
INX 08189 is an RNA-directed RNA polymerase (NS5B) inhibitor.
价 格:¥电议型 号:T27616产 地:中国大陆
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T27588Ifetroban;伊非曲班BMS180291|||BMS-180291|||BMS 180291-02;伊非曲班|||BMS180291|||BMS-180291|||BMS 180291-02
Ifetroban is a potent and selective TxA2/PGH2 receptor antagonist.
价 格:¥电议型 号:T27588产 地:中国大陆
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T27410Gemopatrilat;化合物 T27410BMS189921|||BMS-189921|||BMS 189921;BMS189921|||BMS-189921|||BMS 189921
Gemopatrilat is a an vasopeptidase inhibitor.
价 格:¥电议型 号:T27410产 地:中国大陆
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T2699BMS 777607;化合物BMS-777607BMS777607|||BMS-777607|||BMS 817378;BMS777607|||BMS-777607|||BMS 817378
BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3 (IC50: 3.9/1.1/1.8/4.3 nM). BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.
价 格:¥电议型 号:T2699产 地:中国大陆
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T26870BMS-986124;化合物 T26870BMS 986124|||BMS-986122;BMS 986124|||BMS-986122
BMS-986124 is an allosteric modulator of the μ-Opioid Receptor.
价 格:¥电议型 号:T26870产 地:中国大陆
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T26869BMS-986122;化合物BMS-986122BMS 986122;BMS 986122
BMS-986122 (BMS 986122) is a positive allosteric modulator of μ-opioid receptors that increases β-arrestin recruitment stimulated by endomorphin 1 in U2OS-OPRM1 human osteosarcoma cells expressing μ-opioid receptors (EC50 = 3 μM).
价 格:¥电议型 号:T26869产 地:中国大陆
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T26868BMS-986118;化合物 T26868BMS 986118;BMS 986118
BMS-986118 is a full agonist of GPR40, is a G-protein-coupled receptor expressed primarily in pancreatic islets and intestinal L-cells that has been a target of significant recent therapeutic interest for type II diabetes. Activation of GPR40 by partial agonists elicits insulin secretion only in the presence of elevated blood glucose levels, minimizing the risk of hypoglycemia.
价 格:¥电议型 号:T26868产 地:中国大陆
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T26867BMS-986104 HCl;化合物 T26867BMS986104|||BMS-986104|||BMS 986104;BMS986104|||BMS-986104|||BMS 986104
BMS-986104 is a potent and selective S1P1 receptor modulator.
价 格:¥电议型 号:T26867产 地:中国大陆
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T26866BMS-960;化合物BMS-960BMS 960|||BMS960;BMS 960|||BMS960
BMS-960 is an S1P agonist with potential anti-tumour activity for cancer research.
价 格:¥电议型 号:T26866产 地:中国大陆
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T26865BMS-933043;化合物 T26865BMS933043;BMS933043
BMS-933043 is a Selective α7 nAChR partial agonist. BMS-933043 showed potent binding affinity to native rat (Ki = 3.3 nM) and recombinant human alpha7 nicotinic acetylcholine receptors (Ki = 8.1 nM). BMS-933043 shows agonist activity in a calcium fluorescence assay (EC50 = 23.4 nM) and whole cell voltage clamp electrophysiology (EC50 = 0.14 μM (rat) and 0.29 μM (human)).
价 格:¥电议型 号:T26865产 地:中国大陆
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T26864BMS-932481;化合物 T26864BMS932481;BMS932481
BMS-932481 is a γ-secretase modulator.
价 格:¥电议型 号:T26864产 地:中国大陆
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T26863BMS-929075;化合物BMS-929075BMS 929075|||BMS929075;BMS 929075|||BMS929075
BMS-929075 is an orally active HCV NS5B replicase (HCV NS5B replicase) palm site variant inhibitor with potency, high oral bioavailability and pharmacokinetic parameters.BMS-929075 shows cytotoxicity.
价 格:¥电议型 号:T26863产 地:中国大陆
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T26862BMS-902483;化合物 T26862BMS-902483
BMS-902483 is a potent α7 partial agonist. BMS-902483 improved cognition in preclinical rodent models. BMS-902483 showed FLIR α7 EC50=9.3nM; α7 Electrophysiology, rat; Area EC50 = 140 nM; Peak, Area (Ymax %) = 40, 54. 5-HT3A IC50 = 480 nm.
价 格:¥电议型 号:T26862产 地:中国大陆
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T26861BMS-817399;化合物BMS-817399BMS817399;BMS817399
BMS-817399 is an orally active antagonist of CCR1 with IC50s of binding affinity and chemotaxis inhibition potencies and can be used in studies about rheumatoid arthritis.
价 格:¥电议型 号:T26861产 地:中国大陆
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T26860BMS-814580;化合物 T26860BMS-814580
BMS-814580 is a potent and selective functional antagonist (Kb = 117 nM) of human MCHR1. BMS-814580 exhibits potent binding affinity (Ki = 17 nM) for human MCHR1. BMS-814580 also exhibits potent binding affinities for cynomolgus monkey and rat MCHR1 (Ki of 4.9 and 11.5 nM, respectively). MCHR1 antagonist demonstrates reduction in feeding and body weight in rats and mice.
价 格:¥电议型 号:T26860产 地:中国大陆
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T26859BMS-8;化合物BMS-8BMS-8
BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.
价 格:¥电议型 号:T26859产 地:中国大陆
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T26858BMS-770767;化合物 T26858BMS-770767
BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11?-HSD1) inhibitor.
价 格:¥电议型 号:T26858产 地:中国大陆
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T26857BMS-767778;化合物 T26857BMS-767778
BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.
价 格:¥电议型 号:T26857产 地:中国大陆