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T6726VU0361737Parkinson’s,inhibit,ML128,neuroprotective,Metabotropic glutamate receptors,VU0361737,Inhibi
VU 0361737 is a specific positive allosteric modulator (PAM) of mGlu4 receptor.The EC50 of VU 0361737 is 240 nM for the human receptors. The EC50 of VU 0361737 is110 nM for rat receptors.It exhibits weak activity at mGlu5 and mGlu8 receptors, and is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.
价 格:¥电议型 号:T6726产 地:中国大陆
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T6389Anacardic AcidBacterial,HATs,inhibit,HAT,Anacardic Acid,Histone Acetyltransferase,Ginkgolic Acid C15
Anacardic Acid is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial activity, antibacterial activity, and inhibits prostaglandin synthase, lipoxygenase, and tyrosinase.
价 格:¥电议型 号:T6389产 地:中国大陆
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T6878LJI308viability,Ribosomal S6 Kinase (RSK),LJI-308,stimulation,phosphorylation,LJI308,inhibit,mutatio
LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.
价 格:¥电议型 号:T6878产 地:中国大陆
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TN6791Palvanilanti-inflammation,inhibit,HEK-293,Inhibitor,anti-nociceptive,Palvanil
Palvanil is a fast desensitizing agonist of TRPV1. it may be promising agents in the therapy of IBS since it modulates intestinal motility and reduces visceral pain.
价 格:¥电议型 号:TN6791产 地:中国大陆
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T7412Tandospirone citrateSM3997,SM-3997,Tandospirone,Tandospirone citrate,Inhibitor,Serotonin Receptor,SM
Tandospirone citrate is a potent and selective 5-HT1A receptor partial agonist (Ki : 27 nM)
价 格:¥电议型 号:T7412产 地:中国大陆
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T9382Thalidomide-NH-C2-PEG3-OHinhibit,Inhibitor,Thalidomide-NH-C-2-PEG3-OH,E3 Ligase Ligand-Linker Conjug
Thalidomide-NH-C2-PEG3-OH is an E3 ligase ligand-linker conjugate.
价 格:¥电议型 号:T9382产 地:中国大陆
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T6919OmaveloxoloneInhibitor,Omaveloxolone,Apoptosis,RTA 408,RTA408,ERIS,STING,inhibit,Stimulator of Inter
Omaveloxolone (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.
价 格:¥电议型 号:T6919产 地:中国大陆
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T6481DroxinostatHDAC3,hepatocellular carcinoma (HCC),Droxinostat,NS-41080,Apoptosis,Histone deacetylases,
Droxinostat is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
价 格:¥电议型 号:T6481产 地:中国大陆
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T8349Cyclofenilmaturation,inhibit,Cyclofenil,Zika,FSH,Estrogen Receptor/ERR,Influenza Virus,replication,I
Cyclofenil is an estrogen antagonist, has anti-dengue-virus activity
价 格:¥电议型 号:T8349产 地:中国大陆
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T5043Lentinanresponse,β-glucan,Shiitake,gastric,inhibit,cancer,Lentinan,modifier,Inhibitor,biological,mus
Lentinan, isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.
价 格:¥电议型 号:T5043产 地:中国大陆
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T21996Zoniporide hydrochloride
Zoniporide hydrochloride is a selective inhibitor of NHE-1 with IC50 of 14 nM which is >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride shows an IC50 of 59 nM for NHE-1-dependent swelling of human platelets.
价 格:¥电议型 号:T21996产 地:中国大陆
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T9461AZ194nociceptive neurotransmission,Inhibitor,CRMP2-Ubc9 interaction,Na+ channels,Na channels,inhibit
CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
价 格:¥电议型 号:T9461产 地:中国大陆
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T98967-Methoxy-1-naphthylacetonitrile7Methoxy1naphthylacetonitrile,7 Methoxy 1 naphthylacetonitrile
7-Methoxy-1-naphthylacetonitrile is one of the impurities of agomelatine, an antidepressant.
价 格:¥电议型 号:T9896产 地:中国大陆
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TN1524Continentalic acidContinentalic acid,Bacterial,inhibit,Inhibitor
Continentalic acid from Aralia continentalis has minimum inhibitory concentrations (MICs) of approximately 8-16 ?g/mL against S. aureus, including the Methicillin-resistant Staphylococcus aureus (MRSA) and Methicillin susceptible Staphylococcus aureus (MSSA) and standard strains.
价 格:¥电议型 号:TN1524产 地:中国大陆
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TN7168Farnesylacetone
(5E,9E)-6,10,14-Trimethylpentadeca-5,9,13-trien-2-one is a marine derived natural products found in Sargassum micracanthum.
价 格:¥电议型 号:TN7168产 地:中国大陆
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TN1693GlabronePPAR,Peroxisome proliferator-activated receptors,Glabrone,inhibit,Inhibitor
Glabrone shows antiviral activity against influenza virus.
价 格:¥电议型 号:TN1693产 地:中国大陆
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T23445Anxiolytic/nonsedative agent-1
Anxiolytic/nonsedative agent-1 is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo.
价 格:¥电议型 号:T23445产 地:中国大陆
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T38287C3a Receptor Agonist
C3a Receptor Agonist binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR prevents neutrophils from being mobilized in a model of intestinal ischemia-reperfusion injury. C3aRs are expressed on neural progenitor cells and immature neurons in adult mice. C3a stimulates differentiation of neural progenitor cells in vitro.
价 格:¥电议型 号:T38287产 地:中国大陆
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TN71324,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone4,12Dimethoxy6(7,8dihydroxy7,8dihydrostyr
4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone is a microbial metabolism of yangonin, a major styryl lactone from Piper methysticum.
价 格:¥电议型 号:TN7132产 地:中国大陆
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T6833FavipiravirSARS-CoV,DNA/RNA Synthesis,Influenza Virus,T705,inhibit,SARS coronavirus,Favipiravir,Inhi
Favipiravir (T-705), an effective and selective RNA-dependent RNA polymerase inhibitor, are applied to treat influenza virus infections.
价 格:¥电议型 号:T6833产 地:中国大陆