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TQ0046BavisantJNJ31001074,JNJ 31001074,Neurological disorders,inhibit,Histamine Receptor,attention-deficit
Bavisant is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD.
价 格：￥电议型 号：TQ0046产 地：中国大陆
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T9521CHR-6494 TFACHR-6494,inhibit,apoptosis,Haspin Kinase,NRAS mutant melanoma cells,CHR 6494,mitotic cat
CHR-6494 TFA is a potent haspin inhibitor, with an?IC50?of 2 nM. It inhibits histone H3T3 phosphorylation. CHR-6494 TFA induces the?apoptosis?of cancer cells, including melanoma and breast cancer. CHR-6494 TFA can be used in the research of cancer
价 格：￥电议型 号：T9521产 地：中国大陆
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T6S0052ChelerythrineBcl-2 Family,Apoptosis,Protein kinase C,PKC,Inhibitor,Chelerythrine,inhibit,Autophagy
1. Chelerythrine may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiproliferative and antitumor effects.
价 格：￥电议型 号：T6S0052产 地：中国大陆
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T6312R547Glycogen synthase kinase 3,kinase,multiple,tumor,cyclin-dependent,R547,Apoptosis,Cyclin dependen
R547 is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.
价 格：￥电议型 号：T6312产 地：中国大陆
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T9172Simufilam dihydrochlorideInhibitor,PTI-125,Simufilam,inhibit,PTI 125,PTI125,Simufilam dihydrochlorid
Simufilam dihydrochloride is a low toxicity, orally active filamin A (FLNA) activator, which can be used for the research of Alzheimer´s disease. Simufilam dihydrochloride preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.
价 格：￥电议型 号：T9172产 地：中国大陆
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T6527GW842166XGW842166X,inhibit,Cannabinoid Receptor,GW-842166X,Inhibitor
GW842166X is a potent and highly selective agonist of cannabinoid receptor CB2 receptor with EC50 of 63 nM, shows no significant activity at CB1 receptor. Phase 2.
价 格：￥电议型 号：T6527产 地：中国大陆
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T7370TalarozoleRetinoid X receptors,R 115866,Retinoic acid receptors,RAR/RXR,inhibit,Talarozole,Cytochrom
Talarozole is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively.Talarozole for the treatment of acne, psoriasis and other keratinization disorders.
价 格：￥电议型 号：T7370产 地：中国大陆
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T8788NaptalamInhibitor,Alanap-1,transport inhibitor,inhibit,Alanap 1,Alanap1,maize,polar auxin,leaf margi
Naptalam is an herbicide.Naptalam is a dicarboxylic acid monoamide which results from addition of one equivalent of 1-naphthylamine to phthalic anhydride. It is a dicarboxylic acid monoamide, a carboxylic acid and a N-(1-naphthyl)carboxamide. It is a conjugate acid of a naptalamate.
价 格：￥电议型 号：T8788产 地：中国大陆
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TP1065PAR-4 Agonist Peptide, amide TFAThrombin receptors,PAR4 Agonist Peptide, amide TFA,Protease Activate
PAR-4 Agonist Peptide, amide TFA is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.
价 格：￥电议型 号：TP1065产 地：中国大陆
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T22667CID 5951923Krüppel-like factor,CID-5951923,CID5951923,KLF5,inhibit,cancer,factor,KLF,transcription,I
CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.
价 格：￥电议型 号：T22667产 地：中国大陆
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T6S2315Polyphyllin VIPolyphyllin VI,inhibit,Pyroptosis,Apoptosis,Inhibitor
1. Polyphyllin VI has hemostasis , expectorant , bacteriostasis, anticytotoxic, anti pregnancy kill sperm effects.
价 格：￥电议型 号：T6S2315产 地：中国大陆
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T8221Insulin (human)Insulin Receptor,Inhibitor,Insulin (human),inhibit
INSULIN is a polypeptide hormone that regulates the level of glucose.
价 格：￥电议型 号：T8221产 地：中国大陆
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TP1327LOVA Peptide 257-264 2TFA (138831-86-4 free base)OVA Peptide 257264 2TFA (138831864 free base),OVA Pe
OVA Peptide 257-264 2TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
价 格：￥电议型 号：TP1327L产 地：中国大陆
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T7414ARS-853ARS 853,ARS-853,KRAS,Apoptosis,cancer,mutant,state,inhibit,Inhibitor,inactive,Ras,selective,c
ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells
价 格：￥电议型 号：T7414产 地：中国大陆
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T7045ClonidineClonidine,α2-adrenergic,inhibit,Inhibitor,anesthesia,Adrenergic Receptor,Beta Receptor
Clonidine is a centrally active alpha-adrenergic agonist used predominantly as an antihypertensive agent, usually in combination with other agents. Despite wide-scale use for many years, clonidine has not been linked definitively to either serum aminotransferase elevations or clinically apparent liver injury.
价 格：￥电议型 号：T7045产 地：中国大陆
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T8901YUM70Heat shock proteins,YUM70,HSP,cancer,pancreatic,reticulum,Apoptosis,GRP78,YUM-70,stress-mediate
YUM70 is a potent and selective glucose-regulated protein 78 (GRP78) inhibitor(with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein). It induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.
价 格：￥电议型 号：T8901产 地：中国大陆
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T7555Piperidolate hydrochlorideInhibitor,Piperidolate,inhibit,Muscarinic acetylcholine receptor,Piperidol
Piperidolate hydrochloride is an antimuscarinic, could restrain the abnormal activity caused by acetylcholine. inhibits intestinal cramp induced by acetylcholine (rats and dogs).
价 格：￥电议型 号：T7555产 地：中国大陆
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T9912TrastuzumabEGFR,Trastuzumab,Anti-Human HER2, Humanized Antibody,Epidermal growth factor receptor,HER
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer.
价 格：￥电议型 号：T9912产 地：中国大陆
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T21747VU0483605Inhibitor,inhibit,VU0483605,Metabotropic glutamate receptors,allosteric modulator,brain pen
VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.
价 格：￥电议型 号：T21747产 地：中国大陆
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T7001TIC10TIC 10,Tumor Necrosis Factor Receptor,inhibit,ONC201,Inhibitor,TNF Receptor,Apoptosis,TNFR,ONC
TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
价 格：￥电议型 号：T7001产 地：中国大陆
