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T11023DHODH-IN-14DHODH IN 14,DHODHIN14
DHODH-IN-14 is an analog of hydroxyfuran pyrimidine A771726. DHODH-IN-14 is a dihydroorotate dehydrogenase (DHODH) inhibitor IC50 0.49 μM mouse liver DHODH. DHODH-IN-14 can be used for rheumatoid arthritis.
价 格:¥电议型 号:T11023产 地:中国大陆
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T61392NLRP3-IN-10
NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading to suppress activation of NLRP3 inflammasome.
价 格:¥电议型 号:T61392产 地:中国大陆
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T60146USP8-IN-1USP8inhibitor
USP8-IN-1 is an inhibitor of USP8 with an IC 50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI 50 of 82.04 μM [1].
价 格:¥电议型 号:T60146产 地:中国大陆
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T7356PTP1B-IN-1Inhibitor,PTP-1B-IN-1,PTP1BIN1,inhibit,Phosphatase,PTP1B IN 1
PTP1B-IN-1 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)
价 格:¥电议型 号:T7356产 地:中国大陆
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T8418DCLK1-IN-1DCLK1 IN 1,signaling,PDAC,KRAS,cancer,low,ERK,Inhibitor,selective,DCLK1IN1,inhibit,DCLK-1-
DCLK1-IN-1 is a selective and in vivo-compatible chemical probe of the DCLK1 kinase domain .
价 格:¥电议型 号:T8418产 地:中国大陆
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T12902SHMT-IN-1SHMT IN 1,SHMTIN1
SHMT-IN-1 is a potent plasmodial serine hydroxymethyltransferase (SHMT) inhibitor with antitumor activity.
价 格:¥电议型 号:T12902产 地:中国大陆
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T19206β-Lactamase-IN-1
β-Lactamase-IN-1 is a β-Lactamase inhibitor and targets the infection of Neisseria gonorrhoeae.
价 格:¥电议型 号:T19206产 地:中国大陆
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T10643c-Fms-IN-1cFmsIN1,c Fms IN 1
c-Fms-IN-1 is an inhibitor of c-FMS kinase (IC50 = 0.8 nM).
价 格:¥电议型 号:T10643产 地:中国大陆
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T8323LolCDE-IN-1antibacterial,inhibit,Bacterial,LolCDEIN1,Inhibitor,LolCDE IN 1,LolCDE
LolCDE-IN-1 is an inhibitor of the Lol proteins (LolCDE) complex. LolCDE-IN-1 shows antibacterial activity.
价 格:¥电议型 号:T8323产 地:中国大陆
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T7015Vps34-IN-1inhibit,Autophagy,Vps34IN1,PI3K,Vps-34-IN-1,Inhibitor,Phosphoinositide 3-kinase,Vps34 IN 1
Vps34-IN1 is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM invitro, which does not significantly inhibit the isoforms of class I as well as class II PI3Ks.
价 格:¥电议型 号:T7015产 地:中国大陆
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T10623BSH-IN-1BSH IN 1,BSHIN1
BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM and 427 nM for B. longum BSH and B. theta BSH).
价 格:¥电议型 号:T10623产 地:中国大陆
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T8659K-Ras-PDEδ-IN-1KRasPDEδIN1,PDEδ,cancer,pyrazolopyridazinone-based,inhibit,K Ras PDEδ IN 1,Inhibitor,
K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM).
价 格:¥电议型 号:T8659产 地:中国大陆
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T61969AChE/BChE-IN-10
AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation.
价 格:¥电议型 号:T61969产 地:中国大陆
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T10201PDE IV-IN-1PDE IVIN1,PDE IV IN 1
PDE IV-IN-1 is a phosphodiesterase IV inhibitor used for the research of COPD, asthma, or other inflammatory diseases.
价 格:¥电议型 号:T10201产 地:中国大陆
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T9742SETDB1-TTD-IN-1SETDB1TTDIN1,SETDB1 TTD IN 1,SETDB-1-TTD-IN-1
SETDB1-TTD-IN-1 is a potent, selective and endogenous binder competitive inhibitor of SETDB1-TTD with a Kd of 88 nM.
价 格:¥电议型 号:T9742产 地:中国大陆
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T9053Lats-IN-1inhibit,LatsIN1,YAP,Yes-associated protein,Lats IN 1,Inhibitor
Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.
价 格:¥电议型 号:T9053产 地:中国大陆
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T9627PHD-1-IN-1pocket,ion,Arg367-out,HIF-PH,Hypoxia-inducible factors,site,active,PHD 1 IN 1,orally,Inhib
PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).
价 格:¥电议型 号:T9627产 地:中国大陆
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T1016011β-HSD1-IN-111β-HSD-1-IN-1,11βHSD1IN1,11β HSD1 IN 1
11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.
价 格:¥电议型 号:T10160产 地:中国大陆
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T40146Sec61-IN-1Sec61IN1,Sec61 IN 1,Sec-61-IN-1
Sec61-IN-1 is a potent sec61 inhibitor (Patent WO2020176863A1, compound A317).
价 格:¥电议型 号:T40146产 地:中国大陆
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T10863Complement C5-IN-1Complement C-5-IN-1,Complement C5 IN 1,Complement C5IN1
Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).
价 格:¥电议型 号:T10863产 地:中国大陆