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T9041AES-350Histone deacetylases,AES 350,MV4-11,AES-350,Apoptosis,acute myeloid leukemia,AML,Inhibitor,in
AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.
价 格:¥电议型 号:T9041产 地:中国大陆
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T6908NSC 228155Epidermal growth factor receptor,Histone Acetyltransferase,EGFR,HER1,HATs,inhibit,Inhibito
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
价 格:¥电议型 号:T6908产 地:中国大陆
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T60072ZL0590non-KAc binding site,ZL0590,ZL-0590,BRD4 BD1,Inhibitor,acute airway inflammation,inhibit,Epige
ZL0590 is an effective and selective inhibitor of BD1-BRD4 (IC50 = 90 nM) with anti-inflammatory activities.
价 格:¥电议型 号:T60072产 地:中国大陆
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T6990LSNAP8 Acetate(868844-74-0,free base)SNAP8 Acetate(868844 74 0,free base),SNAP8 Acetate(868844740,fre
Diminishing the appearance of wrinkles.
价 格:¥电议型 号:T6990L产 地:中国大陆
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T22900L-701252
L-701252 is a potent antagonist of glycine site NMDA receptor with an IC50 of 420 nM. L-701252 provides a small degree of neuroprotection in global cerebral ischaemia.
价 格:¥电议型 号:T22900产 地:中国大陆
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T24905TT01001
TT01001 is a selective agonist of mitoNEET and reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 can be used in studies about the treatment of type II diabetes.
价 格:¥电议型 号:T24905产 地:中国大陆
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TN6901Methyl myristateB16F10,Methyl myristate,melanin,myristic acid,inhibit,Inhibitor
Methyl myristate is a natural product.
价 格:¥电议型 号:TN6901产 地:中国大陆
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T8990ML266ML266
ML266 is glucocerebrosidase (GCase) molecule chaperone, IC50 = 2.5 ?M. ML266 binds to GCase and transports of the mutant protein to the lysosome, and resume the activity of GCase. ML266 dose not inhibit the GCase enzyme’s action. ML266 has the potential for the research of gaucher disease.
价 格:¥电议型 号:T8990产 地:中国大陆
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T90597Compound 1549Compound 1549
SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 ( IC 50 =18, 15, and 38 nM, respectively). SSR504734 exhibits activity in schizophrenia, anxiety and depression models [1].
价 格:¥电议型 号:T90597产 地:中国大陆
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T9059Fmoc-Phe(4-CN)-OHFmoc Phe(4 CN) OH,Inhibitor,FmocPhe(4CN)OH,inhibit
Fmoc-Phe(4-CN)-OH?is an N-Fmoc protected phenylalanine derivative and potentially useful synthetic intermediate
价 格:¥电议型 号:T9059产 地:中国大陆
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T9040Aurora kinase inhibitor-2inhibit,Aurora-A,Aurora kinase inhibitor2,Aurora Kinase,ATP-competitive,Aur
Aurora Kinase Inhibitor II is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).
价 格:¥电议型 号:T9040产 地:中国大陆
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T9031MCU-i4C2C12,Inhibitor,mitochondrial,MCU-i-4,Mitochondrial Metabolism,MCU-i4,MCUi4,Ca2+,uptake,inhibi
MCU-i4 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.
价 格:¥电议型 号:T9031产 地:中国大陆
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T12902SHMT-IN-1SHMT IN 1,SHMTIN1
SHMT-IN-1 is a potent plasmodial serine hydroxymethyltransferase (SHMT) inhibitor with antitumor activity.
价 格:¥电议型 号:T12902产 地:中国大陆
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T7132(Rac)-BrassinazoleCytochrome P450,brassinosteroid,(Rac)Brassinazole,triazole-type,CYP90B,CYPs,biosyn
Brassinosteroids are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole is a triazole-type brassinosteroid biosynthesis inhibitor.
价 格:¥电议型 号:T7132产 地:中国大陆
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Fr13901Compound Fr13901Compound Fr13901
价 格:¥电议型 号:Fr13901产 地:中国大陆
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T9084Cetirizine Impurity B dihydrochlorideinhibit,Cetirizine Impurity B,Inhibitor,Cetirizine Impurity B d
Cetirizine Impurity B dihydrochloride is an impurity of Cetirizine dihydrochloride. Cetirizine is a second-generation antihistamine. Cetirizine is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
价 格:¥电议型 号:T9084产 地:中国大陆
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T6118NVP-HSP990HSP-990,NVP-HSP990,Apoptosis,Heat shock proteins,NVP HSP990,HSP,NVP-HSP-990,HSP 990,Inhibi
NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).
价 格:¥电议型 号:T6118产 地:中国大陆
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T9098DMG-PEG 2000Inhibitor,therapy,T2D,lPEI/DNA nanoparticle,type II diabete,A549,HepG2,inhibit,HeLa,DMG-
DMG-PEG2000 is a lipid excipient that has been used in combination with other lipids in the formation of lipid nanoparticles. Formulations containing DMG-PEG2000 have been used in the development of lipid nanoparticles for the delivery of mRNA-based vaccines.
价 格:¥电议型 号:T9098产 地:中国大陆
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T7430AM-0902Transient receptor potential channels,TRP Channel,AM 0902,AM-0902,Inhibitor,inhibit,AM0902
AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).
价 格:¥电议型 号:T7430产 地:中国大陆
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T8435YM90Kanticonvulsant,AMPA,Inhibitor,ischemia,inhibit,neuroprotective,Ionotropic glutamate receptors,Y
YM90K hydrochloride is an antagonist of AMPA receptor.
价 格:¥电议型 号:T8435产 地:中国大陆