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T14303Alrizomadlin
Alrizomadlin is an orally active inhibitor of MDM2 with IC50 of 3.8 nM and Ki of 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner.
价 格:¥电议型 号:T14303产 地:中国大陆
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TQ0127NavtemadlinNavtemadlin,MDM-2/p53,inhibit,Ubiquitin ligase,Ubiquitin activating enzyme,E3 ligating en
AMG 232 is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM). It binds to MDM2 with a Kd of 0.045 nM.
价 格:¥电议型 号:TQ0127产 地:中国大陆
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T14551BevenopranInhibitor,CB 5945,Bevenopran,CB5945,inhibit,Opioid Receptor,ADL 5945,ADL5945
Bevenopran is a peripheral antagonist of μ-opioid receptor and can be used in studies about the treatment of opioid-induced bowel dysfunction.
价 格:¥电议型 号:T14551产 地:中国大陆
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T6175ADL-5859ADL5859 HCl;ADL5859 Hydrochloride
ADL5859 HCl is a selective δ-opioid receptor agonist ( Ki: 0.8 nM), selectivity against opioid receptor κ, μ, and little inhibition for the hERG channel.
价 格:¥电议型 号:T6175产 地:中国大陆
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T5555SiremadlinNVP-HDM 201
Siremadlin is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor.
价 格:¥电议型 号:T5555产 地:中国大陆
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T1242Alvimopan爱维莫潘;ADL 8-2698;LY 246736
Alvimopan is a synthetic trans-3, 4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid receptors, found in myenteric and submucosal n
价 格:¥电议型 号:T1242产 地:中国大陆
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T0209Loperamide hydrochloride盐酸洛哌丁胺;ADL 2-1294;Loperamide HCl;R-18553 (hydrochloride)
Loperamide Hydrochloride is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.
价 格:¥电议型 号:T0209产 地:中国大陆
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T11055DL-TBOADL-TBOA
DL-TBOA inhibited [14C] glutamate uptake in COS-1 cells expressing human EAAT1 and EAAT2, with Ki values of 42 μM and 5.7 μM, respectively. DL-TBOA blocks EAAT4 and EAAT5 in a competitive manner, with Ki values of 4.4 μM and 3.2 μM, respectively. DL-TBOA
价 格:¥电议型 号:T11055产 地:美洲
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T12274Siremadlin R EnantiomerSiremadlin R Enantiomer,NVP-HDM201 R Enantiomer,HDM201 R Enantiomer
Siremadlin R Enantiomer is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific inhibitor of MDM-2/p53.
价 格:¥电议型 号:T12274产 地:美洲
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T1242AlvimopanAlvimopan,LY 246736,ADL 8-2698
Alvimopan is a synthetic trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid receptors, found in myenteric and submucosal ne
价 格:¥电议型 号:T1242产 地:美洲
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T15140DLinDMADLinDMA
DLinDMA, as a benchmark, is a key stable nucleic acid lipid particleslipid component.
价 格:¥电议型 号:T15140产 地:美洲
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T6175ADL5859 HClADL5859 HCl,ADL-5859,ADL5859 Hydrochloride
ADL5859 HCl is a selective δ-opioid receptor agonist ( Ki: 0.8 nM), selectivity against opioid receptor κ, μ, and little inhibition for the hERG channel.
价 格:¥电议型 号:T6175产 地:美洲
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T83656DLIN-MC4-DMA;化合物 DLIN-MC4-DMADLIN-MC4-DMA
DLIN-MC4-DMA is a lipid membrane and is a potential nucleic acid carrier.
价 格:¥电议型 号:T83656产 地:中国大陆
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T83655DLIN-MC2-DMA;化合物 DLIN-MC2-DMADLin-M-C2-DMA;DLin-M-C2-DMA
DLIN-MC2-DMA (DLin-M-C2-DMA) is a lipid membrane and a potential nucleic acid carrier.
价 格:¥电议型 号:T83655产 地:中国大陆
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T79854Lingdolinurad;化合物 LingdolinuradLingdolinurad
Lingdolinurad is a uric acid transporter protein inhibitor targeting hURAT1 for the study of hyperuricemia or gout.
价 格:¥电议型 号:T79854产 地:中国大陆
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T76569Sulanemadlin;化合物 SulanemadlinSulanemadlin
Sulanemadlin (ALRN-6924) is a potent peptidomimetic macrocycle that serves as an inhibitor of the p53-MDM2 and p53-MDMX protein-protein interactions. It is capable of inhibiting either or both of these interactions, positioning it as a valuable tool for cancer research [1].
价 格:¥电议型 号:T76569产 地:中国大陆
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T74379DLin-K-C3-DMA;化合物 DLin-K-C3-DMADLin-K-C3-DMA
DLin-K-C3-DMA, a cationic lipid, facilitates the synthesis of nucleic acid-lipid particles for nucleic acid delivery [1].
价 格:¥电议型 号:T74379产 地:中国大陆
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T70267ADL 08-0011 HCl;化合物 ADL 08-0011 HClADL 08-0011 HCl
ADL 08-0011 is an active metabolite of the μ-opioid receptor antagonist alvimopan. It is produced from alvimopan via amide hydrolysis by gut microbiota. ADL 08-0011 is a μ-opioid receptor antagonist (Ki = 0.25 nM). It is selective for μ-opioid receptors over κ- and δ-opioid receptors (Kis = 15.8 and 31.6 nM, respectively). ADL 08-0011 inhibits endomorphin 1-induced inhibition of electrically induced contraction of isolated guinea pig ileum (pA2 = 9.4). In vivo, ADL 08-0011 (0.03-1 mg/kg) reverse
价 格:¥电议型 号:T70267产 地:中国大陆
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T69923Brigimadlin;化合物 BrigimadlinBI 907828;BI 907828
Brigimadlin (BI 907828), an E3 ubiquitin-protein ligase MDM-2 inhibitor, functions as an antineoplastic agent.
价 格:¥电议型 号:T69923产 地:中国大陆
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T6175ADL-5859;化合物ADL5859 HClADL5859 Hydrochloride|||ADL5859 HCl;ADL5859 Hydrochloride|||ADL5859 HCl
ADL-5859 (ADL5859 Hydrochloride) is a selective δ-opioid receptor agonist ( Ki: 0.8 nM), selectivity against opioid receptor κ, μ, and little inhibition for the hERG channel.
价 格:¥电议型 号:T6175产 地:中国大陆