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T61969AChE/BChE-IN-10
AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation.
价 格:¥电议型 号:T61969产 地:中国大陆
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TN6717chaetoglobosin Vbchaetoglobosin Vb
chaetoglobosin Vb is a new cytochalasan alkaloid isolated?from endophytic Chaetomium globosum
价 格:¥电议型 号:TN6717产 地:中国大陆
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T8647BCH001PARN,dyskeratosis,telomerase,stem,BCH 001,polynucleotide,TERC,rPAPD5,ncRNA,BCH001,polymerases,
BCH001 is a specific small-molecule inhibitor of PAPD5.
价 格:¥电议型 号:T8647产 地:中国大陆
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T6289DovitinibCHIR-258;TKI258;多韦替尼;度维替尼
Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to EGFR, InsR, EphA2, c-Met, IGF-1R, Tie2, and HER
价 格:¥电议型 号:T6289产 地:中国大陆
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T30908Chromotrope 2BChromotrope Red 4B;Chromotrope2B;C.I. Acid Red 176;Chromotrope-2B
Chromotrope 2B is a reagent for analytical determination of boric acid and borates, and is also used to produce a highly colored radical anion in conjuction with Chromotrope 2R.
价 格:¥电议型 号:T30908产 地:中国大陆
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T1936AlectinibCH5424802;RG-7853;AF-802;AF802;艾乐替尼
CH5424802 is an orally available inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with antineoplastic activity.
价 格:¥电议型 号:T1936产 地:中国大陆
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T11820LAT1-IN-12-氨基-2-去甲菠烷羧酸;BCH
LAT1-IN-1 (BCH) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis. is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1).
价 格:¥电议型 号:T11820产 地:中国大陆
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T0682Lamivudine拉米夫定;GR109714X;BCH-189
Lamivudine is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3´ carbon of the pentose ring. It is used to treat HIV disease.
价 格:¥电议型 号:T0682产 地:中国大陆
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T0259ChromocarbChromone-2-carboxylic acid;Chromocarbe;色烯卡
Chromocarb is a vascular protective agent used to treat venous disorders and microvascular affections.
价 格:¥电议型 号:T0259产 地:中国大陆
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T0682LamivudineLamivudine,BCH-189,GR109714X
Lamivudine is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3´ carbon of the pentose ring. It is used to treat HIV disease.
价 格:¥电议型 号:T0682产 地:美洲
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T11820LAT1-IN-1LAT1-IN-1,BCH,
LAT1-IN-1 (BCH) ?significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis.?is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1).
价 格:¥电议型 号:T11820产 地:美洲
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T2194Chicago Sky Blue 6BChicago Sky Blue 6B,Direct Blue 1,Pontamine sky blue
Chicago sky blue 6B, a vesicular glutamate transporters inhibitor, attenuates methamphetamine-induced hyperactivity and behavioral sensitization in mice.
价 格:¥电议型 号:T2194产 地:美洲
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T8647BCH001;化合物BCH001BCH001
BCH001 is a specific small-molecule inhibitor of PAPD5.
价 格:¥电议型 号:T8647产 地:中国大陆
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T82916BChE-IN-20;化合物 BChE-IN-20BChE-IN-20
BChE-IN-20 (compound 7c) is a potent, selective inhibitor of BChE, demonstrating IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE. It also inhibits P glycoprotein with an IC50 of 0.27 μM. As a promising template, BChE-IN-20 advances the design and development of pharmaceutical BChE-selective ligands, encompassing inhibitors and fluorogenic probes.
价 格:¥电议型 号:T82916产 地:中国大陆
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T82915BChE-IN-21;化合物 BChE-IN-21BChE-IN-21
BChE-IN-21, a potent inhibitor of butyrylcholinesterase (BChE), exhibits an inhibition constant (IC50) of 0.14 ± 0.02 μM, indicating promise for research in Alzheimer´s disease [1].
价 格:¥电议型 号:T82915产 地:中国大陆
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T82238HAPSBC;化合物 HAPSBCHAPSBC
HAPSBC, an S-benzyl iron chelator, modulates the intracellular distribution of ^59Fe [1].
价 格:¥电议型 号:T82238产 地:中国大陆
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T79966AChE/BChE-IN-14;化合物 AChE/BChE-IN-14AChE/BChE-IN-14
AChE/BChE-IN-14 (compound 13), a benzylisoquinoline alkaloid extracted from Fissistigma polyanthum roots, demonstrates inhibitory effects on both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), coupled with antioxidant properties. This compound is pertinent to Alzheimer’s disease research [1].
价 格:¥电议型 号:T79966产 地:中国大陆
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T79692BChE-IN-19;化合物 BChE-IN-19BChE-IN-19
BChE-IN-19 (Compound 7b), a para-substituted indone derivative, exhibits potent inhibitory activity against butyryl cholinesterase (BChE) with an IC50 value of 0.04 μM. It enhances cholinergic neurotransmission and has potential therapeutic application in Alzheimer´s disease [1].
价 格:¥电议型 号:T79692产 地:中国大陆
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T79548AChE/BChE-IN-13;化合物 AChE/BChE-IN-13AChE/BChE-IN-13
AChE/BChE-IN-13 (compound 5j) serves as a potent dual inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting half-maximal inhibitory concentrations (IC50) of 20.89 μM for AChE and 17.37 μM for BChE. This compound is applicable in research related to Alzheimer´s disease (AD) [1].
价 格:¥电议型 号:T79548产 地:中国大陆
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T79342BChE-IN-17;化合物 BChE-IN-17BChE-IN-17
BChE-IN-17 (compound 6n) is a potent, selective inhibitor of butyrylcholinesterase (BChE), demonstrating inhibitory half-maximal inhibitory concentrations (IC50s) of 10.5 nM for equine BChE (eqBChE) and 32.5 nM for human BChE (hBChE). It exhibits over 1000-fold greater selectivity for BChE compared to acetylcholinesterase (AChE), while also presenting low neurotoxicity and moderate neuroprotective effects [1].
价 格:¥电议型 号:T79342产 地:中国大陆