T7848PT-2385Inhibitor,inhibit,Hypoxia-inducible factors,HIF/HIF Prolyl-Hydroxylase,HIF-PH,PT 2385,HIFs,PT

PT-2385 is a selective HIF-2α inhibitor (Kd<50 nM).

价 格：￥电议型 号：T7848产 地：中国大陆

TP1559LZiconotide Acetate (107452-89-1 free base)analgesic,non-opioid,Ziconotide Acetate (107452891 free

Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.

价 格：￥电议型 号：TP1559L产 地：中国大陆

T27371FR-167356

FR-167356 is a specific inhibitor of a3 isoform vacuolar type H?-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush border membranes and macrophage microsomes. FR-167356 reduces bone metastasis of B16-F10 cells.

价 格：￥电议型 号：T27371产 地：中国大陆

T6675Sodium Picosulfateinhibit,Inhibitor,Sodium Picosulfate

Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion.

价 格：￥电议型 号：T6675产 地：中国大陆

TN12955-O-Caffeoylshikimic acidinhibit,5 O Caffeoylshikimic acid,Inhibitor,5OCaffeoylshikimic acid

5-O-Caffeoylshikimic acid shows anti-oxidative activity; it also shows anti-inflammatory activity, the underlying mechanism was associated with downregulation of nuclear factor-κB.

价 格：￥电议型 号：TN1295产 地：中国大陆

TP1881L1Pep 2-8 ammonium salt(1541011-97-5 free base)Pep 2 8 ammonium salt(1541011 97 5 free base),Pep 28 am

Pep 2-8 ammonium salt is Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.

价 格：￥电议型 号：TP1881L1产 地：中国大陆

TP1789LMalantide acetate(86555-35-3 free base)Malantide acetate(86555 35 3 free base),Malantide acetate(865

Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activity in vitro.

价 格：￥电议型 号：TP1789L产 地：中国大陆

TN1438beta-Amyrin acetateHMG-CoA,betaAmyrin acetate,LDL,Fungal,inhibit,Inhibitor,arthritic,hemolysis,antif

beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities.

价 格：￥电议型 号：TN1438产 地：中国大陆

T9192BIIB068ADME,inhibit,FcγR,Autoimmune,Bruton tyrosine kinase,TNFα,BIIB 068,ROS,Inhibitor,reversible,Bt

BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.

价 格：￥电议型 号：T9192产 地：中国大陆

TP1898HS024selective,melanocortin,intake,Inhibitor,Melanocortin Receptor,MC Receptor,HS-024,food,HS024,inh

Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.

价 格：￥电议型 号：TP1898产 地：中国大陆

TN1768IriflophenoneInhibitor,MCF-7,proliferation,Iriflophenone,cells,T-47D,inhibit

Iriflophenone?stimulates cells proliferation in?MCF-7 and T-47D human breast cancer.

价 格：￥电议型 号：TN1768产 地：中国大陆

T67749Fuzapladib

Fuzapladib (IS-741) is a phospholipase A2 inhibitor that can inhibits the expression of Mac-1, a cell adhesion molecule. Fuzapladib blocks activation of adhesion molecules (integrin) expressed on the inflammatory cell surface to prevent inflammatory cells from adhering to vascular endothelial cells and infiltrating tissue and to control exacerbation of pancreatitis.

价 格：￥电议型 号：T67749产 地：中国大陆

T67777Flaviviruses-IN-3

Flaviviruses-IN-3 (compound 87) is a potent inhibitor of flaviviruse. Flaviviruses-IN-3 could reduce the WNV (West Nile virus) protease activity, with a inhibition of 54%.

价 格：￥电议型 号：T67777产 地：中国大陆

TQ0015PRN1371inhibit,CSF1R,PRN 1371,Inhibitor,colony stimulating factor 1 receptor,c-Fms,CSF-1R,FGFR,CSF-1

PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).

价 格：￥电议型 号：TQ0015产 地：中国大陆

TN2100PratenseinInhibitor,Nuclear factor-kappaB,Nuclear factor-κB,cognitive,inhibit,BDNF,synapse,Pratensei

Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.

价 格：￥电议型 号：TN2100产 地：中国大陆

TP1882L1Orphanin FQ(1-11) acetate(178249-41-7 free base)Orphanin FQ(1 11) acetate(178249 41 7 free base),Orp

Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays analgesic properties in CD-1 mice.

价 格：￥电议型 号：TP1882L1产 地：中国大陆

T9743FEN1-IN-SC13FEN1 IN SC13,Inhibitor,FEN1INSC13,FEN-1-IN-SC13,inhibit

FEN1-IN-SC13 is a potent inhibitor of DNA fragmentation endonuclease 1 (FEN1)

价 格：￥电议型 号：T9743产 地：中国大陆

T6908NSC 228155Epidermal growth factor receptor,Histone Acetyltransferase,EGFR,HER1,HATs,inhibit,Inhibito

NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.

价 格：￥电议型 号：T6908产 地：中国大陆

T7815LAOD9604 acetate(221231-10-3 free base)AOD9604 acetate(221231103 free base),AOD-9604 acetate(221231-1

AOD9604 acetate is a potential anti-obesity peptide based on the human growth hormone.

价 格：￥电议型 号：T7815L产 地：中国大陆

Fr14055Compound Fr14055Compound Fr14055

价 格：￥电议型 号：Fr14055产 地：中国大陆