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  • T6756AMG 925CDK,AMG 925,Cluster of differentiation antigen 135,FLT3,Cyclin dependent kinase,inhibit,CD135

    AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively.

    价 格：￥电议型 号：T6756产 地：中国大陆

  • T7007UNC2025Inhibitor,inhibit,FLT3,leukemia,CD135,Fms like tyrosine kinase 3,acute,Cluster of differentia

    UNC-2025（ IC50 of 0.74 nM and 0.8 nM） is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.

    价 格：￥电议型 号：T7007产 地：中国大陆

  • T6S0033CrotonosideFLT3,Cluster of differentiation antigen 135,Crotonoside,inhibit,HDAC,Inhibitor,Histone de

    1. Crotonoside has much more active than adenosine in reducing the blood pressure in rabbits and cats, in decreasing the tone of isolated intestinal strips of the rabbit, guinea pig and hamster and in stimulating the isolated uterus of guinea pigs and hamsters. 2. Crotonoside inhibits the growth of S-18 and Ehrlich solid tumor in mice at the optimal doses of 96 mg/kg/day x 12 and 48 mg/kg/day x 12, with 1-T/C values of 65% and 6%, respectively.

    价 格：￥电议型 号：T6S0033产 地：中国大陆

  • T7673ATH686ATH686,inhibit,CD135,Inhibitor,Apoptosis,ATH-686,ATP-competitive,FLT3,antileukemic,Fms like ty

    ATH 686 is an potent and selective Inhibitor of FLT3.

    价 格：￥电议型 号：T7673产 地：中国大陆

  • T11299FLT3-IN-4

    FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3;?IC50=7 nM) inhibitor ,for treating acute myelogenous leukemia.

    价 格：￥电议型 号：T11299产 地：中国大陆

  • T9856FLT3-IN-10

    FLT3-IN-10 (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for the treatment of FLT3-mutated acute myeloid leukemia (AML).

    价 格：￥电议型 号：T9856产 地：中国大陆

  • T6138TCS 359FLT3 Inhibitor

    TCS 359 is a potent FLT3 inhibitor with IC50 of 42 nM.

    价 格：￥电议型 号：T6138产 地：中国大陆

  • T2051SKLB4771FLT3-?IN-?1；FLT3-IN-1

    FLT3-IN-1 is a novel potent and selective Flt3 inhibitor.

    价 格：￥电议型 号：T2051产 地：中国大陆

  • T1938FLT3-IN-2

    FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).

    价 格：￥电议型 号：T1938产 地：中国大陆

  • T11298FLT3-IN-3

    FLT3-IN-3 is an effective FLT3 inhibitor, and the IC50s of FLT3 WT and FLT3 D835Y are 13 and 8 nM, respectively.

    价 格：￥电议型 号：T11298产 地：中国大陆

  • T1938FLT3-IN-2FLT3-IN-2

    FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).

    价 格：￥电议型 号：T1938产 地：美洲

  • T2051FLT3-IN-1FLT3-IN-1,FLT3-?IN-?1,SKLB4771

    FLT3-IN-1 is a novel potent and selective Flt3 inhibitor.

    价 格：￥电议型 号：T2051产 地：美洲

  • T6138TCS 359TCS 359,FLT3 Inhibitor,

    TCS 359 is a potent FLT3 inhibitor with IC50 of 42 nM.

    价 格：￥电议型 号：T6138产 地：美洲

  • T82393FLT3/CHK1-IN-1；化合物 FLT3/CHK1-IN-1FLT3/CHK1-IN-1

    Compound 18, also known as FLT3/CHK-IN-1, is a dual inhibitor targeting FLT3 and CHK1, exhibiting over 1700-fold selectivity towards c-KIT and significantly diminishing hERG affinity, with an IC50 of 58.4 μM. It demonstrates efficacy in suppressing tumor growth in mouse xenotransplantation models implanted with MV-4-11 cells [1].

    价 格：￥电议型 号：T82393产 地：中国大陆

  • T82392FLT3-IN-23；化合物 FLT3-IN-23FLT3-IN-23

    FLT3-IN-23 (compound 15), a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3), exhibits an IC 50 value of 7.42 nM and demonstrates antiproliferative effects against BaF3 cells harboring diverse FLT3-TKD and FLT3-ITD-TKD mutations [1].

    价 格：￥电议型 号：T82392产 地：中国大陆

  • T79596FLT3-IN-20；化合物 FLT3-IN-20FLT3-IN-20

    FLT3-IN-20 (compound 34f) is a potent FLT3 inhibitor, demonstrating IC50 values of 1 nM for FLT3-D835Y and 4 nM for FLT3-ITD. It exhibits anti-proliferative effects on FLT3-ITD-positive AML cell lines, with IC50s of 7 nM in MV4-11 and 9 nM in MOLM-13, as well as 4 nM in a MOLM-13 variant harboring the FLT3-ITD-D835Y mutation. FLT3-IN-20 is utilized in cancer research [1].

    价 格：￥电议型 号：T79596产 地：中国大陆

  • T79420FLT3-IN-22；化合物 FLT3-IN-22FLT3-IN-22

    FLT3-IN-22 (compound 22f) is a potent inhibitor of FLT3, demonstrating IC50 values of 0.941 nM for FLT3 and 0.199 nM for the FLT3/D835Y mutant. This compound displays significant antiproliferative effects against MV4-11 cells and Ba/F3 cell lines expressing mutant FLT kinase variants, such as FLT-D835Y and FLT3-F691L [1].

    价 格：￥电议型 号：T79420产 地：中国大陆

  • T79391FLT3-IN-21；化合物 FLT3-IN-21FLT3-IN-21

    FLT3-IN-21 (compound LC-3), a potent FLT3 inhibitor with an IC50 value of 8.4 nM, induces apoptosis and arrests the cell cycle in the G1 phase. It effectively inhibits the proliferation of FLT3-ITD-positive AML cells MV-4-11, with an IC50 of 5.3 nM. In murine models, a daily dose of 10 mg/kg FLT3-IN-21 markedly inhibited tumor growth in the MV-4-11 xenograft model, achieving a tumor growth inhibition (TGI) of 92.16% [1].

    价 格：￥电议型 号：T79391产 地：中国大陆

  • T78176FLT3-IN-19；化合物 FLT3-IN-19FLT3-IN-19

    FLT3-IN-19 (Comp 50) is a potent, selective inhibitor of FLT3, demonstrating an IC50 value of 0.213 nM, and is applicable in research pertaining to acute myeloid leukemia (AML) [1].

    价 格：￥电议型 号：T78176产 地：中国大陆

  • T74707PROTAC FLT3/CDK9 degrader-1；化合物 PROTAC FLT3/CDK9 degrader-1PROTAC FLT3/CDK9 degrader-1

    PROTAC FLT3/CDK9 degrader-1, a potent dual degrader of FLT3 and CDK9, effectively induces apoptosis and targets protein degradation of FLT3 and CDK9. This compound holds research potential for FLT3-ITD mutated AML [1].

    价 格：￥电议型 号：T74707产 地：中国大陆

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