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T9353OXOMEMAZINEhistamine H1-receptor,OXOMEMAZINE,Histamine Receptor,inhibit,phenothiazine,antimuscarinic
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M1 receptors, showing high (Ki=84 nM, M1 receptors) and low (Ki=1.65 μM, M2 receptors) affinity sites 20 times the difference[1]. Oxomemazine is an antihistamine and anticholinergic agent used in studies related to cough studies[2].
价 格:¥电议型 号:T9353产 地:中国大陆
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T64347ALDH1A3-IN-3ALDH1A3IN3
ALDH1A3-IN-3 (compound 16) is a potent inhibitor of ALDH1A3, with an IC50 of 0.26 μM. ALDH1A3-IN-3 is also a good ALDH3A1 substrate. ALDH1A3-IN-3 can be used for the research of prostate cancer.
价 格:¥电议型 号:T64347产 地:中国大陆
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T9720T3Inh-1T3Inh1,T3Inh 1,inhibit,O-glycosylation,Inhibitor,T-3Inh-1,ppGalNAc-T3,breast cancer cells,FGF
T3Inh-1 is an effective and selective inhibitor of ppGalNAc-T3 with an IC50 of 7 ?M. T3Inh-1 prevents breast cancer cells. T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic side effects.
价 格:¥电议型 号:T9720产 地:中国大陆
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TQ0059Ilorasertibanti-tumor,H1299,Platelet-derived growth factor receptor,Inhibitor,ABT 348,antiproliferat
Ilorasertib (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: 7 nM, 3 nM, and 32 nM).
价 格:¥电议型 号:TQ0059产 地:中国大陆
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T8727TH1020interaction,inhibit,Bacterial,flagellin,TH-1020,TH1020,Toll-like Receptor (TLR),TLR5,protein-p
TH1020 is a novel Inhibitor of Toll-Like Receptor 5 (TLR5)/Flagellin Complex with promising activity (IC50 =0.85±0.12 μm) and specificity.
价 格:¥电议型 号:T8727产 地:中国大陆
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T8484JSH-150CDK,inhibit,Cyclin dependent kinase,Inhibitor,JSH150,JSH-150,JSH 150
JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).
价 格:¥电议型 号:T8484产 地:中国大陆
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T7798FGH10019FGH10019,FGH 10019,inhibit,Inhibitor,Fatty Acid Synthase (FASN)
FGH-10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM).
价 格:¥电议型 号:T7798产 地:中国大陆
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T38271TH1217
TH1217 is a potent and selective dCTPase pyrophosphatase 1 (dCTPase) inhibitor, with an IC50 of 47 nM. TH1217 enhances the cytotoxic effect of cytidine analogues in leukemia cells. TH1217 also could modulate SARS-Cov-2 interactors, so it shows activity of against COVID-19.
价 格:¥电议型 号:T38271产 地:中国大陆
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T118066CDK9 inhibitor HH1
CDK9 inhibitor HH1 is an inhibitor of the human CDK2-cyclin A2 complex with an IC50 value of 2 μM.
价 格:¥电议型 号:T118066产 地:中国大陆
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T8151MobocertinibAP-32788,Epidermal growth factor receptor,TAK-788,H1975,Inhibitor,Mobocertinib,HCC827,in
Mobocertinib is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agent
价 格:¥电议型 号:T8151产 地:中国大陆
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T7425RU-301inhibit,TAM,RU-301,NASH,cancer,TAM Receptor,Gas6,Axl,RU301,Inhibitor,RU 301,Tyro3,Mer,H1299,TG
RU-301 is a novel pan-tam inhibitor
价 格:¥电议型 号:T7425产 地:中国大陆
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TN1494Cimicifugoside H-1bone,Inhibitor,xyloside,Cimicifugoside H-1,resorption,Cimicifugoside H1,C. foetida
Cimicifugoside H1 shows the protective function to cerebral neuron during cerebral ischemia.
价 格:¥电议型 号:TN1494产 地:中国大陆
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TQ0219MK-8033bladder cancer,breast cancer,MK8033,EBC-1,H1993,MK 8033,MK-8033,anti-tumor,Inhibitor,GTL-16,r
MK-8033 is a new and selective dual ATP competitive c-Met/Ron inhibitor (IC50: 1 nM Wt c-Met).
价 格:¥电议型 号:TQ0219产 地:中国大陆
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T9880ZINC05007751HCT-15,NCI-H1299,PEO1,ovarian,Inhibitor,ZINC 05007751,inhibit,cells,ZINC05007751,NEK6,an
ZINC05007751 is an effective inhibitor of NIMA-related kinase NEK6 (IC50 = 3.4 μM). ZINC05007751 is very selective against NEK1 and NEK6 with no significant activity observed against NEK2, NEK7, and NEK9.
价 格:¥电议型 号:T9880产 地:中国大陆
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T9532MRT-81Smo,Smoothened,human,C3H10T1/2 cells,inhibit,Shh-light2 cells,rodent,BODIPY-cyclopamine,MRT81,
MRT-81 inhibits human and rodent smoothened?Smo?receptors effectively with an IC50?value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 also can be used for the research of cancer[1].
价 格:¥电议型 号:T9532产 地:中国大陆
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T60034TH1085Inhibitor,DNA glycosylase 1 (OGG1),TH-10785,TH 10785,DNA oxidative lesions,TH1085,enzyme,pheny
TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).
价 格:¥电议型 号:T60034产 地:中国大陆
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T9195SHR0302Th17,SHR-0302,B-cell,Inhibitor,inhibit,arthritis,collagen,migration,hepatic,SHR0302,JAK1,phos
SHR0302 is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2).
价 格:¥电议型 号:T9195产 地:中国大陆
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T35328H-1152 dihydrochlorideH 1152 dihydrochloride,H1152 dihydrochloride
H-1152 dihydrochloride is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM. H-1152 dihydrochloride inhibits PKA, PKC, PKG, Aurora A and CaMKII with IC50 values of 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.
价 格:¥电议型 号:T35328产 地:中国大陆
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T7611ODM-203anti-tumor immunity,ODM-203,FGFR,HUVEC,H1581,Inhibitor,cancer,Vascular endothelial growth fac
ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity
价 格:¥电议型 号:T7611产 地:中国大陆
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T8382Cariprazine hydrochlorideDopamine Receptor,Cariprazine,5-hydroxytryptamine Receptor,RGH188,Inhibitor
Cariprazine HCl is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively)
价 格:¥电议型 号:T8382产 地:中国大陆