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T61392NLRP3-IN-10
NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading to suppress activation of NLRP3 inflammasome.
价 格:¥电议型 号:T61392产 地:中国大陆
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T8595Practololreceptor,inhibit,arrhythmias,β1-adrenergic,Practolol,Beta Receptor,Adrenergic Receptor,card
Practolol is a selective β-adrenoceptor blocker.
价 格:¥电议型 号:T8595产 地:中国大陆
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T7604ValrubicinInhibitor,AD 32,AD32,Valrubicin,inhibit,PKC,Antibiotic,Protein kinase C
Valrubicin (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.
价 格:¥电议型 号:T7604产 地:中国大陆
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T8842IMT1BInhibitor,inhibit,POLRMT,oxidative,IMT-1B,LDC-203974,human,LDC 203974,anti-tumour,mtDNA,phospho
IMT1B is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression. It has anti-tumour effects.
价 格:¥电议型 号:T8842产 地:中国大陆
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T38563RaptinalRaptinal
Raptinal activates caspase-3 directly and initiates intrinsic caspase-dependent apoptosis pathway in multiple cell lines.
价 格:¥电议型 号:T38563产 地:中国大陆
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T6896TolimidoneSrc,Tolimidone,MLR 1023,MLR1023,Inhibitor,inhibit
MLR-1023 is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.
价 格:¥电议型 号:T6896产 地:中国大陆
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TQ0205Procyanidin B1Procyanidin B1,Toll-like Receptor (TLR),Inhibitor,Procyanidin B-1,inhibit,Procyanidin
Procyanidin B1, isolated from commonly eaten fruits, binds to the TLR4/MD-2 complex and has anti-inflammatory activity.
价 格:¥电议型 号:TQ0205产 地:中国大陆
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T9352hydrocotarnineE3 ligating enzyme,IL-18,NLRP3,E1/E2/E3 Enzyme,hydrocotarnine,inflammasome activation,
hydrocotarnine?is an inhibitor of Cbl.
价 格:¥电议型 号:T9352产 地:中国大陆
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T20692LSchistoflrfamide acetateSchistoflrfamide acetate
Schistoflrfamide acetate is isolated from the grasshopper, Schistocerca gregaria. Schistoflrfamide acetate elicited an immediate effect on the basal membrane potential of the opalescent tubule gland cells in insects.
价 格:¥电议型 号:T20692L产 地:中国大陆
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T8727TH1020interaction,inhibit,Bacterial,flagellin,TH-1020,TH1020,Toll-like Receptor (TLR),TLR5,protein-p
TH1020 is a novel Inhibitor of Toll-Like Receptor 5 (TLR5)/Flagellin Complex with promising activity (IC50 =0.85±0.12 μm) and specificity.
价 格:¥电议型 号:T8727产 地:中国大陆
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T83161V209cell,polysaccharides,IP-10,intravenous,MCP-1,Tumor,1V-209,IL-6,1V209,Toll-like Receptor (TLR),c
1V209 is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.
价 格:¥电议型 号:T8316产 地:中国大陆
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T14303Alrizomadlin
Alrizomadlin is an orally active inhibitor of MDM2 with IC50 of 3.8 nM and Ki of 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner.
价 格:¥电议型 号:T14303产 地:中国大陆
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T6S1256Ruscogenininhibit,Ruscogenin,Inhibitor,NOD-like Receptor (NLR)
1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV34) injured by tumor necrosis factor-alpha (TNF-alpha) in a concentration-dependent manner. 3. Ruscogenin significantly attenuate LPS-induced acute lung injury via inhibiting expressions of TF and iNOS and NF-kappa B p65 activation.
价 格:¥电议型 号:T6S1256产 地:中国大陆
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T7317CU-CPT-9aToll-like Receptor (TLR),inhibit,Inhibitor,CU CPT 9a,CUCPT9a
CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-
价 格:¥电议型 号:T7317产 地:中国大陆
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T6640RibitolRibitol,Endogenous Metabolite,inhibit,Inhibitor
Ribitol is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis.
价 格:¥电议型 号:T6640产 地:中国大陆
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T6887MCC950 sodiumCP 456773,MCC-950 sodium,MCC-950,inhibit,Inhibitor,CP456773,NOD-like Receptor (NLR),CRI
MCC950 sodium salt (IC50 of 7.5 uM in BMDMs) is an effective, selective NLRP3 inhibitor.
价 格:¥电议型 号:T6887产 地:中国大陆
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TP1904LFSLLRY-NH2 TFA(245329-02-6 free base)FSLLRY NH2 TFA(245329 02 6 free base),FSLLRY-NH-2 TFA(245329-02
FSLLRY-NH2 TFA is a is a protease-activated receptor 2 (PAR2) inhibitor. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.
价 格:¥电议型 号:TP1904L产 地:中国大陆
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TQ0165Arglabininflammasome,Ftase,anti-inflammatory,Farnesyl Transferase,antitumor,NOD-like Receptor (NLR),
Arglabin is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
价 格:¥电议型 号:TQ0165产 地:中国大陆
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T9276SBC-115337SBC115337,Serine endopeptidases,benzofuran,LDLR,Threonine proteases,SBC-115337,Ser/Thr Pro
SBC-115337 is a PCSK9 inhibitor.
价 格:¥电议型 号:T9276产 地:中国大陆
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T8503TLR4-IN-C34TLR4 IN C34,Toll-like Receptor (TLR),Inhibitor,TLR4INC34,inhibit,TLR-4-IN-C34
TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis
价 格:¥电议型 号:T8503产 地:中国大陆