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T9128N-DesmethyltrimipramineN Desmethyltrimipramine,NDesmethyltrimipramine
N-Desmethyltrimipramine is a biochemical.
价 格:¥电议型 号:T9128产 地:中国大陆
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T36061N-Desmethyl Sildenafil
N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor.
价 格:¥电议型 号:T36061产 地:中国大陆
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T9395(1S,4R)-N-Desmethyl Sertraline Hydrochloride(1S,4R) N Desmethyl Sertraline Hydrochloride,(1S,4R)NDes
(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.
价 格:¥电议型 号:T9395产 地:中国大陆
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T5158N-DesmethylclozapineN-去甲基氯氮平;Norclozapine;Normethylclozapine;Desmethylclozapine
N-Desmethylclozapine is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 receptors, an agonist at δ-opioid receptors.
价 格:¥电议型 号:T5158产 地:中国大陆
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T4281Endoxifen(E/Z)-Endoxifen;(E/Z)-N-desmethyl-4-hydroxy Tamoxifen;N-去甲基-4-羟基-
(E/Z)-Endoxifen is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for estrogen receptors than tamo
价 格:¥电议型 号:T4281产 地:中国大陆
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T19991N-desmethylmirtazapine米氮平杂质D;J1.061.658A;ORG3838;Normirtazapine;ORG 3838;N-Demethylmirtazapine;ORG-3
N-desmethylmirtazapine is a metabolite of mirtazapine. N-desmethylmirtazapine is also commonly used as an anxiolytic, hypnotic, antiemetic, and appetite stimulant.
价 格:¥电议型 号:T19991产 地:中国大陆
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T19450N-desmethyl Enzalutamide4-[3-[4-氰基-3-(三氟甲基)苯基]-5,5-二甲基-4-氧代-2-硫代-1-咪唑烷基]-2-氟苯甲酰胺;N-desmethyl MDV 310
N-desmethyl Enzalutamide is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the
价 格:¥电议型 号:T19450产 地:中国大陆
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T12148N-Desmethyltamoxifen hydrochloride
N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.
价 格:¥电议型 号:T12148产 地:中国大陆
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T12146N-Desmethyl-ApalutamideN-去甲基阿帕鲁胺杂质;N-Desmethyl Apalutamide
N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.
价 格:¥电议型 号:T12146产 地:中国大陆
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T12148N-Desmethyltamoxifen hydrochlorideN-Desmethyltamoxifen hydrochloride
N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.
价 格:¥电议型 号:T12148产 地:美洲
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T5158N-DesmethylclozapineN-Desmethylclozapine,Desmethylclozapine,Normethylclozapine
N-Desmethylclozapine is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 receptors, an agonist at δ-opioid receptors.
价 格:¥电议型 号:T5158产 地:美洲
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T5158N-Desmethylclozapine;N-去甲基氯氮平Desmethylclozapine|||Normethylclozapine|||Norclozapine;N-去甲基氯氮平|||Desme
N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 receptors, an agonist at δ-opioid receptors.
价 格:¥电议型 号:T5158产 地:中国大陆
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T4281Endoxifen;N-去甲基-4-羟基-(E/Z)-N-desmethyl-4-hydroxy Tamoxifen|||(E/Z)-Endoxifen;(E/Z)-N-desmethyl-4-hyd
(E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for estrogen receptors than tamoxifen. As the efficient conversion of tamoxifen to endoxifen depends on CYP2D6, polymorphisms in this CYP isoform can impact the effectiveness of TMX treatment.
价 格:¥电议型 号:T4281产 地:中国大陆
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T40504N-Desmethyl imatinib mesylate;N-Desmethyl imatinib mesylateImatinibmetaboliteN-Desmethylimatinibmesy
Norimatinib mesylate, also known as N-Desmethyl imatinib mesylate, is a metabolite derived from Imatinib, which acts as a potent multi-target inhibitor of v-Abl, c-Kit, and PDGFR.
价 格:¥电议型 号:T40504产 地:中国大陆
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T37979N-Desmethyl Pimavanserin;N-去甲基匹莫范色林AC-279;AC-279
N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin, a 5-HT2A receptor inverse agonist, which is used in the treatment of sleep disorders such as insomnia.
价 格:¥电议型 号:T37979产 地:中国大陆
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T36063N-desmethyl Zolmitriptan;N-desmethyl ZolmitriptanN-desmethyl Zolmitriptan
N-desmethyl Zolmitriptan (DZT) is an active metabolite of the serotonin (5-HT) receptor subtype 5-HT1B and 5-HT1D agonist zolmitriptan . DZT is an agonist of 5-HT1B receptors that induces contraction of isolated human cerebral arteries (EC50 = 100 nM).
价 格:¥电议型 号:T36063产 地:中国大陆
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T36062N-Desmethyl Sildenafil (citrate);N-Desmethyl Sildenafil (citrate)N-Desmethyl Sildenafil (citrate)
N-Desmethyl sildenafil is a major metabolite of sildenafil . N-Desmethyl sildenafil is formed via oxidative metabolism of sildenafil by the cytochrome (CYP) P450 isoforms CYP3A4, CYP3A5, and CYP3A7.
价 格:¥电议型 号:T36062产 地:中国大陆
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T36061N-Desmethyl Sildenafil;N-去甲基西地那非Desmethylsildenafil|||UK-103,320;Desmethylsildenafil|||UK-103,320
N-Desmethyl Sildenafil (UK-103,320) (Desmethylsildenafil) is a prominent metabolite of Sildenafil, a potent inhibitor of phosphodiesterase type 5 (PDE5).
价 格:¥电议型 号:T36061产 地:中国大陆
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T35718N-desmethyl Rosuvastatin (sodium salt hydrate);N-desmethyl Rosuvastatin (sodium salt hydrate)N-desme
N-desmethyl Rosuvastatin is an active metabolite of the HMG-CoA reductase inhibitor rosuvastatin .1,2N-desmethyl Rosuvastatin is formed when rosuvastatin undergoes demethylation, primarily by the cytochrome P450 (CYP) isoform CYP2C9 and to a lesser extent by CYP2C19 and CYP3A4.1
价 格:¥电议型 号:T35718产 地:中国大陆
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T35717N-desmethyl Rosiglitazone;N-desmethyl RosiglitazoneN-desmethyl Rosiglitazone
N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone , a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone.
价 格:¥电议型 号:T35717产 地:中国大陆