TQ0011PF-06869206inhibit,PF-06869206,Na+ channels,Sodium Channel,Na channels,PF 06869206,Inhibitor,PF06869

PF-06869206 is an oral selective inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1, IC50: 380 nM).

价 格：￥电议型 号：TQ0011产 地：中国大陆

T6834FCCPFCCP,inhibit,Mitochondrial Metabolism,Inhibitor

FCCP, a potent uncoupler of oxidative phosphorylation in mitochondria, transport protons across cell membranes leading to disrupts ATP synthesis.

价 格：￥电议型 号：T6834产 地：中国大陆

TN1108Kaempferol 3-O-sophorosideKaempferol 3 O sophoroside,Kaempferol 3Osophoroside,Inhibitor,inhibit

Kaempferol 3-O-beta-sophoroside has antibacterial and antiviral activities.

价 格：￥电议型 号：TN1108产 地：中国大陆

T6914Oclacitinib maleateOclacitinib,PF03394197,Oclacitinib maleate,inhibit,PF 03394197,Inhibitor,Janus ki

Oclacitinib is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 38 non-JAK kinases.

价 格：￥电议型 号：T6914产 地：中国大陆

T16845Sarolanerdog,Sarolaner,Parasite,PF 6450567,flea,Inhibitor,oral,inhibit,isoxazoline,tick,PF6450567

Sarolaner is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).

价 格：￥电议型 号：T16845产 地：中国大陆

T8880PFM01Inhibitor,derivative,MRE11,PFM-01,NHEJ,Mirin,DSB,endonuclease,N-alkylated,PFM01,PFM 01,inhibit

PFM01 is an inhibitor of MRE11 endonuclease. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR).

价 格：￥电议型 号：T8880产 地：中国大陆

TP1885L1[(pF)Phe4]Nociceptin(1-13)NH2 acetate[(pF)Phe4]Nociceptin(113)NH2 acetate,[(pF)Phe4]Nociceptin(1 13)

[(pF)Phe4]Nociceptin(1-13)NH2 acetate is a selective agonist of NOP receptor with a pKi of 10.68 and a pEC50 of 9.31. [(pF)Phe4]Nociceptin(1-13)NH2 acetate displays high selectivity over δ, κ, and μ opioid receptors (>3000 fold).

价 格：￥电议型 号：TP1885L1产 地：中国大陆

T8849PF-9601Nexcitotoxicity,neurodegenerative diseases,MAO,PF9601N,Monoamine Oxidase,MAO-B inhibitor,neur

PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.

价 格：￥电议型 号：T8849产 地：中国大陆

T8202Kaempferol 3-O-gentiobiosideKaempferol 3Ogentiobioside,inhibit,Kaempferol 3 O gentiobioside,Inhibito

Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. It possesses activity against α-glucosidase and displays a carbohydrate enzyme inhibitory effect (IC50: 50 μM).

价 格：￥电议型 号：T8202产 地：中国大陆

TQ0010Brepocitinibinhibit,Janus kinase,PF06700841,JAK,Brepocitinib,Inhibitor,PF 06700841

Brepocitinib is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits JAK2/3 (IC50s: 77 nM/6.49 μM).

价 格：￥电议型 号：TQ0010产 地：中国大陆

T9712PF07104091

PF-07104091 inhibits CDK2, which may lead to cell cycle arrest, induce apoptosis and inhibit tumor cell proliferation.

价 格：￥电议型 号：T9712产 地：中国大陆

T90611PF-03049423PF03049423,PF 03049423

价 格：￥电议型 号：T90611产 地：中国大陆

T41275PF-04753299PF04753299,PF 04753299

PF-04753299 is a potent and selective inhibitor of UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC). PF-04753299 is bactericidal for the gonococcal isolates. PF-04753299 inhibits E. coli, P. aeruginosa and K. pneumoniae strains with MIC 90 values of 2 μg/ml, 4 μg/ml and 16 μg/ml, respectively. PF-04753299 is used for the study of gram-negative bacteria infection [1].

价 格：￥电议型 号：T41275产 地：中国大陆

T9167PF-9363CTx-648,cancer,patient-derived,anti-tumor,HAT,CTx648,Inhibitor,HATs,selective,xenograft,CTx 6

PF-9363 is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer.

价 格：￥电议型 号：T9167产 地：中国大陆

T64337PF-04745637PF04745637,Inhibitor,bowel,TRPA1,disease,inhibit,respiratory,PF-04745637,Transient recept

PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].

价 格：￥电议型 号：T64337产 地：中国大陆

T7502LPF 05089771Na+ channels,diabetic,inhibit,Inhibitor,neuropathy,Sodium Channel,Na channels,TTX-R,PF 05

PF-05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent.

价 格：￥电议型 号：T7502L产 地：中国大陆

T12424PF-06305591

PF-06305591 is an effective and selective blocker of voltage-gated sodium channel NaV1.8 (IC50 = 15 nM).

价 格：￥电议型 号：T12424产 地：中国大陆

T16491PF-06446846 hydrochloridePF06446846 hydrochloride,PF 06446846 hydrochloride

PF-06446846 hydrochloride suppresses PCSK9 by inducing the ribosome to stall around codon 34. PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9.

价 格：￥电议型 号：T16491产 地：中国大陆

T9243PFI-90antitumor,Inhibitor,PFI 90,differentiation,PAX3-FOXO1,demethylase,PFI-90,apoptosis,histone,His

PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action.PFI-90 has the potential for the antitumor activity. PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased.

价 格：￥电议型 号：T9243产 地：中国大陆

T8767PfDHODH-IN-2malaria,Dihydroorotate Dehydrogenase,inhibit,PfDHODH,3D7,Inhibitor,Plasmodium falciparum

PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor . It is used an antimalarial agent and can be used for the research of malaria

价 格：￥电议型 号：T8767产 地：中国大陆