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T60919SARS-CoV-2-IN-13
SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide. SARS-CoV-2-IN-13 is more stable than niclosamide in human plasma and liver S9 enzymes assay. SARS-CoV-2-IN-13 can improve bioavailability and half-life when administered orally. SARS-CoV-2-IN-13 is a potent SARS-CoV-2 inhibitor with an IC 50 of 0.057 μM [1].
价 格：￥电议型 号：T60919产 地：中国大陆
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T81210SARS-CoV-2 Mpro-IN-12；化合物 SARS-CoV-2 Mpro-IN-12SARS-CoV-2 Mpro-IN-12
SARS-CoV-2 Mpro-IN-12 (compound D026) serves as an inhibitor of the main protease (Mpro) of SARS-CoV-2, exhibiting antiviral properties [1].
价 格：￥电议型 号：T81210产 地：中国大陆
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T81209SARS-CoV-2-IN-62；化合物 SARS-CoV-2-IN-62SARS-CoV-2-IN-62
SARS-CoV-2-IN-62 (Compound R3b) effectively inhibits SARS-CoV-2 replication in Vero E6 and Calu-3 cells, demonstrating low cytotoxicity and EC50 values of 2.97 μM and 3.82 μM, respectively [1].
价 格：￥电议型 号：T81209产 地：中国大陆
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T81208SARS-CoV-2-IN-63；化合物 SARS-CoV-2-IN-63SARS-CoV-2-IN-63
SARS-CoV-2-IN-63 (Compound R3e) serves as an inhibitor of SARS-CoV-2 replication, demonstrating low cytotoxicity. It effectively suppresses viral replication within Vero E6 cells and Calu-3 cells, yielding half-maximal effective concentration (EC50) values of 1.99 μM and 1.92 μM, respectively [1].
价 格：￥电议型 号：T81208产 地：中国大陆
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T81207SARS-CoV-2-IN-64；化合物 SARS-CoV-2-IN-64SARS-CoV-2-IN-64
SARS-CoV-2-IN-64 (compound 9), derived from chenodeoxycholic acid, serves as a potent inhibitor of the SARS-CoV-2 spike glycoprotein [1].
价 格：￥电议型 号：T81207产 地：中国大陆
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T81206SARS-CoV-2-IN-65；化合物 SARS-CoV-2-IN-65SARS-CoV-2-IN-65
SARS-CoV-2-IN-65 (compound 2f (81)) is a potent, orally active reversible inhibitor of SARS-CoV-2 entry, primarily obstructing the RBD:ACE2 interaction and TMPRSS2 activity within the ACE2-dependent pathway in Calu-3 cells [1].
价 格：￥电议型 号：T81206产 地：中国大陆
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T81205SARS-CoV-2-IN-66；化合物 SARS-CoV-2-IN-66SARS-CoV-2-IN-66
SARS-CoV-2-IN-66 (1), a derivative of vitamin K, functions as an inhibitor of SARS-CoV-2, exhibiting an effective concentration (EC50) of 70.8 μM in VeroE6/TMPRSS2 cells [1].
价 格：￥电议型 号：T81205产 地：中国大陆
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T81204SARS-CoV-2-IN-67；化合物 SARS-CoV-2-IN-67SARS-CoV-2-IN-67
SARS-CoV-2-IN-67 (Compound 16), a derivative of vitamin K, exhibits anti-SARS-CoV-2 properties, with an effective concentration (EC50) of 64.8 μM in VeroE6/TMPRSS2 cells, and inhibits SARS-CoV-2 RdRp activity [1].
价 格：￥电议型 号：T81204产 地：中国大陆
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T81203SARS-CoV-2-IN-68；化合物 SARS-CoV-2-IN-68SARS-CoV-2-IN-68
SARS-CoV-2-IN-68 (compound 6C) is a covalent inhibitor of both SARS-CoV-2 PLpro and Mpro, exhibiting potent antiviral properties by targeting the Zn-finger domain of PLpro [1].
价 格：￥电议型 号：T81203产 地：中国大陆
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T81202SARS-CoV-2-IN-69；化合物 SARS-CoV-2-IN-69SARS-CoV-2-IN-69
SARS-CoV-2-IN-69 (Compound 7E) is a potent, non-covalent inhibitor of the SARS-CoV-2 main protease (M^pro) with an EC50 of 7.4 μM and also inhibits the papain-like protease (PL^pro) [1].
价 格：￥电议型 号：T81202产 地：中国大陆
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T80657SARS-CoV-2 3CLpro-IN-15；化合物 SARS-CoV-2 3CLpro-IN-15SARS-CoV-2 3CLpro-IN-15
SARS-CoV-2 3CLpro-IN-15 (compound a), a beta-nitrostyrene derivative, acts as an inhibitor of the SARS-CoV-2 3CL protease (3CLpro), effectively inhibiting viral replication and transcription. It is instrumental in the identification of potential anti-COVID-19 lead compounds [1].
价 格：￥电议型 号：T80657产 地：中国大陆
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T80636SARS-CoV-2-IN-59；4-(4,5-二氢-2-咪唑基)苯腈SARS-CoV-2-IN-59
SARS-CoV-2-IN-59 (compound E07), an imidazoline derivative, is a non-peptide small molecule that inhibits SARS-CoV-2 by targeting its main protease (Mpro). It exhibits robust binding with Mpro residues (Met 165, Gln 166, Met 165, His 41, Gln 189) [1].
价 格：￥电议型 号：T80636产 地：中国大陆
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T79677SARS-CoV-2-IN-58；化合物 SARS-CoV-2-IN-58SARS-CoV-2-IN-58
SARS-CoV-2-IN-58 (Compound 21H) serves as an antiviral agent targeting SARS-CoV-2, demonstrating efficacy with an EC50 of 18 μM. It specifically inhibits the SARS-CoV-2 main protease (Mpro) with an IC50 value of 0.35 μM [1].
价 格：￥电议型 号：T79677产 地：中国大陆
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T79676SARS-CoV-2 3CLpro-IN-21；化合物 SARS-CoV-2 3CLpro-IN-21SARS-CoV-2 3CLpro-IN-21
SARS-CoV-2 3CLpro-IN-21 (Compound D6) is an irreversible, covalent inhibitor of SARS-CoV-2 3CL pro, demonstrating potent inhibition with an IC50 of 0.03 μM. Additionally, it exhibits inhibitory activity against SARS-CoV-1 3CL pro with an IC50 of 0.12 μM [1].
价 格：￥电议型 号：T79676产 地：中国大陆
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T79661SARS-CoV-2 3CLpro-IN-18；化合物 SARS-CoV-2 3CLpro-IN-18SARS-CoV-2 3CLpro-IN-18
SARS-CoV-2 3CLpro-IN-18 (Compound 3C) is a covalent inhibitor of SARS-CoV-2 3CLpro with an IC50 of 0.478 μM. It demonstrates inhibition of SARS-CoV-2 in Vero E6 cells, with an EC50 of 2.499 μM, and exhibits low cytotoxicity (CC50 > 200 μM) [1].
价 格：￥电议型 号：T79661产 地：中国大陆
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T79660SARS-CoV-2 3CLpro-IN-17；化合物 SARS-CoV-2 3CLpro-IN-17SARS-CoV-2 3CLpro-IN-17
Compound 3h, also known as SARS-CoV-2 3CLpro-IN-17, is a selective inhibitor of the SARS-CoV-2 3CL protease, demonstrating an IC50 of 0.322 μM [1].
价 格：￥电议型 号：T79660产 地：中国大陆
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T79659SARS-CoV-2 3CLpro-IN-16；SARS-CoV-2 3CLpro 抑制剂16SARS-CoV-2 3CLpro-IN-16
SARS-CoV-2 3CLpro-IN-16 is a covalent SARS-CoV-2 3CLpro inhibitor that inhibits 3CLpro activity and achieves its inhibitory effect by forming a covalent bond with Cys145.
价 格：￥电议型 号：T79659产 地：中国大陆
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T79570SARS-CoV-2-IN-55；化合物 SARS-CoV-2-IN-55SARS-CoV-2-IN-55
SARS-CoV-2-IN-55 (compound 65) is an inhibitor of SARS-CoV-2 exhibiting low cytotoxicity, characterized by an IC50 of 0.3 μM, effectuated through direct interaction with VSV-S pseudoparticles [1].
价 格：￥电议型 号：T79570产 地：中国大陆
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T79526SARS-CoV-2 nsp14-IN-4；化合物 SARS-CoV-2 nsp14-IN-4SARS-CoV-2 nsp14-IN-4
SARS-CoV-2 nsp14-IN-4 (Compound 12q), a non-cytotoxic and cell-permeable inhibitor of SARS-CoV-2 nsp14 methyltransferase (IC50 = 19 nM), is employed in COVID-19 research [1].
价 格：￥电议型 号：T79526产 地：中国大陆
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T79515SARS-CoV-2 Mpro-IN-10；化合物 SARS-CoV-2 Mpro-IN-10SARS-CoV-2 Mpro-IN-10
SARS-CoV-2 Mpro-IN-10 (27h) is a potent inhibitor of the Mpro enzyme, exhibiting IC50 and EC50 values of 10.9 nM and 43.6 nM, respectively. It is utilized in research focused on the SARS-CoV-2 virus [1].
价 格：￥电议型 号：T79515产 地：中国大陆
