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  • T16889SJ572403

    SJ572403 is an inhibitor of disordered protein p27 with Kd of 2.2 mM for specific regions within the D2 subdomain of p27-KID. SJ572403 can be used in studies about diseases with intrinsically disordered proteins.

    价 格：￥电议型 号：T16889产 地：中国大陆

  • T7678SJB2-043SJB2-043,inhibit,DUBs,SJB2043,SJB-2-043,SJB2 043,Deubiquitinase,Inhibitor

    SJB2-043 is an inhibitor of USP1-UAF1 ( IC50 : 544 nM).

    价 格：￥电议型 号：T7678产 地：中国大陆

  • T9117BSJ-4-116CDK,degrader,antiproliferative,inhibit,Kelly,C1039F,BSJ 4 116,Cyclin dependent kinase,PROTA

    BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation).

    价 格：￥电议型 号：T9117产 地：中国大陆

  • T6337RepSoxALK5 Inhibitor II；SJN 2511；E-616452

    RepSox is a potent and selective of the TGFβR-1/ALK5 inhibitor.

    价 格：￥电议型 号：T6337产 地：中国大陆

  • T5536SJA710-6

    SJA710-6 is a small molecule able to selectively differentiate MSCs toward hepatocyte-like cells.

    价 格：￥电议型 号：T5536产 地：中国大陆

  • T5395BSJ-03-123

    BSJ-03-123 is a potent, CDK6-selective small-molecule degrader.

    价 格：￥电议型 号：T5395产 地：中国大陆

  • T4662SJ000291942

    SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway. BMPs are members of the transforming growth factor beta (TGFβ) family of secreted signaling molecules.

    价 格：￥电议型 号：T4662产 地：中国大陆

  • T41257SJ6986

    SJ6986 is a chemical probe for studying the role of GSPT1/2 in vitro and in vivo. SJ6986 supports the utility of a diverse library of CRBN binders in the pursuit of targeting undruggable oncoproteins.

    价 格：￥电议型 号：T41257产 地：中国大陆

  • T16888SJ-172550

    SJ-172550 is a small molecule inhibitor of MDMX (EC50: 5 μM).

    价 格：￥电议型 号：T16888产 地：中国大陆

  • T12926SJB3-019ASJB3-019A

    SJB3-019A is a potent and novel inhibitor of USP1, 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells with IC50 of 0.0781 μM.

    价 格：￥电议型 号：T12926产 地：美洲

  • T4662SJ000291942SJ000291942

    SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway. BMPs are members of the transforming growth factor beta (TGFβ) family of secreted signaling molecules.

    价 格：￥电议型 号：T4662产 地：美洲

  • T5536SJA710-6SJA710-6

    SJA710-6 is a small molecule able to selectively differentiate MSCs toward hepatocyte-like cells.

    价 格：￥电议型 号：T5536产 地：美洲

  • T6337RepSoxRepSox,SJN 2511,E-616452

    RepSox is a potent and selective of the TGFβR-1/ALK5 inhibitor.

    价 格：￥电议型 号：T6337产 地：美洲

  • T83930SJ 11646；化合物 SJ 11646SJ 11646

    SJ 11646, a potent lymphocyte-specific protein tyrosine kinase (LCK) Degrader (PROTAC) with a DC50 of 0.00838 pM, utilizes Dasatinib as the LCK ligand and incorporates a phenyl glutarimide-based cereblon binder. Demonstrating cytotoxicity in both LCK-activated T cell acute lymphoblastic leukemia (T-ALL) cell lines and primary leukemia samples in vitro, SJ 11646 also exhibits anti-leukemic efficacy in vivo within patient-derived xenograft models of T-ALL.

    价 格：￥电议型 号：T83930产 地：中国大陆

  • T82507Ecleralimab；化合物 EcleralimabCSJ-117|||NVP-CSJ117；CSJ-117|||NVP-CSJ117

    Ecleralimab (CSJ-117; NVP-CSJ117), a Fab-IgG1-λ2 monoclonal antibody, selectively targets thymic stromal lymphopoietin (TSLP). It is typically produced using a Chinese Hamster Ovary (CHO) cell expression system [1].

    价 格：￥电议型 号：T82507产 地：中国大陆

  • T80760XSJ2-46；化合物 XSJ2-46XSJ2-46

    XSJ2-46, a 5´-amino NI analog, is an antiviral agent possessing anti-Zika virus properties and demonstrates reasonable inhibition of RNA-dependent RNA polymerases (RdRp), with an IC50 of 8.78 μM [1].

    价 格：￥电议型 号：T80760产 地：中国大陆

  • T79124JGK-068S；化合物 JGK-068SJGK-068S

    Compound I (JGK-068S) is a potent inhibitor of the epidermal growth factor receptor (EGFR) [1].

    价 格：￥电议型 号：T79124产 地：中国大陆

  • T78682SJ1461；化合物 SJ1461SJ1461

    SJ1461 is a potent, orally active inhibitor of the BET family, selectively targeting and inhibiting BRD2 (BD1), BRD2 (BD2), BRD4 (BD1), and BRD4 (BD2) with respective IC50 values of 1.6 nM, 0.1 nM, 6.5 nM, and 0.2 nM [1].

    价 格：￥电议型 号：T78682产 地：中国大陆

  • T77966SJPYT-195；化合物 SJPYT-195SJPYT-195

    SJPYT-195 is a cytotoxic agent targeting GSPT1 for degradation, suitable for PROTAC (PROteolysis TArgeting Chimera) synthesis [1].

    价 格：￥电议型 号：T77966产 地：中国大陆

  • T77944SJ1008030 formic；化合物 SJ1008030 formicSJ1008030 formic

    SJ1008030 (compound 8) formic is a selective JAK2 degrader within the PROTAC class, demonstrating efficacy in inhibiting MHH-CALL-4 leukemia cell growth with an IC50 value of 5.4 nM. It is potentially applicable for leukemia research [1].

    价 格：￥电议型 号：T77944产 地：中国大陆

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