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产品数:86101
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TN2275Tinnevellin glucosideTinnevellin glucoside,inhibit,Inhibitor
Tinnevellin glucoside is a natural product from Cassia angustifolia.
价 格:¥电议型 号:TN2275产 地:中国大陆
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TQ0150LevcromakalimPotassium Channel,KcsA,Inhibitor,inhibit,BRL38227,BRL-38227,Levcromakalim
Levcromakalim is an activator of the ATP-sensitive K+ channel.
价 格:¥电议型 号:TQ0150产 地:中国大陆
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T9192BIIB068ADME,inhibit,FcγR,Autoimmune,Bruton tyrosine kinase,TNFα,BIIB 068,ROS,Inhibitor,reversible,Bt
BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.
价 格:¥电议型 号:T9192产 地:中国大陆
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TP1898HS024selective,melanocortin,intake,Inhibitor,Melanocortin Receptor,MC Receptor,HS-024,food,HS024,inh
Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.
价 格:¥电议型 号:TP1898产 地:中国大陆
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T67777Flaviviruses-IN-3
Flaviviruses-IN-3 (compound 87) is a potent inhibitor of flaviviruse. Flaviviruses-IN-3 could reduce the WNV (West Nile virus) protease activity, with a inhibition of 54%.
价 格:¥电议型 号:T67777产 地:中国大陆
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TN2100PratenseinInhibitor,Nuclear factor-kappaB,Nuclear factor-κB,cognitive,inhibit,BDNF,synapse,Pratensei
Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.
价 格:¥电议型 号:TN2100产 地:中国大陆
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T8796CAN508inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,
CAN508 is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. It is also a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 μM, respectively.CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. Antitumor activity.
价 格:¥电议型 号:T8796产 地:中国大陆
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T9041AES-350Histone deacetylases,AES 350,MV4-11,AES-350,Apoptosis,acute myeloid leukemia,AML,Inhibitor,in
AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.
价 格:¥电议型 号:T9041产 地:中国大陆
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T6924Riviciclib hydrochlorideinhibit,Inhibitor,Riviciclib,CDK,Riviciclib hydrochloride,Cyclin dependent k
P276-00 is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.
价 格:¥电议型 号:T6924产 地:中国大陆
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T7596FirocoxibLPS,COX-2,fever,ML1785713,Cyclooxygenase,COX,inhibit,Firocoxib,Inhibitor,anti-inflammatory,
Firocoxib is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.
价 格:¥电议型 号:T7596产 地:中国大陆
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T8222SelpercatinibFVB/NRj mice,RET (WT),inhibit,Inhibitor,RET (G810R),LOXO 292,LOXO292,RET (V804M),Selper
Selpercatinib is a tyrosine kinase inhibitor with antineoplastic properties(IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively)
价 格:¥电议型 号:T8222产 地:中国大陆
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T7083GLPG1837GLPG-1837,ABBV 974,Cystic fibrosis transmembrane conductance regulator,Inhibitor,CFTR,Autoph
GLPG1837 is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.
价 格:¥电议型 号:T7083产 地:中国大陆
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T38163ML-148ML-148,ML 148,selective,Inhibitor,prostaglandin-signaling,15-PGDH,15-Hydroxyprostaglandin dehy
ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydrogenase or reductase enzymes and in studies about prostaglandin-signaling pathways.
价 格:¥电议型 号:T38163产 地:中国大陆
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T6874Lercanidipine hydrochlorideantihypertensive,Inhibitor,calcium,Lercanidipine,Lercanidipine hydrochlor
Lercanidipine is a calcium channel blocker of the dihydropyridine class.
价 格:¥电议型 号:T6874产 地:中国大陆
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T6683STF-62247renal,STF-62247,VHL,carcinoma,inhibit,cytotoxic,cell,RCC,Inhibitor,STF62247,intracytoplasmi
STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.
价 格:¥电议型 号:T6683产 地:中国大陆
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T17239VU0155069
VU0155069 strongly inhibits the invasive migration of several cancer cell lines in transwell assays. VU0155069 is a selective phospholipase D1 inhibitor (IC50: 46 nM in vitro).
价 格:¥电议型 号:T17239产 地:中国大陆
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T12163N6-(2-Phenylethyl)adenosineP1 receptor,A1AR,derivative,N-6-(2-Phenylethyl)adenosine,Adenosine Recept
N6-(2-Phenylethyl)adenosine is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM for rat and human A1.
价 格:¥电议型 号:T12163产 地:中国大陆
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T9240sulfopinneuroblastoma,antiproliferative,PIN1-3,tumors,cancer,pancreatic,Inhibitor,sulfopin,inhibit,c
Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
价 格:¥电议型 号:T9240产 地:中国大陆
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TP1722LPACAP (6-38), human, ovine, rat acetatePACAP (6 38), human, ovine, rat acetate(143748 18 9 Free base
PACAP (6-38), human, ovine, rat acetate is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2, respectively.
价 格:¥电议型 号:TP1722L产 地:中国大陆
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T80023-Hydroxycoumarinreproductive,metabolite,redox,sea,LOX,Inhibitor,Lipoxygenase,urchin,3-Hydroxycoumar
3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitors
价 格:¥电议型 号:T8002产 地:中国大陆