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产品数:86101
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T17875Pomalidomide-C2-NH2Inhibitor,E3 Ligase Ligand-Linker Conjugates,PomalidomideC2NH2,Pomalidomide-C-2-N
Pomalidomide-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a linker.
价 格:¥电议型 号:T17875产 地:中国大陆
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T7758Thalidomide-O-amido-PEG3-C2-NH2 TFAE3 Ligase Ligand-Linker Conjugates,Cereblon Ligand-Linker Conjuga
Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG3-C2-NH2 TFA incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T7758产 地:中国大陆
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T17881(S,R,S)-AHPC-C10-NH2PROTAC,(S,R,S) AHPC C10 NH2,Inhibitor,(S,R,S)AHPCC10NH2,E3 Ligase Ligand-Linker
(S,R,S)-AHPC-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC.
价 格:¥电议型 号:T17881产 地:中国大陆
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T9402Thalidomide-O-C4-NH2 hydrochlorideThalidomide O C4 NH2 hydrochloride,E3 Ligase Ligand-Linker Conjuga
Thalidomide-linker 9 is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
价 格:¥电议型 号:T9402产 地:中国大陆
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T8824CRBN modulator-1CRBN modulator1,CRBN modulator-1,inhibit,CRBN modulator 1,Ligands for E3 Ligase,E3 l
WUN29654 is a Thalidomide analog and CRBN modulator,has an IC50 of 3.5 μM and a Ki of 0.98 μM.
价 格:¥电议型 号:T8824产 地:中国大陆
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T73792-D08Ubiquitin ligase,Axl,2-D08,Tyro3,E3 ligating enzyme,Ubiquitin activating enzyme,Inhibitor,E1 ac
2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.
价 格:¥电议型 号:T7379产 地:中国大陆
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T9382Thalidomide-NH-C2-PEG3-OHinhibit,Inhibitor,Thalidomide-NH-C-2-PEG3-OH,E3 Ligase Ligand-Linker Conjug
Thalidomide-NH-C2-PEG3-OH is an E3 ligase ligand-linker conjugate.
价 格:¥电议型 号:T9382产 地:中国大陆
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TQ0127NavtemadlinNavtemadlin,MDM-2/p53,inhibit,Ubiquitin ligase,Ubiquitin activating enzyme,E3 ligating en
AMG 232 is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM). It binds to MDM2 with a Kd of 0.045 nM.
价 格:¥电议型 号:TQ0127产 地:中国大陆
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T7752(S,R,S)-AHPC-MeVHL ligand-2,VHL ligand2,Inhibitor,inhibit,Ligands for E3 Ligase,(S,R,S) AHPC Me,(S,R
(S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771. ARV-771 is a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.
价 格:¥电议型 号:T7752产 地:中国大陆
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TQ0231NVP-CGM097NVP-CGM097,Ubiquitin ligase,inhibit,MDM-2/p53,E3 ligating enzyme,NVP-CGM-097,CGM 097,Ubiqu
NVP-CGM097 is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).
价 格:¥电议型 号:TQ0231产 地:中国大陆
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T7760Thalidomide-O-amido-C3-NH2 TFAInhibitor,E3 Ligase Ligand-Linker Conjugates 52,E3 Ligase Ligand-Linke
Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-C3-NH2 TFA incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
价 格:¥电议型 号:T7760产 地:中国大陆
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T9291Thalidomide-5-OHLigands for E3 Ligase,PROTAC,Inhibitor,Thalidomide5OH,inhibit,CRBN,E3 ligase-recruit
Thalidomide-5-OH is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.
价 格:¥电议型 号:T9291产 地:中国大陆
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T9809E3 ligase Ligand 23inhibit,Inhibitor,Cereblon,Aiolos,ubiquitin proteasome,Ligands for E3 Ligase,Ikar
E3 ligase Ligand 23 is a cereblon binder and degrades Ikaros or Aiolos through ubiquitin proteasome.
价 格:¥电议型 号:T9809产 地:中国大陆
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T8561Apcinligase,pocket,anaphase-promoting,Apcin,recognition,complex,Inhibitor,Cdc20,Anaphase promoting c
Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. It acts by blocking mitotic exit and being synergistically amplified by co-addition of Ts-Arg-OMe.
价 格:¥电议型 号:T8561产 地:中国大陆
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T7753Thalidomide-O-COOHinhibit,Ligands for E3 Ligase,ThalidomideOCOOH,Inhibitor,Thalidomide O COOH,Cerebl
Thalidomide-O-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTACs.
价 格:¥电议型 号:T7753产 地:中国大陆
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T9389Thalidomide-PEG4-PropargylE3 Ligase Ligand-Linker Conjugates,Thalidomide-PEG-4-Propargyl,inhibit,Inh
Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker which can be used in PROTAC technology[1].
价 格:¥电议型 号:T9389产 地:中国大陆
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T8564BC-1382interaction,Anti-inflammatory,ligase,Inhibitor,lung,Ubiquitin,E1 activating enzyme,Ubiquitin
BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).
价 格:¥电议型 号:T8564产 地:中国大陆
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T18640(S,R,S)-AHPC-C4-NH2 hydrochlorideinhibit,E3 Ligase Ligand-Linker Conjugates,(S,R,S)AHPCC4NH2 hydroch
(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.
价 格:¥电议型 号:T18640产 地:中国大陆
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T8412(S,R,S)-AHPCInhibitor,inhibit,(S,R,S)AHPC,E3 ligase-recruiting Moiety,Ligands for E3 Ligase,(S,R,S)-
MDK7526 is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC is potential useful for the targeted degradation of the androgen receptor.
价 格:¥电议型 号:T8412产 地:中国大陆
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T7791IberdomideCELMoD,H929,CRBN,Ligands for E3 Ligase,KMS12PE,KMS11,orally,sub-G1,Apoptosis,Iberdomide,ce
Iberdomide is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
价 格:¥电议型 号:T7791产 地:中国大陆