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T16078Mirk-IN-1化合物 T16078Dyrk1B/A-IN-1
Mirk-IN-1 is an effective inhibitor of Dyrk1B(Mirk kianse) and Dyrk1A (IC50: 68±48 nM and 22±8 nM respectively).
价 格:¥电议型 号:T16078产 地:中国大陆
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T16018MB-07811;化合物MB-07811VK-2809;VK-2809
MB-07811 (VK-2809) is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity. MB-07811 is an agonist of liver-targeted THR-β.
价 格:¥电议型 号:T16018产 地:中国大陆
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T15978Mal-PEG2-acid;化合物 T15978Mal-PEG2-acid
Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin and its derivative cytotoxic molecule[1].
价 格:¥电议型 号:T15978产 地:中国大陆
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T15878m-PEG4-CH2COOH;化合物 T15878m-PEG4-CH2COOH
m-PEG4-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15878产 地:中国大陆
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T15825LY 178002;化合物 T15825LY 178002
LY 178002 is an effective inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2 (IC50: 0.6 μM for 5-lipoxygenase). LY 178002 also inhibits cellular production of LTB4 by human polymorphonuclear leukocytes and displays relatively weak inhibition on cyclooxygenase.
价 格:¥电议型 号:T15825产 地:中国大陆
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T15789LTURM34;化合物LTURM34LTURM34
LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM. LTURM34 displays effective antiproliferative activity in a wide range of tumor cell lines. LTURM34 shows 170-fold selectivity for DNA-PK over PI3K .
价 格:¥电议型 号:T15789产 地:中国大陆
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T15788LSZ-102;化合物LSZ-102LSZ102;LSZ102
LSZ-102 is an effective and selective degrader of estrogen receptor (IC50 = 0.2 nM) and can be used in studies about ERα positive breast cancer.
价 格:¥电议型 号:T15788产 地:中国大陆
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T15787LRE1;化合物LRE1LRE1
LRE1 is a specific and allosteric soluble adenylyl cyclase inhibitor.
价 格:¥电议型 号:T15787产 地:中国大陆
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T15786LPA2 antagonist 1;化合物 T15786LPA2 antagonist 1
LPA2 antagonist 1 is an LPA2 antagonist (IC50: 17 nM).
价 格:¥电议型 号:T15786产 地:中国大陆
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T15785LPA1 receptor antagonist 1;LPA1受体拮抗剂1LPA1 R antagonist 1;LPA1 R antagonist 1
LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopathic pulmonary fibrosis.
价 格:¥电议型 号:T15785产 地:中国大陆
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T15784LP99;化合物LP99LP99
LP99 is an epigenetic probe. LP99 disrupts the binding of BRD7 and BRD9 to chromatin in cells. LP99 is an effective and selective inhibitor of the BRD7 and BRD9 bromodomains (Kd: 99 nM against BRD9).
价 格:¥电议型 号:T15784产 地:中国大陆
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T15783LP117;化合物 T15783LP117
LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).
价 格:¥电议型 号:T15783产 地:中国大陆
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T15782Lp-PLA2-IN-1;化合物Lp-PLA2 -IN-1Lp-PLA2 inhibitor 1|||Lp-PLA2 -IN-1;Lp-PLA2 inhibitor 1|||Lp-PLA2 -IN-1
Lp-PLA2-IN-1 (Lp-PLA2 inhibitor 1) suppresses Lp-PLA2 activity processes for their preparation. Lp-PLA2-IN-1 (Lp-PLA2 inhibitor 1) also inhibits to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example, atherosclerosis, Alzheimer´s disease.
价 格:¥电议型 号:T15782产 地:中国大陆
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T15781LP-935509;化合物LP-935509LP-935509
LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure. LP-935509 is an effective inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of cyclin G-associated kinase(GAK, IC50=320 nM). LP-935509 is also a ATP-competitive inhibitor of adapter protein-2 associated kinase 1 (AAK1) (IC50 = 3.3 nM, Ki = 0.9 nM).
价 格:¥电议型 号:T15781产 地:中国大陆
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T15780LP-922761;化合物LP-922761LP-922761
LP-922761 is a potent, selective, and orally active AAK1 inhibitor with inhibitory effects on BMP-2 induced protein kinase (BIKE).
价 格:¥电议型 号:T15780产 地:中国大陆
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T1578Pargyline hydrochloride优降宁盐酸盐优降宁盐酸盐|||Pargylamine hydrochloride
Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.
价 格:¥电议型 号:T1578产 地:中国大陆
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T15778LP-533401化合物 T15778LP533401|||LP 533401
LP-533401 is an inhibitor of Tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut.
价 格:¥电议型 号:T15778产 地:中国大陆
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T15759Lintitript;林替曲特SR 27897;SR 27897|||林替曲特
Lintitript (SR 27897) is a selective antagonist of CCK1 with EC50s of 6 nM and 200 nM for CCK1 and CCK2. The Ki value is 0.2 nM for CCK1.
价 格:¥电议型 号:T15759产 地:中国大陆
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T15678KZR-504;化合物 T15678KZR-504
KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).
价 格:¥电议型 号:T15678产 地:中国大陆
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T15624JNJ-64619178;化合物JNJ-64619178JNJ-64619178
JNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM). It has effective activity In lung cancer.
价 格:¥电议型 号:T15624产 地:中国大陆