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T11508Camicinal;化合物 T11508GSK962040;GSK962040
Camicinal is a selective motilin receptor agonist (pEC50: 7.9).
价 格:¥电议型 号:T11508产 地:中国大陆
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T11507Guancydine化合物 T11507Guancidine
Guancydine is an antihypertensive agent.
价 格:¥电议型 号:T11507产 地:中国大陆
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T11506Guaiapate;愈创哌特Mg 5454|||Klamar;Mg 5454|||Klamar
Guaiapate has an antitussive and sedative effect.
价 格:¥电议型 号:T11506产 地:中国大陆
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T11505GSTO1-IN-1;化合物GSTO1-IN-1GSTO1-IN-1
GSTO1-IN-1 is a potent glutathione S-transferase omega 1 inhibitor (GSTO1; IC50: 31 nM).
价 格:¥电议型 号:T11505产 地:中国大陆
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T11504GSTO-IN-2;化合物 T11504GSTO-IN-2
GSTO-IN-2 is a glutathione S-transferase inhibitor (IC50s: 1.4, 16.3, and 3.6 μM for GSTP1-1, GSTM1, and GSTA2).
价 格:¥电议型 号:T11504产 地:中国大陆
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T11503GSK 690 Hydrochloride;化合物 T11503GSK 690 Hydrochloride
GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.
价 格:¥电议型 号:T11503产 地:中国大陆
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T11502Epelsiban;化合物 T11502GSK 557296;GSK 557296
Epelsiban is a selective and orally bioavailable oxytocin receptor antagonist (pKi: 9.9 for human oxytocin receptor).
价 格:¥电议型 号:T11502产 地:中国大陆
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T11500LGSK3368715 dihydrochlorideGSK3368715盐酸盐EPZ019997 dihydrochloride|||GSK3368715 2HCl|||EPZ019997 2HCl
GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active and potent inhibitor of type I protein arginine methyltransferases (PRMTs) with anticancer and antitumor activity, inhibiting PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, and can be used to study advanced solid tumors.
价 格:¥电议型 号:T11500L产 地:中国大陆
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T11500GSK3368715;化合物 T11500EPZ019997;EPZ019997
GSK3368715 is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50s: 3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). It has strong anti-cancer activity.
价 格:¥电议型 号:T11500产 地:中国大陆
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T11488GSK2850163;化合物GSK2850163GSK2850163
GSK2850163 is a novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1α) which can inhibit RNase activity and IRE1α kinase activity (IC50s: 200 and 20 nM).
价 格:¥电议型 号:T11488产 地:中国大陆
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T11482GSK2245035;化合物 T11482GSK2245035
GSK2245035 is a highly selective intranasal TLR7 agonist with preferential Type-1 interferon (IFN)-stimulating properties (pEC50s: 9.3 and 6.5 for IFNα and TFNα). It effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures.
价 格:¥电议型 号:T11482产 地:中国大陆
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T11450Gosogliptin;化合物 T11450PF-00734200|||PF-734200;PF-00734200|||PF-734200
Gosogliptin is a potent and selective dipeptidyl peptidase-IV (DPP-IV) inhibitor.
价 格:¥电议型 号:T11450产 地:中国大陆
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T11440GNE-8505;化合物 T11440GNE-8505
GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK).
价 格:¥电议型 号:T11440产 地:中国大陆
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T11408Orforglipron;奥格列隆LY3502970|||GLP-1 receptor agonist 1;LY3502970|||GLP-1 receptor agonist 1
Orforglipron (LY3502970; GLP-1 receptor agonist 1) is an orally available glucagon-like peptide (GLP-1) receptor agonist for the study of obesity and type 1 diabetes in adults.
价 格:¥电议型 号:T11408产 地:中国大陆
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T11401GKA50;化合物 T11401GKA50
GKA50 stimulates insulin release from mouse islets of Langerhans and MIN6 cells. GKA50 shows significant glucose lowering in high fat fed female rats. GKA50 is a potent glucokinase activator (EC50=33 nM at 5 mM glucose).
价 格:¥电议型 号:T11401产 地:中国大陆
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T11388Gemilukast;吉鲁司特ONO-6950;ONO-6950
Gemilukast (ONO-6950) is an orally active and potent dual inhibitor of cysteinyl leukotriene 1 and 2 receptors (CysLT1 and CysLT2), inhibits LTC 4-induced bronchoconstriction, and is inhibitory to human CysLT1 and CysLT2, and may be used in the treatment of asthma.
价 格:¥电议型 号:T11388产 地:中国大陆
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T11350GABAB receptor antagonist 1;化合物 T11350GABAB receptor antagonist 1
(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors.
价 格:¥电议型 号:T11350产 地:中国大陆
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T11344G150;化合物G150G150
G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).
价 格:¥电议型 号:T11344产 地:中国大陆
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T11343G0507;化合物 T11343G0507
G0507 is a pyrrolopyrimidinedione compound that serves as a potent inhibitor of Escherichia coli growth, effectively inducing the extracytoplasmic σE stress response. It acts as a valuable chemical probe, specifically designed to dissect lipoprotein trafficking in Gram-negative bacteria. Notably, G0507 demonstrates strong inhibitory activity against the LolCDE ABC Transporter.
价 格:¥电议型 号:T11343产 地:中国大陆
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T11250Ezetimibe-d4;化合物 T11250SCH 58235 D4;SCH 58235 D4
Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activation of Nrf2.
价 格:¥电议型 号:T11250产 地:中国大陆