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T1083Theophylline;茶碱Theo-24|||1,3-Dimethylxanthine;Theo-24|||1,3-Dimethylxanthine|||茶碱
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3´, 5´-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
价 格:¥电议型 号:T1083产 地:中国大陆
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T10783CGS 15435;化合物CGS 15435CGS 15435
CGS 15435 is a potent thromboxen (TxA2) synthetase inhibitor (IC50: 1 nM). CGS 15435 acts on PGI2 synthase, cyclooxygenase and liposynthase with much less selectivity than on thromboxin synthase.
价 格:¥电议型 号:T10783产 地:中国大陆
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T10683Carmoxirole hydrochloride;卡莫昔罗EMD 45609 hydrochloride;EMD 45609 hydrochloride|||卡莫昔罗
Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.
价 格:¥电议型 号:T10683产 地:中国大陆
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T10552Bitopertin (R enantiomer);化合物 T10552RO4917838 (R enantiomer)|||RG1678 (R enantiomer)|||Bitopertin R
Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a noncompetitive glycine reuptake inhibitor and inhibits glycine uptake at human GlyT1 (IC50: 25 nM).
价 格:¥电议型 号:T10552产 地:中国大陆
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T1054Tolbutamide;甲苯磺丁脲HLS 831;甲苯磺丁脲|||HLS 831
Tolbutamide (HLS 831) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.
价 格:¥电议型 号:T1054产 地:中国大陆
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T10531BGB-102;化合物 BGB-102JNJ-26483327;JNJ-26483327
BGB-102 (JNJ-26483327) is a kinase inhibitor targeting FLT3 and YES1 and an antagonist targeting EGFR and VEGFR3, which may be useful in the study of macular degeneration and diseases associated with genetic disorders and malformations.
价 格:¥电议型 号:T10531产 地:中国大陆
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T10483Lisaftoclax;化合物LisaftoclaxBcl-2/Bcl-xl inhibitor 1|||APG-2575;Bcl-2/Bcl-xl inhibitor 1|||APG-2575
Lisaftoclax (Bcl-2/Bcl-xl inhibitor 1) is an oral dual inhibitor of Bcl-2 and Bcl-xl, with IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively. Lisaftoclax is used to treat chronic lymphocytic leukemia (CLL) by inhibiting the action of the BCL-2 protein, which promotes the death of leukemia cells.
价 格:¥电议型 号:T10483产 地:中国大陆
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T10442A 83-01 sodium salt;化合物 T10442A 83-01 sodium salt
A 83-01 sodium salt is a potent inhibitor of TGF-β type I receptor ALK5 kinase, ALK4 and ALK7, with IC 50 s of 12 nM, 45 nM and 7.5 nM against the ALK5, ALK4 and ALK7 induced transcription, respectively [1].
价 格:¥电议型 号:T10442产 地:中国大陆
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T10383Asatone;细辛酮Asatone
Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.
价 格:¥电议型 号:T10383产 地:中国大陆
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T103187Compound 0833-0158;化合物 0833-0158Compound 0833-0158
Compound 0833-0158 is a useful organic compound for research related to life sciences and the catalog number is T103187.
价 格:¥电议型 号:T103187产 地:中国大陆
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T10283ALK-IN-5;化合物 T10283ALK-IN-5
ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK, IC50: 2.9 nM).
价 格:¥电议型 号:T10283产 地:中国大陆
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T10264AGN 192836;化合物 T10264AGN 192836
AGN 192836 is a potent and selective α2 adrenergic agonist (EC50s: 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor).
价 格:¥电议型 号:T10264产 地:中国大陆
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T10244ACY-1083;化合物ACY-1083ACY-1083
ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM) and effectively reverses chemotherapy-induced peripheral neuropathy.
价 格:¥电议型 号:T10244产 地:中国大陆
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T10219ABBV-4083;化合物 T10219ABBV-4083
ABBV-4083 is a Tylosin A analog that has potent anti-Wolbachia and anti-filarial activity.
价 格:¥电议型 号:T10219产 地:中国大陆
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T10217Abarelix Acetate (183552-38-7 free base);化合物 T10217PPI 149 Acetate|||Abarelix Acetate;PPI 149 Acetat
Abarelix (PPI 149; R 3827) Acetate is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research.
价 格:¥电议型 号:T10217产 地:中国大陆
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T1021(R)-Lansoprazole;右旋兰索拉唑Dexlansoprazole|||T 168390|||TAK 390|||R-(+)-Lansoprazole;Dexlansoprazole|||右
(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity.Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)
价 格:¥电议型 号:T1021产 地:中国大陆
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T101836-Methoxytricin;6-甲氧基哌啶6-Methoxytricin
6-Methoxytricin, a flavonoid isolated from Centella asiatica, is an inhibitor of aldose reductase (AR) and advanced glycosylation end-products (AGE), and inhibits T-cell proliferation and activation in biologic cells.
价 格:¥电议型 号:T10183产 地:中国大陆
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T10083Desethyl KBT-3022;化合物 T10083Desethyl KBT-3022|||Desethyl KBT3022|||Desethyl KBT3022|||Desethyl KBT 3
Desethyl KBT-3022 is an active metabolite of the antiplatelet compound KBT-3022.
价 格:¥电议型 号:T10083产 地:中国大陆
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T0983LDL-PenicillamineDL-青霉胺3-Sulfanylvaline|||DL-青霉胺
DL-Penicillamine (3-Sulfanylvaline) is a chelating agent recommended for the removal of excess copper in patients with Wilson´s disease. DL-Penicillamine is only found in individuals that have used or taken this drug. It is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson´s disease. From in vitro studies which indicate that one atom of copper combines with two molecules of DL-penicillamine. DL
价 格:¥电议型 号:T0983L产 地:中国大陆
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T0983Penicillamine青霉胺青霉胺|||d-penicillamin|||Dimethyl Cysteine|||D-青霉胺|||Artamine|||D-(-)-Penicillamine
Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl analog of the amino acid cysteine. As a degradation product of penicillin antibiotics, Artamine chelates with heavy metals and increases their urinary excretion.
价 格:¥电议型 号:T0983产 地:中国大陆