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T18070Lenalidomide-propargyl-C2-NH2 hydrochloride;化合物 T18070Lenalidomide-propargyl-C2-NH2 hydrochloride
Lenalidomide-propargyl-C2-NH2 hydrochloride is a compound that features a cereblon (CRBN) ligand for the E3 ubiquitin ligase, as well as a linker. It is utilized in the development of the PROTAC MD-224[1] system.
价 格:¥电议型 号:T18070产 地:中国大陆
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T18069Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride;化合物 T18069Lenalidomide-propargyl-C2-amido-Ph-NH
Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride is a chemical compound that features a cereblon (CRBN) ligand, functioning as an E3 ubiquitin ligase, along with a linker. It can be utilized to create the PROTAC MD-224[1].
价 格:¥电议型 号:T18069产 地:中国大陆
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T1796Otenabant hydrochloride;奥替那班Otenabant (CP-945598) HCl|||CP 945598 Hydrochloride|||Otenabant;奥替那班|||O
Otenabant hydrochloride (Otenabant) (CP-945598) is a competitive, high affinity, selective antagonist of the CB1 receptor (Ki: 0.7 nM).
价 格:¥电议型 号:T1796产 地:中国大陆
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T17924(S,R,S)-AHPC-PEG2-NH2 hydrochloride;化合物(S,R,S)-AHPC-PEG2-NH2 盐酸盐VH032-PEG2-NH2 hydrochloride|||VHL L
(S,R,S)-AHPC-PEG2-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 hydrochloride incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTAC.
价 格:¥电议型 号:T17924产 地:中国大陆
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T17922(S,R,S)-AHPC-PEG3-NH2 hydrochloride;化合物T17922VHL Ligand-Linker Conjugates 1 hydrochloride|||E3 ligas
(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC-based VHL ligand and 3-unit PEG linker.
价 格:¥电议型 号:T17922产 地:中国大陆
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T1791LCeritinib dihydrochloride;双盐酸盐色瑞替尼LDK378 dihydrochloride;LDK378 dihydrochloride|||双盐酸盐色瑞替尼
Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable and ATP-competitive inhibitor of ALK tyrosine kinase(IC50 of 200 pM), and also inhibits IGF-1R, InsR, and STK22D (IC50 values of 8, 7, and 23 nM, respectively), shows great antitumor potency
价 格:¥电议型 号:T1791L产 地:中国大陆
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T17890cIAP1 Ligand-Linker Conjugates 2 Hydrochloride;化合物 T17890E3 ligase Ligand-Linker Conjugates 37 Hydro
cIAP1 Ligand-Linker Conjugates 2 Hydrochloride is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is utilized in the creation of SNIPERs[1].
价 格:¥电议型 号:T17890产 地:中国大陆
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T17888cIAP1 Ligand-Linker Conjugates 6 hydrochloride;化合物 T17888E3 ligase Ligand-Linker Conjugates 35 hydro
cIAP1 Ligand-Linker Conjugates 6 hydrochloride is a compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. It is utilized for the purpose of designing SNIPERs[1].
价 格:¥电议型 号:T17888产 地:中国大陆
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T17886cIAP1 Ligand-Linker Conjugates 15 hydrochloride;化合物 T17886E3 ligase Ligand-Linker Conjugates 34 hydr
cIAP1 Ligand-Linker Conjugates 15 hydrochloride is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is useful in the development of SNIPERs[1].
价 格:¥电议型 号:T17886产 地:中国大陆
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T17884cIAP1 Ligand-Linker Conjugates 11 Hydrochloride;化合物 T17884E3 ligase Ligand-Linker Conjugates 33 Hydr
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. It is primarily utilized in the development of SNIPERs, a molecular tool for targeted protein degradation[1].
价 格:¥电议型 号:T17884产 地:中国大陆
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T17878Lenalidomide-C4-NH2 hydrochloride;化合物 T17878Cereblon ligand 1 hydrochloride|||E3 ligase Ligand-Linke
Lenalidomide-C4-NH2 hydrochloride is a Cereblon ligand derived from Lenalidomide. It serves as a recruiting agent for the CRBN protein. The compound, known as PROTAC (Compound 24), can be formed by linking Lenalidomide-C4-NH2 hydrochloride to the ligand for the protein. It exhibits inhibitory effects with IC50s of 0.98 nM and 13.7 nM against the growth of RS4;11 and MOLM-13 acute leukemia cell lines, respectively[1].
价 格:¥电议型 号:T17878产 地:中国大陆
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T1786Daclatasvir dihydrochloride;盐酸达拉他韦BMS-790052 dihydrochloride;BMS-790052 dihydrochloride|||盐酸达拉他韦
Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is an orally available antiviral agent that inhibits the NS5A region of the hepatitis C virus (HCV) and is used in combination with other oral antiviral agents to treat chronic hepatitis C. Elevations in serum enzyme levels during daclatasvir therapy are uncommon, and it has yet to be convincingly implicated in cases of clinically apparent liver injury with jaundice.
价 格:¥电议型 号:T1786产 地:中国大陆
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T1778AT7519 Hydrochloride;化合物AT 7519 hydrochloride saltAT7519 HCl|||AT 7519 hydrochloride salt;AT7519 HCl
AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.
价 格:¥电议型 号:T1778产 地:中国大陆
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T1776LPlerixafor octahydrochloride;盐酸普乐沙福JM3100 octahydrochloride|||Plerixafor 8HCl (AMD3100 8HCl)|||Pleri
Plerixafor octahydrochloride (JM3100 octahydrochloride) blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow and HSC movement into the peripheral circulation. Plerixafor is a bicyclam with hematopoietic stem cell-mobilizing activity.
价 格:¥电议型 号:T1776L产 地:中国大陆
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T17736Cy5-PEG5-amine hydrochloride;化合物 T17736Cy5-PEG5-amine hydrochloride
Cy5-PEG5-amine (hydrochloride) is a PEG-derived PROTAC linker employed for PROTAC synthesis[1].
价 格:¥电议型 号:T17736产 地:中国大陆
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T1761PD153035 hydrochloride;化合物PD153035 hydrochlorideZM 252868 HCl|||AG 1517|||Tyrphostin AG 1517|||SU 52
PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR (Ki: 5.2 pM, IC50: 29 pM); few influence against FGFR, PGDFR, InsR, CSF-1, and Src.
价 格:¥电议型 号:T1761产 地:中国大陆
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T17449APN-PEG4-Amine hydrochloride;化合物 T17449APN-PEG4-Amine hydrochloride
APN-PEG4-Amine (hydrochloride) is a cleavable four-unit polyethylene glycol (PEG) linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17449产 地:中国大陆
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T1735Lurasidone hydrochloride;盐酸鲁拉西酮Lurasidone HCl|||SM-13496 (Hydrochloride)|||SM-13496;Lurasidone HCl||
Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist, serotonin 5-HT7 receptor antagonist, an antagonist of the adrenergic α2A and α2C receptors, as well as a partial serotonin 5-HT1A receptor agonist. It is used in the treatment of schizophrenia and bipolar disorder.
价 格:¥电议型 号:T1735产 地:中国大陆
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T1732Semicarbazide hydrochloride;盐酸氨基脲Aminourea hydrochloride;盐酸氨基脲|||Aminourea hydrochloride
Semicarbazide hydrochloride (Aminourea hydrochloride) is Snow white crystals and used as a reagent for ketones and aldehydes with which it affords crystalline compounds having characteristic melting points.
价 格:¥电议型 号:T1732产 地:中国大陆
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T1731TAME hydrochlorideNA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐NA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐|||Tos-Arg-OMe HCl|||TOS-ARG-OME hydrochlo
TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.
价 格:¥电议型 号:T1731产 地:中国大陆