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T11796LL-Moses;化合物 T11796LL-45;L-45
L-45 is the first potent and cell-active bromodomain (Brd) inhibitor of p300/CBP-associated factor (PCAF) (Kd: 126±15 nM).
价 格:¥电议型 号:T11796L产 地:中国大陆
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T11795L-4-Oxalysine hydrochloride;L-4-噁溶菌素盐酸盐L-4-Oxalysine hydrochloride
L-4-Oxalysine hydrochloride has shown antitumor activities, is a natural product isolated from the culture media of Streptomyces roseovirdofuscus in China.
价 格:¥电议型 号:T11795产 地:中国大陆
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T11794L-368,899 hydrochloride;化合物 T11794L-368,899 hydrochloride
L-368,899 hydrochloride, used as a tocolytic agent, is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively.
价 格:¥电议型 号:T11794产 地:中国大陆
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T11793KY-05009;化合物KY-05009KY-05009
KY-05009 is a chemical compound that effectively suppresses TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells, reduces TNIK protein expression and the transcriptional activity of Wnt target genes, and promotes apoptosis in cancer cells, displaying anti-cancer properties. Furthermore, it functions as an ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with a Ki of 100 nM.
价 格:¥电议型 号:T11793产 地:中国大陆
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T11792KW-8232 free base;化合物 T11792KW-8232 free base
KW-8232 free base can reduces the biosynthesis of PGE2, is an anti-osteoporotic agent.
价 格:¥电议型 号:T11792产 地:中国大陆
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T11791KW-6055;化合物 T11791KW-6055
KW-6055 has anti-amnesic activity, is a benzylpyridine derivative.
价 格:¥电议型 号:T11791产 地:中国大陆
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T11790Kv3 modulator 4;化合物 T11790Kv3 modulator 4
Kv3 modulator 4 is a Kv3.1 (pEC50=5.45) and Kv3.2 modulator .Cyclobutyl structure.
价 格:¥电议型 号:T11790产 地:中国大陆
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T1179Tiotropium bromide噻托溴铵Tiopropium|||噻托溴铵|||BA679 BR
Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical application it acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation, thus producing a bronchodilatory effect.
价 格:¥电议型 号:T1179产 地:中国大陆
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T11779KRas G12C inhibitor 4;化合物 T11779KRas G12C inhibitor 4
KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.
价 格:¥电议型 号:T11779产 地:中国大陆
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T11723LJNJ-39758979;化合物JNJ-39758979JNJ-39758979
JNJ-39758979 is a selective and high-affinity histamine H4 receptor antagonist (Kis: 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively). JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells.
价 格:¥电议型 号:T11723L产 地:中国大陆
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T1170Olopatadine hydrochloride;盐酸奥洛他定Olopatadine HCl|||KW4679|||ALO4943A;盐酸奥洛他定|||Olopatadine HCl|||KW467
Olopatadine hydrochloride (ALO4943A) is an antihistamine with mast-cell stabilizing properties used as eye drops in the treatment of ALLERGIC CONJUNCTIVITIS.
价 格:¥电议型 号:T1170产 地:中国大陆
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T1166Ellipticine;玫瑰树碱NSC 71795|||Elliptisine;玫瑰树碱|||NSC 71795|||Elliptisine
Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-60, Breast adenocarcinoma MCF-7, Breast adenocarcinoma MCF-7, Leukemia HL-60, Neuroblastoma IMR-32, Neuroblastoma UKF-NB-4, Neuroblastoma UKF-NB-3, and Glioblastoma U87 mg cell, respectively.
价 格:¥电议型 号:T1166产 地:中国大陆
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T11595IACS-8779;化合物 T11595IACS-8779
IACS-8779 is a potent STING agonist that efficiently stimulates interferon gene activity and exhibits strong systemic antitumor effects.
价 格:¥电议型 号:T11595产 地:中国大陆
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T11579HSL-IN-3;化合物HSL-IN-3HSL inhibitor 3|||Ethyl 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate;HSL inh
HSL-IN-3 (HSL inhibitor 3) is a boronic acid derivative that is an inhibitor of hormone-sensitive lipase(HSL).
价 格:¥电议型 号:T11579产 地:中国大陆
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T11574HS79;化合物 T11574HS79
HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids (IC50: 1.57 μM).
价 格:¥电议型 号:T11574产 地:中国大陆
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T1152Albendazole;阿苯达唑SKF-62979;SKF-62979|||阿苯达唑
Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
价 格:¥电议型 号:T1152产 地:中国大陆
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T11494GSK3532795;化合物 T11494BMS-955176;BMS-955176
GSK3532795 is a potent, orally active, second-generation HIV-1 maturation inhibitor (EC50s: 10.2, 1.9, 2.7, and 13 nM for HIV-1 WT(human serum), HIV-1 WT, HIV-1 V370A, and HIV-1 ΔV370).
价 格:¥电议型 号:T11494产 地:中国大陆
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T11479GSK1521498;化合物 T11479GSK1521498
GSK1521498 is a selective antagonist of the μ-opioid receptor (MOR). It is being used for the treatment of disorders of compulsive consumption of food, alcohol, and drugs.
价 格:¥电议型 号:T11479产 地:中国大陆
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T11466GSK-2793660;化合物 T11466GSK-2793660
GSK-2793660 is an orally active and irreversible inhibitor of Cathepsin C (CTSC). GSK-2793660 is a bioactive dipeptide that can be used for the research of bronchiectasis [1] [2].
价 格:¥电议型 号:T11466产 地:中国大陆
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T11445GNF179 (Metabolite);化合物 T11445GNF179 Metabolite;GNF179 Metabolite
GNF179 Metabolite, the derivative of GNF179—an optimized 8,8-dimethyl IP analog—demonstrates significant potency (4.8 nM against the multidrug-resistant W2 strain) alongside in vitro metabolic stability and in vivo oral bioavailability.
价 格:¥电议型 号:T11445产 地:中国大陆