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T16448PD173212PD173212,PD-173212
PD 173212 is a blocker that blocks N-type voltage sensitive calcium channel (Cav2.2). PD173212 (0.0017-1.7 μmol/kg, Intraperitoneal Injection.) dose-dependently reduced DNBS-induced visceral hypersensitivity in mice.
价 格:¥电议型 号:T16448产 地:中国大陆
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T21617MG-115
MG-115 is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteasome, induces p53-dependent apoptosis [1] [2] [3].
价 格:¥电议型 号:T21617产 地:中国大陆
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T9638CCT241161CCT241161
CCT241161 is an orally active pan- RAF inhibitor with IC 50 s of 3, 6, 10, 15 and 30 nM for LCK, CRAF, SRC, V600E-BRAF and BRAF, respectively. CCT241161 shows good activity to in BRAF and NRAS mutant melanomas. CCT241161 also shows anticancer cell proliferative activity [1].
价 格:¥电议型 号:T9638产 地:中国大陆
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TP1672LN-Formyl-Met-Ala-Ser TFA(17351-32-5 free base)N Formyl Met Ala Ser TFA(17351 32 5 free base),NFormyl
N-Formyl-Met-Ala-Ser TFA is a peptide, binds to formyl peptide receptors on neutrophils.N-Formyl-Met-Ala-Ser Peptide (fMet-Ala-Ser) binds to formyl peptide receptors on neutrophils. N-Formylmethionine-containing peptides including the most potent and known member, N-formyl-Met-Leu-Phe (FMLP or fMet-Leu-Phe) stimulate human neutrophils by a receptor-dependent mechanism.
价 格:¥电议型 号:TP1672L产 地:中国大陆
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T16557PNU-159682inhibit,non-Hodgkin’s lymphoma,PNU159682,ADCs Toxin,PNU-159682,acute myeloid leukemia,ADC
PNU-159682 is a highly effective metabolite of the anthracycline nemorubicin. PNU-159682 has outstanding cytotoxicity. PNU-159682 is an effective ADCs cytotoxin.
价 格:¥电议型 号:T16557产 地:中国大陆
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T6337RepSoxALK5 Inhibitor II;SJN 2511;E-616452
RepSox is a potent and selective of the TGFβR-1/ALK5 inhibitor.
价 格:¥电议型 号:T6337产 地:中国大陆
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T6320GDC-0879GDC 0879;GDC0879;AR-00341677
GDC-0879 is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM with activity against c-Raf as well.
价 格:¥电议型 号:T6320产 地:中国大陆
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T6316CalcitriolCalcijex;1,25-Dihydroxyvitamin D3;Topitriol;RO215535;Rocaltrol;骨化三醇
Calcitriol is the physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (CALCIFEDIOL). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calci
价 格:¥电议型 号:T6316产 地:中国大陆
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T6249AvagacestatBMS-708163
Avagacestat (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
价 格:¥电议型 号:T6249产 地:中国大陆
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T6235Lapatinib DitosylateTykerb ditosylate;GW-572016 ditosylate;Lapatinib (GW-572016) Ditosylate;二甲苯磺酸拉帕替
Lapatinib is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).
价 格:¥电议型 号:T6235产 地:中国大陆
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T6224Iniparib3-硝基-4-碘苯甲酰胺;BSI-201;IND-71677;NSC-746045
Iniparib (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).
价 格:¥电议型 号:T6224产 地:中国大陆
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T6216Abiraterone阿比特龙;CB-7598
Abiraterone (CB-7598) is an effective steroidal cytochrome P450 17alpha-hydroxylase-17, 20-lyase (CYP17) inhibitor (IC50: 4 nM).
价 格:¥电议型 号:T6216产 地:中国大陆
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T6176IKK 16IKK Inhibitor VII;IKK16;IKK-16
IKK-16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
价 格:¥电议型 号:T6176产 地:中国大陆
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T6169Indirubin靛玉红;Indigopurpurin;NSC 105327;Couroupitine B;Indigo red
Indirubin is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM.
价 格:¥电议型 号:T6169产 地:中国大陆
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T6168ZSTK474
PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity.
价 格:¥电议型 号:T6168产 地:中国大陆
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T6167SU9516
SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.
价 格:¥电议型 号:T6167产 地:中国大陆
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T6166TelatinibBay 57-9352;替拉替尼
Telatinib is an effective inhibitor of VEGFR2/3, c-Kit, and PDGFRα. The IC50s of Telatinib forVEGFR2/3, c-Kit and PDGFRα are 6 nM/4 nM, 1 nM, and 15 nM, respectively.
价 格:¥电议型 号:T6166产 地:中国大陆
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T6165Bardoxolone MethylTP-155;NSC 713200;甲基巴多索隆;CDDO Methyl ester;RTA 402
Bardoxolone Methyl, an IKK inhibitor, exhibits effective proapoptotic and anti-inflammatory activities.
价 格:¥电议型 号:T6165产 地:中国大陆
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T6163Salirasib沙利雷塞;法尼基硫代水杨酸;FTS;Farnesyl Thiosalicylic Acid;S-Farnesylthiosalicylic acid
Salirasib(Ki=2.6 μM), an effective competitive prenylated protein methyltransferase (PPMTase) inhibitor, inhibits Ras methylation with potential antineoplastic activity.
价 格:¥电议型 号:T6163产 地:中国大陆
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T6162BS-181 hydrochlorideBS-181 HCl
BS-181 HCl is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is more than 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.
价 格:¥电议型 号:T6162产 地:中国大陆