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  • T63334Antiplatelet agent 1；化合物 Antiplatelet agent 1Antiplatelet agent 1

    Antiplatelet agent 1 is a ticagrelor analogue that exhibits anti-platelet effects and can be used in platelet agglutination studies.

    价 格：￥电议型 号：T63334产 地：中国大陆

  • T63314Antifungal agent 31；化合物 Antifungal agent 31Antifungal agent 31

    Antifungal agent 31 is an orally active, triazole antifungal agent possessing a pyrrolizinone scaffold that exhibits some antifungal activity against Candida and filamentous fungi.Antifungal agent 31 significantly reduced mortality and renal fungal burden in two mouse models of lethal systemic infection.

    价 格：￥电议型 号：T63314产 地：中国大陆

  • T63295AT2R antagonist 1；化合物 AT2R antagonist 1AT2R antagonist 1

    AT2R antagonist 1 is a highly selective and potent AT2R (angiotensin II AT2 receptor) ligand.AT2R antagonist 1 has a high affinity for AT2R affinity (Ki: 29 nM).AT2R antagonist 1 inhibits common drug metabolizing CYP enzymes and has high stability in human, rat, and mouse liver microsomes.AT2R antagonist 1 has a high affinity for AT2R affinity (Ki: 29 nM).AT2R antagonist 1 has a high affinity for AT2R affinity (Ki: 29 nM). It has high stability in human, rat and mouse liver microsomes.

    价 格：￥电议型 号：T63295产 地：中国大陆

  • T63281Antileishmanial agent-11；化合物 Antileishmanial agent-11Antileishmanial agent-11

    Antileishmanial agent-11 is a potent antileishmanial agent that acts on Leishmania brazilensis (IC50: 28.3 μM), Leishmania infantum (IC50: 24.8 μM) and T. cruzi (IC50: 13.0 μM) with outstanding antiprotozoal effect.

    价 格：￥电议型 号：T63281产 地：中国大陆

  • T63269Antibacterial agent 101；化合物 Antibacterial agent 101Antibacterial agent 101

    Antibacterial agent 101 exhibited antibacterial and antifungal effects (MIC=4-32 μg/mL).

    价 格：￥电议型 号：T63269产 地：中国大陆

  • T63208Aβ-IN-1；化合物Aβ-IN-1Aβ-IN-1

    Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM). Aβ-IN-1 potently reduced Aβ42 levels with an IC 50 value of 0.091 μM in cultured cells without inhibiting CYP3A4. Aβ-IN-1 shows a sustained pharmacokinetic profile.

    价 格：￥电议型 号：T63208产 地：中国大陆

  • T63176ALPK1-IN-1；化合物 ALPK1-IN-1ALPK1-IN-1

    ALPK1-IN-1 (Compound A001) is a potent inhibitor of alpha-kinase 1 (ALPK1). ALPK1 is an intracytoplasmic serine/threonine protein kinase that plays an important role in activating the innate immune response to bacteria by interacting with TRAF proteins of the forkhead-associated structural domain (TIFA)-dependent pro-inflammatory NF-κB signalling pathway.

    价 格：￥电议型 号：T63176产 地：中国大陆

  • T63160AD011；化合物 AD011AD011

    AD011 is a dual cACE/NEP inhibitor. AD011 was synthesized via the previously reported C-domain selective ACE inhibitor lenopril-tryptophan. AD011 shows potential to provide potent anti-hypertensive and cardioprotective effects.

    价 格：￥电议型 号：T63160产 地：中国大陆

  • T63142AChE/HDAC-IN-1；化合物 AChE/HDAC-IN-1AChE/HDAC-IN-1

    COX-2-IN-23 (compound A10) is a potent inhibitor of AChE (IC50: 0.12 nM) and HDAC (IC50: 0.23 nM).COX-2-IN-23 exhibits antioxidant and metal chelating properties.COX-2-IN-23 can be used to study Alzheimer´s disease.

    价 格：￥电议型 号：T63142产 地：中国大陆

  • T63075ALOX15-IN-1；化合物 ALOX15-IN-1ALOX15-IN-1

    ALOX15-IN-1 (compound 8b) is a selective and potent inhibitor of rabbit and human ALOX15 linoleate oxygenase activity, acting on the direct homologues of ALOX15 linoleic acid (LA) (IC50: 0.04 μM) and arachidonic acid (AA) (IC50. 2.06 μM).

    价 格：￥电议型 号：T63075产 地：中国大陆

  • T62945Aurora A/PKC-IN-1；化合物 Aurora A/PKC-IN-1Aurora A/PKC-IN-1

    Aurora A/PKC-IN-1 (Compound 2e) is a potent dual inhibitor of Aurora A (AurA) and PKC (α, β1, β2, θ), acting on AurA (IC50: 6.9 nM) and PKCα (IC50: 16.9 nM). Aurora A/PKC-IN-1 showed anti-proliferative and anti-metastatic effects on breast cancer cells.

    价 格：￥电议型 号：T62945产 地：中国大陆

  • T628435-HT1A antagonist 1；化合物 5-HT1A?antagonist 15-HT1A antagonist 1

    5-HT1A antagonist 1 (compound 6f) is a potent and selective 5-HT1Areceptor antagonist (Ki: 35 nM). 5-HT1A antagonist 1 can be used in the study of central nervous system disorders.

    价 格：￥电议型 号：T62843产 地：中国大陆

  • T62719AChE/BACE1/GSK3β-IN-1；化合物 AChE/BACE1/GSK3β-IN-1AChE/BACE1/GSK3β-IN-1

    AChE/BACE1/GSK3β-IN-1 is an orally active, blood-brain barrier-transparent, moderately bioavailable triple inhibitor of AChE/BACE1/GSK3β. AChE/BACE1/GSK3β-IN-1 can be used to study Alzheimer´s disease (AD).

    价 格：￥电议型 号：T62719产 地：中国大陆

  • T62667Anticancer agent 51；化合物 Anticancer agent 51Anticancer agent 51

    Anticancer agent 51 (compound 3d) is a potent anticancer agent (Ki: 731.62 nM) with anticancer activity. anticancer agent 51 has potential for prostate cancer research.

    价 格：￥电议型 号：T62667产 地：中国大陆

  • T62651ATR-IN-11；化合物 ATR-IN-11ATR-IN-11

    ATR-IN-11 (Compound Hit01) is a potent inhibitor of ataxia capillaris and Rad3-related (ATR) kinases. ATR-IN-11 is a promising lead compound for the discovery of subsequent drugs targeting the ATR kinase, a key regulatory protein in the DNA damage response (DDR) responsible for sensing replication stress (RS). ATR-IN-11 has potential for cancer disease research.

    价 格：￥电议型 号：T62651产 地：中国大陆

  • T62575Anti-ToCV agent 1；化合物 Anti-ToCV agent 1Anti-ToCV agent 1

    Anti-ToCV agent 1 can be used as a potential anti-ToCV drug.

    价 格：￥电议型 号：T62575产 地：中国大陆

  • T6257AZ191；化合物AZ191AZ191

    AZ191（IC50 of 17 nM） is an effective and specific DYRK1B inhibitor. The specificity of AZ191 for DYRK1B is about 5- and 110-fold greater over DYRK1A and DYRK2, respectively.

    价 格：￥电议型 号：T6257产 地：中国大陆

  • T62551ANEB-001；化合物 ANEB-001ANEB-001

    ANEB-001 is an orally active CB1 inhibitor that can be used in studies of acute cannabinoid intoxication.

    价 格：￥电议型 号：T62551产 地：中国大陆

  • T62521A2AAR/HDAC-IN-1；化合物 A2AAR/HDAC-IN-1A2AAR/HDAC-IN-1

    A2AAR/HDAC-IN-1 (compound 14c) is an orally active, balanced A2AAR/HDAC dual inhibitor of A2AAR (Ki: 163.5 nM), HDAC1 (IC50: 145.3 nM). effect.

    价 格：￥电议型 号：T62521产 地：中国大陆

  • T62511AZ3391；化合物 AZ3391AZ3391

    AZ3391 is a quinoxaline derivative that is a potent inhibitor of PARP. AZ3391 has potential for the study of diseases and conditions occurring in central nervous system tissues (e.g., brain and spinal cord).

    价 格：￥电议型 号：T62511产 地：中国大陆

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