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T4365FL-411FL411;FL 411;BRD4-IN-1
FL-411 is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4.
价 格:¥电议型 号:T4365产 地:中国大陆
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T4364Aftin-4Aftin4;Aftin 4
Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor. Aftin-4 increased Aβ-1-42, but not Aβ-1-40 in mouse hipppocampus, accompanied by learning deficits and mito
价 格:¥电议型 号:T4364产 地:中国大陆
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T4362WM-8014MOZ-IN-3
MOZ-IN-3 is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.
价 格:¥电议型 号:T4362产 地:中国大陆
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T4361CBL0137 hydrochlorideCBLC137;CBL0137;Curaxin-137 hydrochloride;CBL-C137 hydrochloride;Curaxin 137
CBL0137 activates p53 and inhibits NF-kB (EC50: 0.37/0.47 μM) in the cell-based p53 and NF-kB reporter assays, respectively. It also suppresses histone chaperone FACT.
价 格:¥电议型 号:T4361产 地:中国大陆
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T4354KPT9274KPT 9274;PAK4-IN-1;KPT-9274
KPT-9274 is a non-competitive dual inhibitor of PAK4 and NAMPT(IC50= ~120 nM). It is an orally bioavailable small molecule.
价 格:¥电议型 号:T4354产 地:中国大陆
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T4353SR-18292SR 18292;SR18292
SR-18292 is a PPAR gamma coactivator-1α (PGC-1α) inhibitor, which increases PGC-1α acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes.
价 格:¥电议型 号:T4353产 地:中国大陆
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T4351DAMGODagol;DAGO;RX-783006
DAMGO is an opioid receptor agonist with the ability to affect the locomotive activity in rodents. Possible analgesic agent due to μ-opiod receptor interaction.
价 格:¥电议型 号:T4351产 地:中国大陆
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T4350PalifosfamideIsophosphamide mustard;ZIO-201;Isophosphoramide mustard;帕利伐米
Palifosfamide lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to 6.75 μM for most cell lines except OS222 (IC50=31.5 μM).
价 格:¥电议型 号:T4350产 地:中国大陆
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T4349SitravatinibMG516;MGCD516
Sitravatinib (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and Axl.
价 格:¥电议型 号:T4349产 地:中国大陆
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T4348Syk Inhibitor II
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
价 格:¥电议型 号:T4348产 地:中国大陆
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T4347ML355
ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.
价 格:¥电议型 号:T4347产 地:中国大陆
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T4346SPDB
SPDB is a small fragment linked to DM4 conjugates. It conjugates to antibodies utilizing disulfide linkers: anti-EGFR-SPDB-DM4 has been widely used.
价 格:¥电议型 号:T4346产 地:中国大陆
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T4345CeMMEC1CeMMEC1 HCl
CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).
价 格:¥电议型 号:T4345产 地:中国大陆
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T4344ALW-II-41-27Eph receptor tyrosine kinase inhibitor
ALW-II-41-27, an Eph receptor tyrosine kinase inhibitor, is used for cancer therapy.
价 格:¥电议型 号:T4344产 地:中国大陆
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T4343A-196A196;A 196
A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective over other histone methyltransferases and non-epigenetic targets.
价 格:¥电议型 号:T4343产 地:中国大陆
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T4342PF-04929113 MesylatePF-04929113 (Mesylate);SNX-5422 Mesylate
PF-04929113 Mesylate, a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37 nM).
价 格:¥电议型 号:T4342产 地:中国大陆
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T4340SPI-112SPI 112
SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2.
价 格:¥电议型 号:T4340产 地:中国大陆