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T3763Fumaric acidDonitic acid；2-Butenedioic acid；Trans-Butenedioic acid；Fumarate；Allomaleic acid；Lichenic
Fumaric acid attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as an oncometabolite or an endogenous, cancer-causing metabolite. High levels of
价 格：￥电议型 号：T3763产 地：中国大陆
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T3730Methyl gallate没食子酸甲酯；Gallic acid methyl ester；Gallincin；Gallicin；NSC 363001
Methyl gallate is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.
价 格：￥电议型 号：T3730产 地：中国大陆
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T3703ABT-639ABT 639；ABT639
ABT-639 is a potent and selective T-type calcium channel blocker.
价 格：￥电议型 号：T3703产 地：中国大陆
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T36670JNJ-67856633
JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric MALT1 protease inhibitor. JNJ-67856633 in some cases lead to tumor stasis[1][2][3].
价 格：￥电议型 号：T36670产 地：中国大陆
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T36631BAY-6035
BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). It is 100-fold selective for SMYD3 over other histone methyltransferases. BAY-6035 inhibits methylation of MEKK2 peptide in a cell-free assay and in cells (IC50s = 88 and 70 nM,
价 格：￥电议型 号：T36631产 地：中国大陆
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T3663Eliglustat依利格鲁司特；GENZ-112638；Genz 99067
Eliglustat is an oral inhibitor of glucosylceramide synthase which is used in the therapy of type 1 Gaucher disease.
价 格：￥电议型 号：T3663产 地：中国大陆
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T3644U93631
GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GABA-induced Cl- currents with little effect on peak amplitude. Also inhibits 5-HT3A receptors vi
价 格：￥电议型 号：T3644产 地：中国大陆
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T3639A-804598A 804598；A804598
A-804598 is a competitive and selective P2X7 receptor antagonist (IC50: 10 nM, rat; 9 nM, mouse; 11 nM, human).
价 格：￥电议型 号：T3639产 地：中国大陆
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T3638Leukadherin-1
Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendothelial migration; reduces inflammation.
价 格：￥电议型 号：T3638产 地：中国大陆
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T3637Pifithrin-β hydrobromidePifithrin-β；Cyclic PFT-α；PFT-β；Cyclic Pifithrin-α hydrobromide；PFT β (hydrob
Pifithrin-β hydrobromide is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-eff
价 格：￥电议型 号：T3637产 地：中国大陆
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T3636(E)-SIS3SIS3 盐酸盐；SIS3；SIS3 HCl
SIS3, a selective Smad3 inhibitor, can attenuate TGF-β1-dependent Smad3 phosphorylation and DNA binding. It has no effect on p38 MAPK, Smad2, ERK or PI3K signaling. It also inhibits TGF-β1-induced myofibroblast differentiation of dermal fibroblasts and in
价 格：￥电议型 号：T3636产 地：中国大陆
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T3635IQ 1IQ-1；IQ1
Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells; enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation. Upregulates expression of Oct4 and Sox2 transcription factors. Binds to serine/threonin
价 格：￥电议型 号：T3635产 地：中国大陆
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T3634Osimertinib mesylate甲磺酸奥希替尼；奥希替尼甲磺酸盐；Mereletinib mesylate；AZD-9291 mesylate
Osimertinib (AZD-9291) is an irreversible and mutant selective EGFR inhibitor (IC50s: 12/1 nM for EGFR(L858R) and EGFR(L858R/T790M)).
价 格：￥电议型 号：T3634产 地：中国大陆
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T3633CrenigacestatLY3039478
LY3039478 is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested. LY3039478 effectively inhibits mutant Notch receptor activity. In a xenograft tumor model, LY3039478 inhibited expression of Notch-regulated
价 格：￥电议型 号：T3633产 地：中国大陆
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T3632DoravirineMK-1439；多拉维林；多拉韦林
Doravirine is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.
价 格：￥电议型 号：T3632产 地：中国大陆
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T3631PF-8380PF8380；PF 8380
PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood). It modulates lysophosphatidic acid (LPA) levels in vivo/vitro by directly inhibiting autotaxin; reduces LPA levels
价 格：￥电议型 号：T3631产 地：中国大陆
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T3630RelugolixRVT-601；TAK-385；瑞卢戈利
Relugolix is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively binds to and blocks the GnRH receptor in the an
价 格：￥电议型 号：T3630产 地：中国大陆
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T3558EBE-A22PD153035 Analog 63
EBE-A22 is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.
价 格：￥电议型 号：T3558产 地：中国大陆
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T353635-Hydroxymethylcytosine5hmC；5-Hydroxymethylcytosine
5-Hydroxymethylcytosine is a naturally occurring component of mammalian genomic DNA and is thought to be the sixth base of DNA [1]. 5-Hydroxymethylcytosine is an intermediate metabolite for demethylation of active DNA [2]. 5-Hydroxymethylcytosine is an ep
价 格：￥电议型 号：T35363产 地：中国大陆
