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T11413Glucagon receptor antagonists-1；化合物 T11413Glucagon receptor antagonists-1
Glucagon receptor antagonist -1 is a highly effective glucagon receptor antagonist.
价 格：￥电议型 号：T11413产 地：中国大陆
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T11350GABAB receptor antagonist 1；化合物 T11350GABAB receptor antagonist 1
(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors.
价 格：￥电议型 号：T11350产 地：中国大陆
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T11237Camizestrant；化合物CamizestrantEstrogen receptor antagonist 2；Estrogen receptor antagonist 2
Camizestrant (Estrogen receptor antagonist 2) is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1].
价 格：￥电议型 号：T11237产 地：中国大陆
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T11236Giredestrant tartrate；Giredestrant酒石酸盐Estrogen receptor antagonist 1；Estrogen receptor antagonist 1
Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, resulting in the failure of ER to activate the transcription of targeted genes and promoting the degradation of ER protein. Giredestrant tartrate can be used to treat tumor diseases.
价 格：￥电议型 号：T11236产 地：中国大陆
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T11230ERRα antagonist-1；化合物ERRα 拮抗剂-1ERR+/- antagonist-1|||ERRa antagonist-1；ERR+/- antagonist-1|||ERRa an
ERRα antagonist-1 (ERR+/- antagonist-1) is a high-affinity, selective antagonist of the estrogen-related receptor α (ERRα). It effectively prevents the interaction of ERRα with both Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, displaying IC50 values of 170 nM and 180 nM, respectively. Notably, ERRα antagonist-1 does not interfere with the interactions involving ERRβ or ERRγ and the PGC-1α and PGC-1β coactivators. Furthermore, it does not affect the interaction between ei
价 格：￥电议型 号：T11230产 地：中国大陆
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T11211EP4 receptor antagonist 1；化合物EP4 receptor antagonist 1EP4 receptor antagonist 1
EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and 16.2 nM, respectively, while displaying minimal activity (IC50s >10 μM) against human EP1, EP2, and EP3 receptors.
价 格：￥电议型 号：T11211产 地：中国大陆
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T11137(E)-GABAB receptor antagonist 1；(E)-GABAB受体拮抗剂-1(E)-GABAB receptor antagonist 1
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors.
价 格：￥电议型 号：T11137产 地：中国大陆
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T11077Dopamine D2 receptor antagonist-1；多巴胺D2受体拮抗剂-1Dopamine D2 receptor antagonist-1
Dopamine D2 Receptor Antagonist-1 functions as a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R), demonstrating sub-millimolar affinity.
价 格：￥电议型 号：T11077产 地：中国大陆
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T10911H3 receptor antagonist 1；化合物 T10911H3 receptor antagonist 1
H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist.
价 格：￥电议型 号：T10911产 地：中国大陆
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T10889CRTh2 antagonist 2；CRTh2拮抗剂2CRTh2 antagonist 2
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
价 格：￥电议型 号：T10889产 地：中国大陆
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T10714CCR5 antagonist 1；化合物 T10714CCR5 antagonist 1
CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.
价 格：￥电议型 号：T10714产 地：中国大陆
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T10713CCR4 antagonist 2；化合物 T10713CCR4 antagonist 2
CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. CCR4 antagonist 2 (Compound 31) exhibits IC50 values of Ca2+flux and (chemotaxis) CTX are 40 nM and 70 nM, respectively.
价 格：￥电议型 号：T10713产 地：中国大陆
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T10712CCR2 antagonist 3；化合物CCR2 antagonist 3AZD-2927|||AZD2927；AZD-2927|||AZD2927
CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.
价 格：￥电议型 号：T10712产 地：中国大陆
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T10711CCR2 antagonist 1；化合物 T10711CCR2 antagonist 1
CCR2 antagonist 1 is a high-affinity and long-residence-time antagonist of CCR2 (Ki: 2.4 nM).
价 格：￥电议型 号：T10711产 地：中国大陆
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T10710CCR1 antagonist 9；化合物 T10710CCR1 antagonist 9
CCR1 antagonist 9 is an effective and selective CCR1 antagonist (IC50: 6.8 nM in calcium flux assay).
价 格：￥电议型 号：T10710产 地：中国大陆
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T10709CCR1 antagonist 7；化合物 T10709CCR1 antagonist 7
CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].
价 格：￥电议型 号：T10709产 地：中国大陆
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T10708CCR1 antagonist 6；CCR1拮抗剂6CCR1 antagonist 6
CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).
价 格：￥电议型 号：T10708产 地：中国大陆
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T10707CCK-B Receptor Antagonist 2；化合物 T10707CCK-B Receptor Antagonist 2
CCK-B Receptor Antagonist 2 is a potent and orally active antagonist of Gastrin/CCK-B (IC50: 0.43 nM). It also inhibits gastrin/CCK-A activity (IC50: 1.82 μM).
价 格：￥电议型 号：T10707产 地：中国大陆
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T10665Calcium-Sensing Receptor Antagonists I；化合物 T10665Calcium-Sensing Receptor Antagonists I
Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.
价 格：￥电议型 号：T10665产 地：中国大陆
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T10560P2X3 antagonist 34；化合物 T10560BLU-5937；BLU-5937
P2X3 antagonist 34, a potent, selective, and orally active antagonist, targets the P2X3 homotrimeric receptor, exhibiting IC50s of 25 nM, 92 nM, and 126 nM for human, rat, and guinea pig P2X3 receptors respectively. It shows reduced activity against P2X2/3 heterotrimeric receptors across human, rat, and guinea pig models. Notably, this compound demonstrates a significant anti-tussive effect without altering taste[1].
价 格：￥电议型 号：T10560产 地：中国大陆
