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T10466BAY-1797；化合物BAY-1797BAY-1797
BAY-1797 is an orally active and selective P2X4 antagonist (IC50: 211 nM against human P2X4) with anti-nociceptive and anti-inflammatory effects. BAY-1797 displays no or very weak activity on the other P2X ion channels.
价 格：￥电议型 号：T10466产 地：中国大陆
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T10465Atuveciclib S-Enantiomer；化合物 T10465BAY-1143572 S-Enantiomer；BAY-1143572 S-Enantiomer
Atuveciclib S-Enantiomer (BAY-1143572 S-Enantiomer) is the (S)-enantiomer of BAY-1143572. Atuveciclib S-Enantiomer is a potent and selective CDK9 inhibitor, which inhibits CDK9 / CycT1 with an IC 50 of 16 nM.
价 格：￥电议型 号：T10465产 地：中国大陆
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T10464LAtuveciclib Racemate；阿维西利BAY-1143572 Racemate；BAY-1143572 Racemate|||阿维西利
Atuveciclib Racemate (BAY-1143572 Racemate) is the racemate mixture of Atuveciclib, which is a potent and highly selective, oral P-TEFb/CDK9 inhibitor which supresses CDK9/CycT1 with an IC50 of 13 nM.
价 格：￥电议型 号：T10464L产 地：中国大陆
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T10464Atuveciclib；化合物 T10464BAY-1143572；BAY-1143572
Atuveciclib (BAY-1143572) is a potent and highly selective, oral PTEFb / CDK9 inhibitor that inhibits CDK9 / CycT1 with an IC 50 of 13 nM [1].
价 格：￥电议型 号：T10464产 地：中国大陆
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T10463LBax inhibitor peptide V5 acetate；化合物T10463LBax inhibitor peptide V5 acetate（579492-81-2 free base)；B
Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate（579492-81-2 free base)) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.
价 格：￥电议型 号：T10463L产 地：中国大陆
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T10462LBavisant dihydrochloride hydrate；化合物 T10462LJNJ31001074AAC；JNJ31001074AAC
Bavisant dihydrochloride hydrate (JNJ31001074AAC) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. in vivo: Mean change from baseline in the total ADHD-RS-IV score at day 42 (primary efficacy endpoint) was -8.8 in the placebo group versus -9.3, -11.2 and -12.2 in the bavisant 1 mg/day, 3 mg/day and 10 mg/day groups, respectively; the change in the 10 mg/day group
价 格：￥电议型 号：T10462L产 地：中国大陆
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T10460Batabulin；巴他布林T138067；巴他布林|||T138067
Batabulin (T138067) is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization. Batabulin affects cell morphology and leads to cell-cycle arrest ultimately induce apoptotic cell death.
价 格：￥电议型 号：T10460产 地：中国大陆
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T1046Mexiletine hydrochloride；盐酸美西律KOE-1173 (hydrochloride)|||Mexiletine HCl|||KO1173；KOE-1173 (hydrochlo
Mexiletine hydrochloride (KOE-1173 hydrochloride) is a voltage-gated sodium channel blocker and a Class IB antiarrhythmic drug. Mexiletine hydrochloride exerts antiarrhythmic effects by inhibiting sodium current in myocardial cells, thereby reducing the rise rate of cardiac action potential (phase 0) and reducing the automaticity of Purkinje fibers.
价 格：￥电议型 号：T1046产 地：中国大陆
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T10457BAN ORL 24；化合物 T10457BAN ORL 24
BAN ORL 24 is a potent and selective NOP receptor antagonist (IC50s: 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors).
价 格：￥电议型 号：T10457产 地：中国大陆
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T10447BAA473；化合物 T10447BAA473
BAA473 is a bile acid analog that is a potent activator of the pyrin inflammasome. BAA473 can induce secretion of interleukin-18 (IL-18) through activation of the inflammasome in both myeloid and intestinal epithelial cells [1].
价 格：￥电议型 号：T10447产 地：中国大陆
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T10439Azelnidipine D7；化合物 T10439CS-905 D7；CS-905 D7
Azelnidipine D7 is a deuterium-labeled Azelnidipine. Azelnidipine is an L-type calcium channel blocker.
价 格：￥电议型 号：T10439产 地：中国大陆
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T10438AZD 4407；化合物 T10438ZD 4407；ZD 4407
AZD 4407 is a potent inhibitor of 5-lipoxygenase.
价 格：￥电议型 号：T10438产 地：中国大陆
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T10437AZD8848；化合物 T10437AZD8848
AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.
价 格：￥电议型 号：T10437产 地：中国大陆
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T10436LAZD4573 HCl (2057509-72-3 free base)；化合物 T10436LAZD4573 hydrochloride|||AZD4573|||AZD4573 HCl|||AZD-
AZD-4573 is a selective and short-acting inhibitor of the serine/threonine cyclin-dependent kinase 9, the catalytic subunit of the RNA polymerase II elongation factor positive transcription elongation factor b. It also has a potential antineoplastic activity.
价 格：￥电议型 号：T10436L产 地：中国大陆
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T10436AZD4573；化合物AZD4573AZD4573
AZD4573 is an effective and selective CDK9 inhibitor (IC50: <4 nM). It enables transient target engagement for the treatment of hematologic malignancies.
价 格：￥电议型 号：T10436产 地：中国大陆
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T10427AZ505 ditrifluoroacetate；化合物 T10427AZ505 ditrifluoroacetate
AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).
价 格：￥电议型 号：T10427产 地：中国大陆
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T10417Autotaxin-IN-5；化合物 T10417Autotaxin-IN-5
Autotaxin-IN-5 is an Autotaxin inhibitor. It has the potential to treat idiopathic pulmonary fibrosis.
价 格：￥电议型 号：T10417产 地：中国大陆
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T10407Gartisertib；化合物 T10407ATR inhibitor 2；ATR inhibitor 2
ATR inhibitor 2 is an orally active, ATP-competitive, and selective ATR inhibitor (Ki <150 pM) with antitumor activity. ATR inhibitor 2 potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylation (IC50: 8 nM).
价 格：￥电议型 号：T10407产 地：中国大陆
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T10406Tuvusertib；化合物TuvusertibM1774|||ATR inhibitor 1；M1774|||ATR inhibitor 1
Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 ?Μ) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks downstream phosphorylation of serine/threonine protein kinase checkpoint kinase 1 (CHK1), thereby inhibits DNA damage checkpoint activation, disrupting DNA damage repair and inducing apoptosis in tumor cells.
价 格：￥电议型 号：T10406产 地：中国大陆
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T10397ATN-161 trifluoroacetate salt；化合物ATN-161 trifluoroacetate saltATN-161 TFA salt；ATN-161 TFA salt
ATN-161 trifluoroacetate salt (ATN-161 TFA salt) is a novel integrin α5β1 antagonist that inhibits angiogenesis and growth of liver metastases and improves survival in a murine model.
价 格：￥电议型 号：T10397产 地：中国大陆
