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T1836AZD2932；化合物AZD2932AZD2932
AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.
价 格：￥电议型 号：T1836产 地：中国大陆
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T18329MC-VC(S)-PABQ-Tubulysin M；化合物 T18329MC-Val-Cit-PAB-tubulysin5a；MC-Val-Cit-PAB-tubulysin5a
MC-Val-Cit-PAB-tubulysin5a is a drug-linker conjugate for ADC with potent antitumor activity by using tubulysin5a (a tubulin inhibitor), linked via the ADC linker MC-Val-Cit-PAB.
价 格：￥电议型 号：T18329产 地：中国大陆
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T18299Mal-PEG8-Val-Cit-PAB-MMAE；化合物 T18299MalPEG8ValCitPABMMAE|||Mal PEG8 Val Cit PAB MMAE|||Mal-PEG-8-Val
Mal-PEG8-Val-Cit-PAB-MMAE is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T18299产 地：中国大陆
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T18298Mal-PEG8-alcohol；化合物 T18298Mal-PEG8-alcohol
Mal-PEG8-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18298产 地：中国大陆
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T18297Mal-PEG6-mal；化合物 T18297Mal-PEG6-mal
Mal-PEG6-mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18297产 地：中国大陆
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T18296Mal-PEG5-mal；化合物 T18296Mal-PEG5-mal
Mal-PEG5-mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18296产 地：中国大陆
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T18295Mal-PEG5-Boc化合物Mal-PEG5-BocMal-PEG5-COOtBu|||Mal-PEG5-T-Butyl Ester
Mal-PEG5-Boc (Mal-PEG5-COOtBu) is a PEG-based PROTAC linker. Mal-PEG5-Boc can be used in the synthesis of PROTACs.
价 格：￥电议型 号：T18295产 地：中国大陆
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T18294Mal-PEG4-VC-PAB-DMEA；化合物 T18294Mal-PEG4-VC-PAB-DMEA|||MalPEG4VCPABDMEA|||Mal PEG4 VC PAB DMEA|||Mal-
Mal-PEG4-VC-PAB-DMEA is a cleavable ADC linker that incorporates a Maleimide moiety. It is employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T18294产 地：中国大陆
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T18293Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA；化合物 T18293Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA
Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is an antibody-drug conjugate linker that incorporates the antitumor antibiotic Duocarmycin SA, connected through the Mal-PEG4-VC-PAB-DMEA-Seco linker, for targeted cancer therapy.
价 格：￥电议型 号：T18293产 地：中国大陆
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T18292Mal-PEG4-VC-PAB-DMEA-PNU-159682；化合物 T18292Mal-PEG4-VC-PAB-DMEA-PNU159682|||MalPEG4VCPABDMEAPNU159682
Mal-PEG4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) therapy. It combines the ADC linker, Mal-PEG4-VC-PAB, with the potent ADC cytotoxin, DMEA-PNU-159682. The cytotoxin, DMEA-PNU-159682, is derived from metabolites of nemorubicin (MMDX) found in liver microsomes, as well as the ADC cytotoxin PNU-159682[1].
价 格：￥电议型 号：T18292产 地：中国大陆
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T18291Mal-PEG4-Val-Cit-PAB；化合物 T18291Mal-PEG4-Val-Cit-PAB
Mal-PEG4-Val-Cit-PAB, a cleavable ADC linker incorporating a Maleimide moiety, finds application in the construction of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T18291产 地：中国大陆
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T18290Mal-PEG4-VA；化合物 T18290Mal-PEG4-VA
Mal-PEG4-VA, a noncleavable ADC linker featuring a Maleimide group, is utilized in the synthesis of antibody-drug conjugates.
价 格：￥电议型 号：T18290产 地：中国大陆
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T1829Ruxolitinib芦可替尼芦可替尼|||INCB018424|||鲁索替尼|||(R)-Ruxolitinib
Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.
价 格：￥电议型 号：T1829产 地：中国大陆
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T18229m-PEG9-SH；化合物m-PEG9-SHm-PEG9-SH
m-PEG9-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18229产 地：中国大陆
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T18029HS-PEG7-CH2CH2NH2；化合物 T18029Thiol-PEG7-amine；Thiol-PEG7-amine
HS-PEG7-CH2CH2NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18029产 地：中国大陆
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T1793MBX-2982；化合物MBX2982MBX-2982
MBX-2982 is a selective, orally-available GPR119 agonist, used for the treatment of diabetes.
价 格：￥电议型 号：T1793产 地：中国大陆
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T17929EC089；化合物 T17929EC089
EC089 is a cleavable linker employed in tubulysins and folates conjugates[1].
价 格：￥电议型 号：T17929产 地：中国大陆
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T1790Fosaprepitant dimeglumine；福沙吡坦二甲葡胺L785298|||MK-0517|||Fosaprepitant dimeglumine salt；福沙匹坦二甲葡胺|||L785
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis.
价 格：￥电议型 号：T1790产 地：中国大陆
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T17829Diketone-PEG4-PFP ester；化合物 T17829Diketone-PEG4-PFP ester
Diketone-PEG4-PFP ester is a polyethylene glycol (PEG) derivative employed as a PROTAC linker in the fabrication of proteolysis-targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T17829产 地：中国大陆
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T1776Plerixafor；普乐沙福JM3100|||AMD 3100|||AMD-3329；普乐沙福|||JM3100|||AMD 3100|||AMD-3329
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.
价 格：￥电议型 号：T1776产 地：中国大陆
