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T17363β-Naphthoflavone-CH2-OH；化合物 T17363β-NF-CH2-OH；β-NF-CH2-OH
β-Naphthoflavone-CH2-OH (β-NF-CH2-OH) serves as an AhR E3 ligase ligand, forming chimeric molecules when connected to a protein ligand through a linker, resulting in PROTACs or SNIPERs (e.g., β-naphthoflavone-JQ1). These chimeric molecules recruit the AhR E3 ligase complex by incorporating AhR ligands. By inducing ubiquitination-mediated degradation, PROTACs effectively target and degrade cancer-promoting proteins [1].
价 格：￥电议型 号：T17363产 地：中国大陆
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T17362Acrylate-PEG-OH (MW 5000)；化合物 T17362Acrylate-PEG-OH (MW 5000)
Acrylate-PEG-OH (MW 5000) is a Polyethylene Glycol (PEG)-based linker compound primarily utilized in PROTAC synthesis[1].
价 格：￥电议型 号：T17362产 地：中国大陆
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T17361Acrylate-PEG-OH (MW 3400)；化合物 T17361Acrylate-PEG-OH (MW 3400)
Acrylate-PEG-OH (MW 3400) is a polyethylene glycol (PEG) derived PROTAC linker compound, which finds application in the synthesis of PROTACs[1].
价 格：￥电议型 号：T17361产 地：中国大陆
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T17360Acrylate-PEG-OH (MW 10000)；化合物 T17360Acrylate-PEG-OH (MW 10000)
Acrylate-PEG-OH (MW 10000) is a Polyethylene Glycol (PEG) derived PROTAC linker utilized for synthesizing PROTACs[1].
价 格：￥电议型 号：T17360产 地：中国大陆
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T1736Apixaban阿哌沙班阿哌沙班|||BMS-562247-01
Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and preventing the formation of cross-linked fibrin clots.
价 格：￥电议型 号：T1736产 地：中国大陆
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T173364-(N-Boc-amino)-1,6-heptanedioic acid；化合物 T173364-(N-Boc-amino)-1,6-heptanedioic acid
4-(N-Boc-amino)-1,6-heptanedioic acid is an alkyl/ether-based linker, suitable for PROTAC synthesis [1].
价 格：￥电议型 号：T17336产 地：中国大陆
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T17236Volixibat；化合物 T17236SHP626|||LUM002；SHP626|||LUM002
Volixibat is a highly selective and competitive apical sodium-dependent bile acid transporter inhibitor. Volixibat has the potential for treatment for non-alcoholic steatohepatitis.
价 格：￥电议型 号：T17236产 地：中国大陆
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T17222Velneperit；韦利贝特S2367；韦利贝特|||S2367
Velneperit (S2367) is potent and selective neuropeptide Y (NPY) Y5 receptor under evaluating for treatment of obesity.
价 格：￥电议型 号：T17222产 地：中国大陆
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T17210L1(3R,6R)-Vaborbactam(3R,6R)-法硼巴坦(3R,6R)-RPX7009|||(3R,6R)-Vaborbactam (Iso-1360457-46-0)
(3R,6R)-Vaborbactam ((3R,6R)-Vaborbactam (Iso-1360457-46-0)) is a cyclic boronic acid pharmacophore β-lactamase inhibitor with potential antimicrobial activity. (S)-Vamicamide ((S)-Vamicamide (Iso-132373-81-0)) is a novel anticholinergic compound.
价 格：￥电议型 号：T17210L1产 地：中国大陆
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T17210LVaborbactam ammonium salt；法硼巴坦铵盐RPX7009 ammonium salt|||Vaborbactam ammonium salt（1360457-46-0 Free
Vaborbactam ammonium salt is a β-lactamase inhibitor that restores carbapenem activity against KPC-producing strains and is often used in conjunction with other drugs to study fungal infections.
价 格：￥电议型 号：T17210L产 地：中国大陆
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T17181TVB-3664；化合物TVB-3664TVB-3664
TVB-3664 significantly decreases tubulin palmitoylation and mRNA expression. TVB-3664 is a reversible and highly bioavailable fatty acid synthase inhibitor (IC50: 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively).
价 格：￥电议型 号：T17181产 地：中国大陆
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T17136Tos-PEG6-C2-Boc；化合物 T17136Tos-PEG6-C2-Boc
Tos-PEG6-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17136产 地：中国大陆
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T17071Thiarabine；化合物 T17071OSI-7836；OSI-7836
Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.
价 格：￥电议型 号：T17071产 地：中国大陆
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T17036Tenidap；替尼达普CP-66248；CP-66248
Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.
价 格：￥电议型 号：T17036产 地：中国大陆
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T17021Tebipenem；泰比培南LJC 11036；LJC 11036
Tebipenem is an orally available carbapenem antibiotic. It displays broad-spectrum activity against Gram-positive and -negative bacteria.
价 格：￥电议型 号：T17021产 地：中国大陆
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T16936SS-208；化合物SS-208SS-208
SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.
价 格：￥电议型 号：T16936产 地：中国大陆
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T16890SJG-136；化合物 T16890NSC-694501；NSC-694501
SJG-136 is a DNA cross-linking agent (XL50: 45 nM for pBR322 DNA).
价 格：￥电议型 号：T16890产 地：中国大陆
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T16878SHP836；化合物 T16878SHP836
SHP836 is an inhibitor of SHP2 allosteric (IC50: 12 μM for the full-length SHP2).
价 格：￥电议型 号：T16878产 地：中国大陆
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T16836SAFit2；化合物SAFit2SAFit2
SAFit2 is a highly effective and selective fk506 binding protein 51(FKBP51) inhibitor (Ki: 6 nM). SAFit2 can enhance AKT2-AS160 binding and participate in the downstream response of glucocorticoid release in vivo, and is a candidate compound for the treatment of obesity, chronic pain, depression and anxiety.
价 格：￥电议型 号：T16836产 地：中国大陆
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T16813RX-3117；化合物RX-3117fluorocyclopentenylcytosine|||TV-1360；fluorocyclopentenylcytosine|||TV-1360
RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog. RX-3117 displays anticancer activity in several cancer cell lines, including gemcitabine-resistant variants.
价 格：￥电议型 号：T16813产 地：中国大陆
