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产品数：86101
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T11476GSK-J2；化合物 T11476GSK-J2
GSK-J2, an isomer of GSK-J1, haven´t any specific activity. GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.
价 格：￥电议型 号：T11476产 地：中国大陆
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T11472LMolibresib besylate化合物 T11472LI-BET 762 besylate|||GSK 525762C
Molibresib besylate is an inhibitor of BET bromodomain (IC50: 32.5-42.5 nM).
价 格：￥电议型 号：T11472L产 地：中国大陆
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T11472GSK 525768A；化合物 T11472GSK 525768A
GSK 525768A, the inactive enantiomer of GSK525762A, exhibits no activity towards BET.
价 格：￥电议型 号：T11472产 地：中国大陆
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T11402LGKI-1 HCl；GKI-1盐酸盐GKI-1 HCl（ 2444764-03-6 Free base）；GKI-1 HCl（ 2444764-03-6 Free base）
GKI-1 HCl is a Greatwall (GWL) kinase inhibitor that inhibits hGWLFL and hGWL-KinDom.The inhibitory effect of GKI-1 HCl on ROCK1 is more significant.
价 格：￥电议型 号：T11402L产 地：中国大陆
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T11377GDC-0276；化合物 T11377GDC-0276
GDC-0276, a potent, selective, reversible, and orally active NaV1.7 inhibitor with an IC50 value of 0.4 nM, offers potential for pain treatment while overcoming limitations associated with current pain medications, including addiction and off-target side effects. It is well tolerated and demonstrates a favorable pharmacokinetic profile.
价 格：￥电议型 号：T11377产 地：中国大陆
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T11376GC 14；化合物 T11376GC 14
GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 200 nM and 35 nM for hTRα and hTRβ, respectively.
价 格：￥电议型 号：T11376产 地：中国大陆
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T11331LFTI 276；化合物 T11331LFTI 276
FTI-276 is an inhibitor of protein farnesyltransferase (PFT) (IC50s: 0.9 and 0.5 nM for Plasmodium falciparum and human).
价 格：￥电议型 号：T11331L产 地：中国大陆
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T11331FTI 276 TFA；化合物 T11331FTI 276 TFA
FTI 276 TFA is effective against plasmodium falciparum and humans.It is a protein-based nikyltransferase (PFT) inhibitor with an IC50s of 0.9 nM and 0.5 nM, respectively.
价 格：￥电议型 号：T11331产 地：中国大陆
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T11327LFR 167653 free base；化合物 T11327LFR 167653 free base
FR 167653 free base is an orally active p38 MAPK inhibitor and is effective in treating inflammation, relieving trauma, and ischemia-reperfusion injury in vivo. It also is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity.
价 格：￥电议型 号：T11327L产 地：中国大陆
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T11276Fexofenadine-d6；非索非那定 d6MDL-16455-d6|||Terfenadine carboxylate-d6；MDL-16455-d6|||Terfenadine carboxy
Fexofenadine-d6 (MDL-16455-d6) is the deuterium substituent of Fexofenadine and can be used as an internal standard for the determination of non-sofenadine concentrations in human plasma.
价 格：￥电议型 号：T11276产 地：中国大陆
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T11212EPAC 5376753；化合物EPAC 53767535-{[5-(2,4-dichlorophenyl)furan-2-yl]methylidene}-2-thioxodihydropyrimid
EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 ?M in Swiss 3T3 cells.
价 格：￥电议型 号：T11212产 地：中国大陆
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T11176Eliglustat hemitartrate；依利格鲁司特酒石酸盐Genz-112638|||Eliglustat tartrate；Genz-112638|||依利格鲁司特酒石酸盐|||Eligl
Eliglustat hemitartrate (Genz-112638) , with an IC50 of 24 nM, is a specific, potent, oral active glucocerebral glycosidase inhibitor.
价 格：￥电议型 号：T11176产 地：中国大陆
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T11101DS08210767；化合物DS08210767DS08210767
DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.
价 格：￥电议型 号：T11101产 地：中国大陆
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T11076Dooku1；化合物Dooku1Dooku1
Dooku1 is an analog of Yoda1 and a selective antagonist of endogenous Piezo1 channels. Dooku1 inhibits Ca2+ entry induced by 2μMYoda1 with IC50 values of 1.3μM (in HEK 293 cells) and 1.5μM (in HUVEC). Dooku1 inhibits Yoda1-induced aortic relaxation.
价 格：￥电议型 号：T11076产 地：中国大陆
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T11011Dexpramipexole dihydrochloride；右旋普拉克索二盐酸盐KNS-760704 dihydrochloride|||R-(+)-Pramipexole dihydrochlor
Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine agonist.
价 格：￥电议型 号：T11011产 地：中国大陆
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T10992Delamanid D4；化合物 T10992OPC-67683 D4；OPC-67683 D4
Delamanid D4 is deuterium-labeled Delamanid. Delamanid is a newer mycobacterial cell wall synthesis inhibitor that inhibits the synthesis of mucus acid.
价 格：￥电议型 号：T10992产 地：中国大陆
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T10988LDegarelix acetate(214766-78-6 free base)；化合物Degarelix acetateDegarelix acetate(214766-78-6 free base
Degarelix acetate is a competitive and reversible antagonist of gonadotropin-releasing hormone receptor (GnRHR) .
价 格：￥电议型 号：T10988L产 地：中国大陆
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T10976DC4SMe；化合物 T10976DC4SMe
The IC50s of DC4SMe on Ramos, Namalwa and HL60 / s cancer cells were 1.9 nM, 2.9 nM and 1.8 nM, respectively. DC4SMe can be used for targeted therapy of tumors. DC4SMe is a phosphate prodrug of the cytotoxic DNA alkylating agent DC4 and can be used in the synthesis of antibody-drug conjugates (ADC).
价 格：￥电议型 号：T10976产 地：中国大陆
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T10964LDB1976 dihydrochloride；DB1976盐酸盐DB1976 hydrochloride|||DB1976 2HCl；DB1976 hydrochloride|||DB1976 2HC
DB1976 dihydrochloride (DB1976 2HCl) , a transcription factor PU.1 inhibitor with potential anti-inflammatory activity, slowed down inflammation and fibrosis and improved glucose homeostasis and dyslipidemia in mice in in vivo experiments.DB1976 dihydrochloride promotes apoptosis and may be used in studies of metabolic dysfunction and non-alcoholic steatohepatitis.
价 格：￥电议型 号：T10964L产 地：中国大陆
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T10964DB1976；化合物DB1976DB1976
DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, KD of 12 nM) in vitro. DB1976 has Apoptosis-inducing effect.
价 格：￥电议型 号：T10964产 地：中国大陆
